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Spannr / Glossary / Gene

Gene

A genes is a basic unit of heredity, the blueprints that define the characteristics of living organisms. These microscopic entities play a pivotal role in shaping our traits, determining everything from our eye color to our susceptibility to certain diseases. 

What is a Gene?

At its core, a gene is a segment of DNA (deoxyribonucleic acid), the molecule that serves as the repository of genetic information in all living cells. DNA consists of two long strands arranged in a double helix, with each strand made up of nucleotides. These nucleotides contain the genetic code, represented by the letters A (adenine), T (thymine), C (cytosine), and G (guanine).

Structure of Genes

Genes are specific sequences of nucleotides within the DNA molecule. Each gene carries instructions for synthesizing a particular protein or, in some cases, RNA molecules that play essential roles in cellular functions. The arrangement of nucleotides in a gene determines the order in which amino acids are assembled during protein synthesis, ultimately influencing the structure and function of the protein produced.

Function of Genes

The primary function of genes is to provide the instructions necessary for the synthesis of proteins, which are the building blocks of cells and perform various functions in the body. Proteins play crucial roles in processes such as metabolism, immune response, and cell structure. Additionally, genes regulate the timing and rate of cellular activities, contributing to the overall development and functioning of an organism.

Inheritance and Genetics

Genes are passed from one generation to the next through the process of reproduction. Offspring inherit a combination of genes from both parents, resulting in unique combinations of genetic material. The field of genetics explores the inheritance patterns of genes and how variations in genes contribute to the diversity observed among individuals within a population.

Genetic Code and Protein Synthesis

The genetic code is the set of rules by which information encoded in DNA is translated into proteins. Each sequence of three nucleotides, known as a codon, codes for a specific amino acid or serves as a signal to start or stop protein synthesis. The intricate dance between DNA, RNA (ribonucleic acid), and cellular machinery orchestrates the precise assembly of proteins, ensuring the proper functioning of the organism.

Genetic Mutations and Variations

While genes carry the instructions for the development and functioning of an organism, genetic mutations can introduce variations in the genetic code. Mutations can occur spontaneously or be induced by external factors such as radiation or certain chemicals. Some mutations may have no noticeable effect, while others can lead to changes in an organism's traits or contribute to the development of genetic disorders.

Kaplan-Meier estimator

Kaplan-Meier estimator is a system used to measure the survival time after treatment.

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