Longevity Industry Jobs

We are seeking a Finance Manager to join our financial reporting team, supporting the implementation of the Company’s Sarbanes Oxley 404 framework as well as driving process efficiency and continuous improvement across the Finance function. You would play a key role in the group’s consolidation process and external reporting requirements.

Please note: this is a hybrid role and occasional travel to our Oxford office is required, ideally for 1-2 days per fortnight or more, and we are flexible to discuss other arrangements.

As the Finance Reporting Manager, you will have the opportunity to:

• Play a critical role in the development and implementation of our internal controls and compliance programs.
• Support regular control performance assessments, ensuring control objectives are met and evidenced appropriately.
• Support the design of remediation plans where controls are not operating as designed, working with process owners to facilitate improvements on a continual basis.
• Assist the preparation of consolidated external reporting requirements and individual subsidiary statutory accounts.
• Act as a key contact for our external auditors to facilitate audit activities.

Requirements

• 1-2 years post qualified experience, for example ACA/ACCA qualification or equivalent.
• Familiarity with IFRS accounting principles.
• External or internal audit experience.
• Hands-on experience with SOx requirements is preferred; knowledge of SOx requirements is essential.
• Organised individual with strong attention to detail and ability to prioritise and manage time effectively.
• Excellent interpersonal, oral, and written communication skills (fluency in English is essential).

Exscientia is a global leader in applying Artificial Intelligence (AI) to modernize the way new medicines are created. We do this by applying the latest research, machine learning and modern high-performance computational methods to transform drug design.

Exscientia developed the first-ever functional precision oncology platform to successfully guide treatment selection and improve patient outcomes in a prospective interventional clinical study, as well as to progress AI-designed small molecules into the clinical setting.

We're seeking a Service Desk Analyst to join us on an initial 6 month contract. As the Service Desk Analyst you will contribute to our mission to develop better medicines, faster, to people around the world

As the Service Desk Analyst you will have the opportunity to

• Serve as the first point of contact for customers seeking technical assistance and guidance
• Act as a focal point for customers and colleagues alike for communications around issues and requests
• Perform basic troubleshooting using knowledge articles and help the continuous improvement of the knowledge repository
• Determine the best solution based on the issue and details provided by customers
• Pass on any feedback or suggestions by customers to the appropriate team
• Identify and suggest possible improvements on procedures

What's Required?

• Customer-oriented and passionate about good service
• Experience working within a Technical Service Desk role
• Experience troubleshooting basic technical issues
• Diligent in your approach to recording details accurately
• Excellent communication skills

Exscientia embraces equal opportunity and is committed to providing a diverse and inclusive community where everybody feels welcome. We welcome applications from all people regardless of background. If you're a Service Desk Analyst looking for a new challenge at the forefront of AI then please apply today to learn more!

The Clinical Scientist will be responsible for supporting and coordinating specific clinical development activities related to assigned program and for providing clinical development expertise and input at various cross-functional teams.

As the Clinical Scientist you will have the opportunity to:

• Assist in the timely medically and scientifically sound development of key study documents including but not limited to protocols, investigator's brochures, study plans, informed consents, etc.
• Assist in the review of regulatory documents
• Assist in monitoring data and reporting safety-related events.
• Interact with investigators at sites during the start-up, conduct and, close-up of the study to enable quality, compliance and patient safety at the trial, site and patient level.
• Contribute to contract research organization / vendor selection to ensure study is conducted consistent with protocol requirements, clinical plan expectations, and study timelines; this includes input into site selection, study manuals, and ensuring medical/technical requirements for data integrity are applied
• Ensure GCP and Standard Operating Procedures are followed.
• Assist in data review and interpretation including interim and final study reports before they are approved.
• Support the clinical lead, clinical biomarker lead and clinical pharmacology lead
• Interact with several other internal functions including operations, and regulatory affairs among others.
• Liaise with Key Opinion Leaders and Principal Investigators in countries to build a Key Opinion Leaders /Principal Investigators network for EXS trials
• In addition to study level activities, the clinician scientist may participate in standing committees, review compounds for potential out-licensing and provide assistance to business development on market opportunities as needed.

Requirements

• BSc, MSc or PhD in Medicine/Nursing/Pharmacy with relevant experience (MSc +7-10 years / PhD +5-7 years) in pharmaceutical industry
• Must have experience working on multi-functional global development teams.
• Preferable to have experience in drug development within the biopharmaceutical industry and/or prior experience in running trials in Oncology (+5 years at least)
• Must be able to evaluate, interpret and synthesise scientific data, and can verbally present and critically discuss clinical trial data in internal and external meetings.
• Must have excellent verbal & written communication skills in English.
• Demonstrable multitasking, project management, and execution skills.
• Good time management, and strong attention to detail.
• Good interpersonal skills, including communication, presentation, persuasion, and influence.

Benefits

• Work together to make a positive contribution to patients by revolutionising the pharmaceutical industry through AI-driven discovery.
• We will work with you to kick-start or further grow your career - from funding for professional development and conference attendance. To the opportunity to acquire valuable skills, work on problems that matter, and learn from world-class technological and scientific leaders.
• Opportunity to join an inclusive, collaborative and intellectually stimulating culture
• We will work with you to provide a highly competitive compensation as we continue to grow and thrive.
• Our team's health and well-being is important to us we offer a generous holiday allowance, provide flexible working and remote working to encourage all of our team to manage their own work, time and life along with wellbeing and mindfulness support.
• When you are in the office, you will have access to a kitchen stocked with an endless supply of food for all employees. Along with access plenty of break out areas so you can get to know the people you are working with. Some of the best ideas start with a coffee break!
• Hear from our team why they enjoy working here

The Associate Director Software Project Manager drives our medical software product development of our exciting oncology platform. It is your responsibility to develop best-in-class software applications in the medical device area. Your project team includes a cross-functional Scrum team of software engineers, verification engineers and quality engineers.

As the Associate Director Software Project Manager will have the opportunity to:

• Be responsible for the implementation of a medical device software project and the lead of an agile software team in design, implementation and testing of the software
• Ensure the project quality, timelines and budget
• Implement and resolve technical customer requirements
• Measure project performance using appropriate tools and techniques
• Apply classic and agile project methodologies like Scrum
• Control the design, implementation and documentation of new software functionalities in a technical environment
• Be in charge of team and talent management. Develop and expand the skillset of your team

Requirements

• Bachelor's or Master's degree in Computer Science or other related experience
• 5+ years of experience working in the software development with strong technology background
• 3+ years of project management experience
• Experience in Medical SW Development (ISO 13485, IEC 62366, IEC62304)
• Experiences in personal management
• Strong expertise of modern infrastructure and workplace technologies
• Strong technical project management skills
• Strong team leadership skills.
• Good understanding of agile methodologies

Benefits

We will work with you to provide a highly competitive compensation in accordance with the Austrian collective bargaining agreement, starting from a minimum of 70.000,- € gross per year. We will negotiate an attractive package and overpayment based on your background and previous work experience

For Exscientia's exciting oncology platform the Lead Test Automation Engineer based in our Vienna office you will be responsible for the software testing and verification of the platform. Developing lean test strategies and implementing high coverage of test automation are key to support
the efficiency of our development.

As the Lead Test Automation Engineer you will have the opportunity to:

• Lead and support the verification of medical device software projects and act as a key link between testing and development
• Support the verification in maintaining and executing manual and automated tests (test models and test cases)
• Further develop the test infrastructure (tooling, CI/CD, reporting)
• Support the execution of test concept and implementation of continuous integration
• Develop procedures in the area of test automation
• Write clear and detailed technical specifications and documentation

Requirements

• Bachelor's or Master's degree in Computer Science, Engineering or a related technical field of study
• Several years of experience in the field of medical device software verification in an agile environment
• Several years of experience in test automation
• Experience with at least one of the following or equivalent tools: Selenium, WinAppDriver, MS UI Automation Framework, Appium, Coded UI, Tricentis Tosca
• Motivated with a can-do attitude

Benefits

Exscientia provides a competitive compensation package in accordance with the Austrian collective bargaining agreement, starting from a minimum of 70.000,-€ gross per year. We will negotiate an attractive package and overpayment based on your background and previous work experience.

As the Senior Software Engineer you will help us implement interfaces for both IoT instrumentation and the web apps that support their operation. Whilst being part of helping us automate the drug discovery process!

Responsibilities

• Implement custom components and views for controlling IoT analytical tools using Vue/Nest.
• Implement instrumentation control using ROS2 python and C++
• Implement database functionality using MongoDB
• Contribute to automation test suite using Vitest, Jest and Cypress
• Work with our team to ensure your solutions meet performance specifications for the device they will be running on.

Requirements

• Experience building custom components with full-stack development.
• Experience developing software for hardware devices, with use of actuators and sensors.
• You are experienced in Python.
• You routinely write and automate tests for projects you support.
• You have experience with Node (or any newer flavors like Nest.js or Next.js).
• You have experience building and testing data heavy web applications.
• You are comfortable picking up designs from Figma or a similar design tool.
• You are comfortable developing, refining, and sharing components in a tool like Storybook.js.
• You find it easy to collaborate with designers to find feasible solutions to challenging usability problems.
• You are all about the design details when it comes to implementation and providing the best user experience.
• You have experience with MongoDB.

As a DMPK project leader, you will represent DMPK on cross-disciplinary discovery and development project teams and will have responsibility for the overall non-clinical DMPK with project accountability from early drug discovery towards candidate drug selection and in the clinical phases of development. The candidate will support several projects across different therapeutic areas and will lead the DMPK interactions with the full range of disciplines and functions involved: medicinal chemistry, pharmacology, toxicology, pharmaceutical sciences, clinical pharmacology etc.

As the DMPK Project Leader you will have the opportunity to:

• Design, commission and conduct appropriate experimental studies to support compound design, project progression and candidate selection to understand, risk mitigate and resolve project ADME challenges
• Apply an expert understanding of DMPK, including pre-clinical PK, translational PK and PK-PD, physicochemical property assays and biotransformation reactions and will be expected to provide scientific expertise and strategic direction to assigned projects
• Provide strong support to AI/ML teams to identify, generate, interpret and challenge data from which to build and improve predictive DMPK models to allow virtual screening of new compound designs
• Progress molecules with appropriate ADME and pharmacokinetic properties, through lead optimisation to clinical candidate nomination and expected to demonstrate awareness of project status at all time
• Support and challenge if appropriate the interpretation of results and translation into objectives for design
• Prepare the DMPK part of internal/regulatory documents (e.g., IND, IB, NDA)

Requirements

• BSc, MSc or PhD in Chemistry/Biochemistry/Pharmacology/Pharmacokinetics with relevant experience (MSc + 7-10 years / PhD + 5-7 years) in the pharmaceutical industry or academia
• Industry experience in ADME and pharmacokinetics and a proven track record of scientific achievement and project influence
• Broad understanding of relevant DMPK areas such as physicochemical properties, drug metabolising enzymes and transporters, biotransformation reactions, pharmacokinetics, IVIVc, allometric scaling and human dose predictions
• Ability to translate data into project relevance to anticipate and/or mitigate project issues
• Strong customer focus with the ability to have robust discussions with project leaders and key stakeholders to ensure that project, scientific and resource demands are aligned
• Bring a fresh perspective into the group and the enthusiasm to tackle new challenges and learn new skills
• Flexibility and able to work across multiple projects

Benefits

• Work together to make a positive contribution to patients by revolutionising the pharmaceutical industry through AI-driven discovery.
• We will work with you to kick-start or further grow your career - from funding for professional development and conference attendance. To the opportunity to acquire valuable skills, work on problems that matter, and learn from world-class technological and scientific leaders.
• Opportunity to join an inclusive, collaborative and intellectually stimulating culture
• We will work with you to provide a highly competitive compensation as we continue to grow and thrive.
• Our team's health and well-being is important to us we offer a generous holiday allowance, provide flexible working and remote working to encourage all of our team to manage their own work, time and life along with wellbeing and mindfulness support.
• When you are in the office, you will have access to a kitchen stocked with an endless supply of food for all employees. Along with access plenty of break out areas so you can get to know the people you are working with. Some of the best ideas start with a coffee break!
• Hear from our team why they enjoy working here

All of our innovation is driven by people; highly talented multi-disciplinary teams that work collaboratively to solve real-world drug discovery problems. Following multiple partnerships with many leading pharmaceutical companies and research institutes, we have a robust and rapidly expanding portfolio of projects, and we are looking to substantially expand our DMPK group.

The DMPK department within Exscientia is strengthening its team and is currently looking for a talented individual who has a passion for DMPK science and translational PK/PD modelling. In this role you will work in a collaborative, multidisciplinary environment, using and building on your current PK/PD knowledge to improve project team decision making based on deeper understanding of concentration-effect relationships. You will contribute to activities including target selection, molecule identification, experimental design, integrated efficacy and safety evaluation, dose prediction, biomarker selection and
clinical trial design.

As the PK/PD Modeller you will be responsible for:

• Building and applying PK/PD models to influence critical decisions in drug discovery and development, including target selection, lead optimisation, candidate selection and early clinical development.
• Developing and executing a modeling-based strategy for preclinical projects, and leading project team discussions on prediction of human dose prior to candidate selection.
• Working with other preclinical scientists within matrix teams to agree the design and interpretation of preclinical studies and define project direction
• Using translational PK/PD modeling as a tool to generate hypotheses and design better, model-informed experiments.
• Establishing concentration-effect relationships from preclinical experiments and providing translational modeling to predict human pharmacological and toxicological effects and human doses, as well as influence early clinical trial design.
• Providing strategic input through modeling and simulation to enable rapid and efficient project progression across a portfolio of projects spanning early discovery through early clinical development
• Establishing strong relationships within Discovery and Early Development with the relevant functions, e.g. DMPK, Toxicology, Translational Medicine, Clinical Pharmacology, etc.

Requirements

• BSc, MSc or PhD in Chemistry/Biochemistry/Pharmacology/Pharmacokinetics with relevant experience (MSc + 7-10 years / PhD + 5-7 years) in the pharmaceutical industry or academia
• Industry experience in ADME and PK/PD modelling and a proven track record of scientific achievement and project influence
• Deep mathematical modeling experience (e.g. PK/PD and PBPK) including integration of multidisciplinary data and application of the models to answer practical questions that have a positive impact on program direction
• Good working knowledge of software packages to enable PK/PD and PBPK modelling (e.g. WinNonLin/Phoenix, Monolix, GastroPlus, etc.)
• Concrete examples of project team support through identifying, developing, and applying preclinical PK/PD modeling techniques
• Ability to interpret, integrate, and translate data from multiple sources into model-based projections and effectively communicate results to project teams
• Strong customer focus with the ability to have robust discussions with project representatives and key stakeholders to ensure that project, scientific and resource demands are aligned
• Bring a fresh perspective into the group and the enthusiasm to tackle new challenges and learn new skills
• Flexibility and capacity to work across multiple projects

The Discovery Toxicologist will be part of the Preclinical Development group and will provide scientific expertise and leadership for the safety assessment of Exscientia programs from early discovery, with additional opportunities to input in to the development of predictive toxicology methodologies. You will contribute to the selection of novel drug targets and optimisation of novel candidate molecules using innovative molecular, cellular and in vivo technologies to maximise predictive safety science and investigative toxicology.

As the Drug Discovery Toxicologist will have the opportunity to:

• Provide expert input, guidance and strategy on project safety assessments, with a specific focus on early discovery projects.
• Act as a key resource for early safety assessment during the drug discovery phase, providing scientific knowledge and expertise to cross-functional project teams.
• Develop and implement toxicology screening strategies to predict, assess and mitigate target- and drug-related safety risks in support of the drug discovery portfolio.
• Refine and implement innovative experimental strategies and use the data to assess and /or provide mechanistic understanding of safety issues
• Collaborate with CROs to ensure best practice for in silico and in vitro safety assessment
• Potential to develop drug discovery safety strategy for biologics
• Prepare verbal and written summaries for internal discussions. Work with the Discovery teams to develop optimal strategies to address specific safety issues within project teams
• Present summary data to project teams, Exscientia senior leadership and external partners as needed

Requirements

• DVM, Pharm D, Ph.D in toxicology, Pathology, Physiology, Biochemistry or expertise in related biological scientific disciplines, with an emphasis on Oncology/Immunology is preferred. Board Certification in Toxicology (DABT/ERT) is a plus
• 10+ years experience in discovery toxicology in the Biotech/Pharma industry
• Experience with in silico and in vitro safety assessment is a must; experience in NAMs such as organ-on-a-chip/organoids will be a plus
• An in-depth knowledge of discovery toxicology, and experience designing and critically evaluating results of exploratory toxicology studies
• An understanding of in vitro to in vivo translation of potential toxicities and implications for human safety
• Broad background in novel methods of identifying potential toxicities and developing risk mitigation plans
• Experience with the use of AI-tools to predict toxicology endpoints would be advantageous
• Experience in project team membership as toxicology representative in a matrix environment would be preferred
• Highly motivated scientist, who can work independently, with excellent oral/written communication skills

Reporting into the Synthetic and Medicinal Chemistry group, this position will strategically support ongoing synthetic chemistry with our CRO partners. The successful applicants will be able to demonstrate an excellent level of synthetic chemistry knowledge gained within an industrial environment and be up to date with modern synthetic techniques. The position in the first instance is a non-lab based role, however there may be scope to integrate into the synthetic chemistry team in our new Milton Park labs at a later date. You will also be in the position to shape and influence the medicinal chemistry and design strategies by informing design approaches in a synthesis led manner. Managing building blocks and scale-up strategies towards the delivery of large-scale batches (100s gram) will complete the core elements of the role.

You will be responsible for conceiving innovative synthetic strategies, using your expertise to help solve complex chemistry problems and troubleshoot ongoing chemistry with our CRO partners to deliver the next generation of medicines. Closely collaborating with internal research and development teams to understand their needs and provide technical expertise on sourcing options.

As the (Senior) Researcher you will have the opportunity to:

• Drive the delivery of new target molecules with our outsourcing partners. As a highly trained and experienced synthetic chemist you will take responsibility for trouble shooting synthetic chemistry
• Manage resource allocation and take shared responsibility with project teams to deliver high quality molecules that meet candidate milestones
• Broaden your knowledge in the areas of AI driven medicinal chemistry, automated synthesis and synthesis informatics
• On occasion, collaborate with the technology development team to support the delivery of key platform improvements
• Coordinate the transfer of medicinal chemistry routes to large scale synthesis of API (CMC) enabling preclinical and clinical development

Requirements

• Educated to BSc level with a minimum of 5+ years of experience or to PhD level with 3+ years experience of industrial synthetic / medicinal chemistry
• Hands-on experience of modern synthetic methods and the application towards the synthesis of small molecule drugs
• Excellent retrosynthetic knowledge
• Strong track record in trouble shooting and problem solving synthetic chemistry
• Foundational understanding of process safety and scale-up considerations
• Strategic thinking
• Highly motivated with a positive collaborative mind set
• Strong interpersonal skills, as well as the ability to function in a multidisciplinary team environment
• Strong written and verbal communication skills
• A broad understanding of the drug discovery process from hit finding to candidate selection
• Experience of managing outsourced chemistry (whilst desirable this is not a necessity)

We are seeking an experienced Head of People for our Vienna office, working as part of our international People team.

This role will suit someone with a background in Austrian human resources management who is used to working in an international environment. You will lead and implement strategic People efforts in Austria, functioning as the point of contact for high-level requests and providing in-depth perspective on initiatives, based on Austrian employment situations and trends. You will use your professional expertise in building and supporting interdisciplinary teams, and implementing sleek People processes and initiatives, to contribute to our mission: making better drugs, faster.

Please note, this is a temporary position to provide maternity cover support, ideally starting in mid-May. This role is hybrid so regular travel to our Vienna office is required (approx. two days per week in Floridsdorf, 1210), with flexibility to work from home the remaining time.

As Head of People, Austria you will have the opportunity to:

• Act as the point of contact for the People strategy in Austria, maintaining an overview of site organisation, hiring plans, structure and collaboration opportunities with adjacent teams (e.g. Facilities, Hospitality, EHS, Finance).
• Work on global People projects and initiatives, partner with the global team, give input on strategy and roll out plans to ensure compatibility with Vienna site needs and Austrian employment law.
• Collaborate with the People Essentials team to ensure compliance and effective communication with stakeholders; manage complex employee relations cases, also in close collaboration with division-specific People Business Partners.
• Maintain up-to-date knowledge of trends, regulatory developments and HR-related studies in Austria, the DACH region and wider Europe to inform Exscientia's people efforts.
• Support EOR (employer of record) employees in European countries.

Requirements

• Proven experience for minimum 4 years in an HR role, ideally as a generalist with involvement in strategic organisation building and/or business partnering for a site.
• Bachelors or higher degree, ideally in Human Resources Management, Business Management, Psychology or similar fields is preferred, but not essential.
• Excellent written and spoken English and German skills. Fluency in German is an essential requirement due to the nature of this role, but please note English is our working language across the company.
• Experience working in international organisations.
• Strong interpersonal communication and presentation skills, with time management skills and resilience to pressure.
• Ability to work independently representing Exscientia values and policies for the Vienna location.

Benefits

Exscientia provides a competitive compensation package in accordance with the Austrian collective bargaining agreement, starting from a minimum of 70.000,-€ gross per year. We will negotiate an attractive package and overpayment based on your background and previous work experience.

We are looking for a highly motivated technical research associate to join Biobank Operations within our Translational Research and Precision Medicine teams. All of our Innovation is driven by people - highly talented multi-disciplinary teams that work collaboratively to solve real world drug discovery problems. In this role you will be responsible for supporting existing programs as well as clinical studies and trials - and work in a team of experts to improving scalability of existing workflows. You will work closely with a team of distinguished scientists at the cutting edge patient centric drug design. The technical research associate position within this operations and research and development team is crucial to our continuous growth.

As the Technical Research Associate you will have the opportunity to:

• Contribute to the design and further optimization of workflows within Translational Research and Precision Medicine Vienna team using flow cytometry and other phenotypic assays.
• Apply cutting-edge high content microscopy and image analysis technology developed by our RnD teams to questions of high clinical relevance.
• Support and work within an incredibly motivated and talented, international and multidisciplinary team to make better drugs for the right patients faster.
• Establish and maintain documents and protocols to ensure reproducibility and experiment documentation according to Exscientia’s Quality Management System and Good Documentation Practice.

Requirements

• BSc or MSc in biomedical sciences (molecular biology, biochemistry or similar)
• Experience with common molecular biology techniques including:
• Cell culture
• Flow cytometry
• DNA / RNA prep
• Experience with handling and working with primary human tissues is an advantage.
• Experience in working under good laboratory practice (GLP) and good documentation practice (GDP) guidelines is a bonus.
• Excellent written and oral communication skills
• Diligence and reliability in collaborations with attention to detail

Benefits

We will work with you to provide a highly competitive compensation in accordance with the Austrian collective bargaining agreement, starting from a minimum of 43.000,- € gross per year. We will negotiate an attractive package and overpayment based on your background and previous work experience

We’re seeking a Structural Immunoinformatics scientist, focused on the computational modeling, design, and developability of biomolecules, to support Exscientia’s Biologics pipeline which uses virtual screening, in silico affinity maturation, multi-parameter optimization, active learning, and experimental validation through robotics & automation. We are designing a truly novel, data and process centric platform and this is a fantastic opportunity to apply your hard-earned skills in a team first mission driven company.

As a Structural Immunoinformatics Scientist you will have the opportunity to perform:

• Biologics Engineering: Implement structure-based protein engineering pipelines for virtual screening, epitope mapping & targeting, affinity maturation, evolutionary consensus design, mutagenesis, CDR loop modeling, stability of antibody framework regions, and enhancing in vivo half-life
• Computational Biophysics: Predict physicochemical and thermodynamic properties of biologics, to calculate metrics such as folding stability, binding energetics, hydrophobicity, electrostatics, aggregation, self-association, viscosity, glycan shielding, and post-translational modifications
• Generative AI Design: Integrate the biologics engineering and computational biophysics workflow into Exscientia’s generative design pipeline, to provide structural feature space for geometric deep learning and diffusion models
• Automation & Experimental Design: Build an integrated, automated computational and experimental data generation platform for multi-parameter optimization & active learning, providing in silico pipelines to predict and model _in vitro _data such as expression (UV-Vis), binding kinetics (surface plasmon resonance), folding stability (differential scanning fluorimetry), aggregation (static & dynamic light scattering), neutralization (IC50), and structure (cryo-electron microscopy)

Requirements

• Ph.D. degree in Computational Biology, Biophysics, Structural Biology, Physics, Computer Science, Computational Chemistry, Artificial Intelligence or related disciplines, or master’s degree focusing on computational modeling, design, and characterization of proteins, antibodies, or biomacromolecules
• Strong background in computational protein engineering and design, or computational biophysics for calculating structural and physicochemical features
• Proven experience with relevant protein modeling and design software: For example, Rosetta, RosettaFold, AlphaFold2, MOE, tools for evolutionary consensus design, enhancing thermostability, and germline targeting (e.g., HHBLITS, MMSEQS2, KA-Search, PROSS, FireProt, ProteinMPNN)
• Experience in ensemble or molecular dynamics analysis of biomolecules for biophysical characterization, using tools such as AMBER, CHARMM, GROMACS, YASARA, and physicochemical property prediction (e.g., Therapeutic Antibody Profiler, CamSol, Spatial Aggregation Propensity, Spatial Charge Map)
• Proficient in programming and software deployment: For example, Python, C++, HPCs, Linux, AWS, Slurm
• Preferable background in developing machine learning models for structure-based prediction, docking, design, or characterization of biologics (e.g., RFdiffusion, dMASIF, DeepSCM, ABlooper, IgFold, ImmuneBuilder)

As the Senior Front-end Engineer you will help us implement interfaces for both IoT instrumentation and the web apps that support their operation. Whilst being part of helping us automate the drug discovery process! This role can be based in our Oxford office or remotely within the UK.

Responsibilities

• Implement custom components and views for controlling IoT analytical tools using Vue/Nest.
• Contribute to automation test suite using Vitest, Jest and Cypress
• Client state management using Pinia store
• Interface with server REST API
• Work with our team to ensure your solutions meet performance specifications for the device they will be running on.

Requirements

• You are comfortable picking up designs from Figma or a similar design tool.
• You are comfortable developing, refining, and sharing components in a tool like Storybook.js.
• You have experience building and testing data heavy web applications.
• You routinely write and automate tests for projects you support.
• You are all about the design details when it comes to implementation and providing the best user experience.
• Experience building custom components with full-stack development.
• You find it easy to collaborate with designers to find feasible solutions to challenging usability problems.
• You have experience with Node (or any newer flavors like Nest.js or Next.js).
• Experience developing software for hardware devices, with use of actuators and sensors.
• You are experienced in Python.
• You have experience with Node (or any newer flavors like Nest.js or Next.js).

• Act as the key link between Exscientia scientists and global CROs to ensure delivery of outsourced work in accordance with requirements and contractual obligations.
• Lead continuous improvement activities, applying problem solving skills to identify workflow efficiencies and implement technology solutions to enhance processes. Working with internal stakeholders to ensure learning is captured and incorporated into processes and practices.
• Support CRO governance to ensure these dovetail effectively with Exscientia drug project portfolio management.
• Measure delivery metrics by CRO partners and and communicate key internal stakeholders
• Act as point of contact/outsourcing expert for Exscientia

• Experience of drug discovery gained from working in either a pharmaceutical company, biotech or in a CRO
• Undergraduate science degree
• Excellent organisational and stakeholder management skills
• Experienced at issue resolution, problem solving and simplification of processes
• Strong communication skills

• Work together to make a positive contribution to patients by revolutionising the pharmaceutical industry through AI-driven discovery.
• We will work with you to kick-start or further grow your career – from funding for professional development and conference attendance, to the opportunity to acquire valuable skills, work on problems that matter, and learn from world-class technological and scientific leaders.
• Opportunity to join an inclusive, collaborative and intellectually stimulating culture
• We will work with you to provide a highly competitive compensation as we continue to grow and thrive.
• Our team’s health and well-being is important to us - we offer a generous holiday allowance, provide flexible working and remote working to encourage all of our team to manage their own work, time and life along with wellbeing and mindfulness support.
• Hear from our team about why they enjoy working here

• Routine cell maintenance and scaling of Insect and Mammalian cell lines.
• Production of recombinant baculovirus.
• Transfection/infection for recombinant protein expression.
• Expression of recombinant proteins in E. coli
• Attention to detail including good record keeping.
• To author high quality reports and data summaries.
• To communicate updates to projects.
• To work to the highest scientific standards

• Experience in cell culturing techniques in both Mammalian and Insect cell lines. Cell stock maintenance and scale up for protein expression.
• A demonstrable analytical approach to problem solving.
• The ability to work as part of a team.
• Flexible, adaptable and able to work across multiple projects.

• Experience in growing cells in fermenters/reaction vessels
• Experience of transfection/infection in Insect cells (transient and Baculovirus) and Mammalian cells (transient, BacMam and LentiX).
• Experience in expressing proteins in E. coli
• Previous work experience in an industrial or high-throughput environment.
• Demonstrated ability to optimise workflows.
• Experience in working with and adopting complex laboratory automation/liquid handling.
• Experience with LIMS systems.

• Work together to make a positive contribution to patients by revolutionising the pharmaceutical industry through AI-driven discovery.
• We will work with you to kick-start or further grow your career – from funding for professional development and conference attendance. To the opportunity to acquire valuable skills, work on problems that matter, and learn from world-class technological and scientific leaders.
• Opportunity to join an inclusive, collaborative and intellectually stimulating culture
• We will work with you to provide a highly competitive compensation as we continue to grow and thrive.
• Our team’s health and well-being is important to us we offer a generous holiday allowance, provide flexible working and remote working to encourage all of our team to manage their own work, time and life along with wellbeing and mindfulness support.
• When you are in the office, you will have access to a kitchen stocked with an endless supply of food for all employees. Along with access plenty of break out areas so you can get to know the people you are working with. Some of the best ideas start with a coffee break!

• You will have experience working in a sample management laboratory environment
• You will have experience using weighing balances and basic chemical handling procedures
• You will have experience working with liquid handling automation
• You will be excited by the challenge of working with multiple scientific teams in the lab
• You will be looking to build your skillset and learn from new experiences in a growing laboratory

• Supporting sample logistics activities such as weighing, solubilisation, receiving, storage and shipping chemical compounds using LIMS system
• Working with liquid handling automation producing assay ready plates
• Supporting our future fully automated sample management platform
• Maintaining laboratory supplies for Sample Logistics
• Ordering and receiving laboratory consumables
• Maintaining a clean laboratory working environment
• Working closely with and supporting core laboratory teams
• Maintaining relationships with external suppliers

• Preferably biological/life science lab experience
• Academic or industrial background
• An understanding of health and safety
• Strong organisational skills
• Attention to detail
• Excellent interpersonal, oral and record-keeping skills: you will need to communicate effectively with team members and with external suppliers

• Work together to make a positive contribution to patients by revolutionising the pharmaceutical industry through AI-driven discovery.
• We will work with you to kick-start or further grow your career - from funding for professional development and conference attendance. To the opportunity to acquire valuable skills, work on problems that matter, and learn from world-class technologyical and scientific leaders.
• Opportunity to join an inclusive, collaborative and intellectually stimulating culture
• We will work with you to provide a highly competitive compensation as we continue to grow and thrive.
• Our team's health and well-being is important to us we offer a generous holiday allowance, provide flexible working and remote working to encourage all of our team to manage their own work, time and life along with wellbeing and mindfulness support.
• When you are in the office, you will have access to a kitchen stocked with an endless supply of food for all employees. Along with access plenty of break out areas so you can get to know the people you are working with. Some of the best ideas start with a coffee break!
• Hear from our team why they enjoy working here

• Define and maintain a compelling end-to-end vision and roadmap for Physics based methods and generative design as part of an automated end to end drug discovery process.
• Align the strategy of your technical areas with the broader strategic vision of the drug design function. Maintain and communicate clear priorities for your teams and the execution strategy towards them.
• Manage strong product development teams that will collaborate cross functionally towards common goals and drive the implementation of their product roadmap with product leads.
• Communicate and evangelise the function strategy and roadmap providing the required details and insights on how specific initiatives will contribute to the vision of the business.
• Collaboratively define the metrics of success in your area that demonstrates the impact of the automated methods on drug design.
• Work collaboratively with UX/Agile delivery and application scientists to maximise business value.
• Build a strong relationship with users and create mechanisms to measure value, sharing best practices and continuous learning.
• Manage the portfolio of ongoing and planned initiatives for your areas, driving the definition of product delivery OKRs while enabling the flow of innovation.
• Ensure high quality communication and transparency across the function and the organisation for activities in design automation.
• Engage broadly across the company to understand demand and future opportunities where technology can improve efficiency and effectiveness.

• You have a good understanding of the drug discovery industry and competitor landscape.
• You can manage multiple cross functional teams that balance the development of complex products and scientific research.
• You apply a metric-driven approach to assess the “success” of the product, both in terms of usability as well as with regard to OKRs.
• You have a good understanding and experience in the application of design principles, user research techniques, engineering principles in software development,
• You have led AI platform infrastructures.
• You have a deep understanding of your product area for physics based methods and generative design.
• A real passion for Product in fast growing organisations.

• 5+ years of product management experience in Pharma, Health Tech or SW engineering organisations.
• Experience in AI product development is a definite plus.
• BSc level or above in a relevant science-based field (e.g., Biology, Biochemistry, Chemistry, Engineering, AI Computer Science, or equivalent domain experience).

• Work together to make a positive contribution to patients by revolutionising the pharmaceutical industry through AI-driven discovery.
• We will work with you to kick-start or further grow your career – from funding for professional development and conference attendance. To the opportunity to acquire valuable skills, work on problems that matter, and learn from world-class technological and scientific leaders.
• Opportunity to join an inclusive, collaborative and intellectually stimulating culture
• We will work with you to provide a highly competitive compensation as we continue to grow and thrive.
• Our team’s health and well-being is important to us we offer a generous holiday allowance, provide flexible working and remote working to encourage all of our team to manage their own work, time and life along with wellbeing and mindfulness support.
• When you are in the office, you will have access to a kitchen stocked with an endless supply of food for all employees. Along with access plenty of break out areas so you can get to know the people you are working with. Some of the best ideas start with a coffee break! 

• Work with mammalian cell transfections with HEK293, CHO cells
• Maintaining mammalian cell suspension cultures
• Establishing high throughput antibody purifications
• Characterise purified antibodies using various biophysical techniques
• Contribute establishing robotics for high throughput antibody expression, purification and characterisation
• Troubleshooting experiments and documenting scientific results

• Ph.D. degree in Biochemistry/ molecular biology/ structural biology or related life sciences discipline or masters degree with relevant industry experience
• Strong background in molecular biology techniques with experience in PCRs, cloning, plasmid preparation and skilled in use of molecular biology softwares for in silico manipulations
• Experience in mammalian cell culture and transfections, recombinant antibody purification and characterisation
• Previous experience in working with automation and experience in antibodies in an high throughput setting
• Flexible person with ability to work within a team and desire to take initiative
• Excellent attention to detail, strong documentation skills, a person with can-do attitude

• Work together to make a positive contribution to patients by revolutionising the pharmaceutical industry through AI-driven discovery.
• We will work with you to kick-start or further grow your career – from funding for professional development and conference attendance. To the opportunity to acquire valuable skills, work on problems that matter, and learn from world-class technological and scientific leaders.
• Opportunity to join an inclusive, collaborative and intellectually stimulating culture
• We will work with you to provide a highly competitive compensation as we continue to grow and thrive.
• Our team’s health and well-being is important to us we offer a generous holiday allowance, provide flexible working and remote working to encourage all of our team to manage their own work, time and life along with wellbeing and mindfulness support.
• When you are in the office, you will have access to a kitchen stocked with an endless supply of food for all employees. Along with access plenty of break out areas so you can get to know the people you are working with. Some of the best ideas start with a coffee break! 

• Ph.D in Biology, Pharmacology, Biochemistry or a related discipline or a BSc/MSc degree with significant relevant experience in the pharmaceutical or biotechnology industry
• Experience of working in small molecule drug discovery pipeline
• Screening of small molecules in plate-based formats
• Experience in data analysis including dose response relationships
• Assay development and assay optimisation
• Sterile techniques and cell culture
• Practical understanding of a wide range of molecular and cell biology techniques such as BRET, HTRF, immunoblotting, InCellWestern, flow cytometry, construct design and DNA sequencing
• Flexible, adaptable and able to work across multiple projects
• Excellent interpersonal and communication skills, both written and verbal - able to communicate technical information to a non-specialist audience

• Prior experience in kinase biology would be a plus but is not essential
• Use of automation, liquid handling and experience with nanolitre dispensing (ECHO/Mosquito)
• Experience of medium to high-throughput screening assays
• Experience with mechanism of action studies or biomarker development
• Working with human primary cells
• Experience with LIMS systems
• Working with external partners and successful transfer of assays

• Work together to make a positive contribution to patients by revolutionising the pharmaceutical industry through AI-driven discovery.
• We will work with you to kick-start or further grow your career – from funding for professional development and conference attendance, to the opportunity to acquire valuable skills, work on problems that matter, and learn from world-class technological and scientific leaders.
• Opportunity to join an inclusive, collaborative and intellectually stimulating culture
• We will work with you to provide a highly competitive compensation as we continue to grow and thrive.
• Our team’s health and well-being is important to us - we offer a generous holiday allowance, provide flexible working and remote working to encourage all of our team to manage their own work, time and life along with wellbeing and mindfulness support.
• When you are in the office, you will have access to a kitchen stocked with an endless supply of food for all employees along with access plenty of break out areas so you can get to know the people you are working with. Some of the best ideas start with a coffee break!

• Bring your vision of state-of-the art lab operations management to our brand new laboratories opening January 2023
• Improve and implement processes that help a growing organisation to thrive
• Lead a highly motivated team and help them to meet their goals
• Work closely together with Clinical Operations to ensure accurate sample processing and management of our biobank.
• Together with Health & Safety team ensure that the lab spaces conform to legal safety standards
• Collaborate with the Quality Management team to ensure standardised and optimised lab operations, while complying with the standard operating procedures (SOPs) in place.

• Extensive experience in managing modern laboratory spaces, ideally in an industry, hospital or pharma setting
• Experience in building, leading and nurturing a team
• Experience of laboratory planning, design or setup, with knowledge of services and facilities required for safe experimental biology and chemical labs
• Ability to work in a fast-paced environment and apply innovative solutions to problems
• A positive can-do attitude
• Excellent communication skills in verbal and written English and German
• Previous experiences in either biological sample handling, microscopy or flow cytometry is a plus
• Knowledge about any type of quality management system would be a benefit

• Work together to make a positive contribution to patients by revolutionising the pharmaceutical industry through AI-driven discovery.
• We will work with you to kick-start or further grow your career – from funding for professional development and conference attendance. To also ensuring you will have the opportunity to acquire valuable skills, work on problems that matter, and learn from world-class technical and scientific leaders.
• Opportunity to join an inclusive, collaborative and intellectually stimulating culture
• A highly competitive compensation package in accordance with the Austrian collective bargaining agreement, starting from a minimum of 45.000,-€ gross per year. We will negotiate an attractive package and overpayment based on your background and previous work experience.
• Our team’s health and well-being is important to us we offer a generous holiday allowance, provide flexible working and remote working to encourage all of our team to manage their own work, time and life along with wellbeing and mindfulness support.
• We offer daily lunch, regular team events and lots of opportunities for casual networking.
• Hear from our team why they enjoy working here

• Mentoring junior team members on their journeys to becoming independent, impactful contributors
• Helping us build the next generation of lab automation, data management and analysis solutions
• Planning, designing and implementing key user facing workflows within the automation platform

• BSc degree in Computer Science, Biochemistry, Chemistry or relevant field
• Mastery of Python
• 5+ years software engineering experience
• Proven ability with front-end frameworks such as React, Vue, or Angular
• Experience with application frameworks such as Django, Flask or Phoenix
• Proven ability with relational data models and database technologies such as Postgres and MariaDB
• Highly motivated, with a track record of taking ownership of complex problems to pragmatically drive and lead projects forwards
• Excellent interpersonal skills with the ability to directly influence requirement

• Experience or interest in Life Sciences / Drug Discovery
• Understanding of scientific libraries such as Pandas, Numpy and SciPy
• Experience with one of the major Cloud vendors AWS, GCP or Azure
• Familiar with physical automation - especially in a laboratory setting

• Work together to make a positive contribution to patients by revolutionising the pharmaceutical industry through AI-driven discovery.
• We will work with you to kick-start or further grow your career – from funding for professional development and conference attendance. To the opportunity to acquire valuable skills, work on problems that matter, and learn from world-class technological and scientific leaders.
• Opportunity to join an inclusive, collaborative and intellectually stimulating culture
• We will work with you to provide a highly competitive compensation as we continue to grow and thrive.
• Our team’s health and well-being is important to us we offer a generous holiday allowance, provide flexible working and remote working to encourage all of our team to manage their own work, time and life along with wellbeing and mindfulness support.
• When you are in the office, you will have access to a kitchen stocked with an endless supply of food for all employees. Along with access plenty of break out areas so you can get to know the people you are working with. Some of the best ideas start with a coffee break!
• Hear from our team why they enjoy working here

• Contribute to cutting-edge research by critically analysing limitations of current methods, ultimately impacting decision making on real drug discovery projects.
• Get first-hand industry experience working in a bio/biotech/pharma.
• Work with industry leaders.
• Develop your programming skills in Python.
• Develop your skills in cheminformatics and molecular representation.
• Gain insight on how software and research is conducted in an industrial setting.

• You are a MSc or PhD student
• You study a science subject related to Computational Chemistry, Cheminformatics, Computational Biology, Biophysics, or related fields.
• You will be able to demonstrate through the selection process, intermediate Python programming experience, using one or more cheminformatic toolkits, such as RDKit, Open Eye, KNIME, etc.
• You can work independently, willing to try to figure things out yourself but not afraid to ask for help when stuck either.
• You are interested in drug discovery.
• You are available between January and May 2023 for a minimum of 12 weeks.
• You are available to work 40 hours per week (including 1 hour for lunch daily).
• You are available to work at least 3 days per week in person at the Miami office (we can be flexible on this).

• Experience with Software Engineering
• CADD Experience
• Chemistry experience (synthetic, computational, or medicinal)
• Computational Biology/Biophysics experience (e.g., MD, molecular docking, CADD)
• Structural biology experience (e.g., X-Ray Crystallography, NMR…)

• Gain direct mentoring from doctoral level mentors and co-workers.
• Dedicated self-discovery time to further a scientific/ engineering skill/ interest.
• Work together to make a positive contribution to patients by revolutionising the pharmaceutical industry through AI-driven discovery.
• The opportunity to acquire valuable skills, work on problems that matter, and learn from world-class technological and scientific leaders.
• Opportunity to join an inclusive, collaborative and intellectually stimulating culture
• Our team’s health and well-being is important to us we offer a generous holiday allowance, provide flexible working and remote working to encourage all of our team to manage their own work, time and life along with wellbeing and mindfulness support.
• When you are in the office, you will have access to a kitchen stocked with an endless supply of food for all employees. Along with access plenty of break out areas so you can get to know the people you are working with. Some of the best ideas start with a coffee break! 

• Act as the key link between Exscientia scientists and global CROs to ensure delivery of outsourced work in accordance with requirements and contractual obligations.
• Lead continuous improvement activities, applying problem solving skills to identify workflow efficiencies and implement technology solutions to enhance processes. Working with internal stakeholders to ensure learning is captured and incorporated into processes and practices.
• Support CRO governance to ensure these dovetail effectively with Exscientia drug project portfolio management.
• Measure delivery metrics by CRO partners and and communicate key internal stakeholders
• Act as point of contact/outsourcing expert for Exscientia

• Experience of drug discovery gained from working in either a pharmaceutical company, biotech or in a CRO
• Undergraduate science degree
• Excellent organisational and stakeholder management skills
• Experienced at issue resolution, problem solving and simplification of processes
• Strong communication skills

• Work together to make a positive contribution to patients by revolutionising the pharmaceutical industry through AI-driven discovery.
• We will work with you to kick-start or further grow your career – from funding for professional development and conference attendance, to the opportunity to acquire valuable skills, work on problems that matter, and learn from world-class technological and scientific leaders.
• Opportunity to join an inclusive, collaborative and intellectually stimulating culture
• We will work with you to provide a highly competitive compensation as we continue to grow and thrive.
• Our team’s health and well-being is important to us - we offer a generous holiday allowance, provide flexible working and remote working to encourage all of our team to manage their own work, time and life along with wellbeing and mindfulness support.
• When you are in the office, you will have access to a kitchen stocked with an endless supply of food for all employees along with access plenty of break out areas so you can get to know the people you are working with. Some of the best ideas start with a coffee break!
• Hear from our team about why they enjoy working here