Longevity Industry Jobs

Position Notes

• Estimated contract duration is 5 months.

Role Overview

• Key FP&A support role for the SG&A functions, which includes the development of annual budgets, periodic forecasts and long-range planning.
• Drive internal management of the report generation process and leverage the Oracle financial planning and budgeting system to enhance our analytical tools and support monthly reporting.
• Provide both operational and strategic financial support to help facilitate decision making.
• Partner with functional and department heads to ensure financial information (budget vs. actual) is provided in an accurate and timely manner, present key insights or trends that require attention and enable budget owners to manage their budgets.
• Collaborate with program and functional leaders to ensure consistency between corporate goals, program timelines, and program financial plans.
• Conduct ad hoc financial modeling to support business case development as well as cost and sensitivity analysis.
• Develop robust documentation.
• Support simplification process
• Independent self-starter with a continuous improvement mindset and the ability to work under pressure and meet deadlines.

Minimum Skills And Abilities

• Well organized and detail oriented.
• Outstanding communication skills (both written and oral) to effectively influence decision-making.
• Strong experience with ERP systems (e.g. SAP, Oracle) and planning and reporting tools
• Highly proficient in Excel, demonstrated expertise in creating and maintaining forecasts and complex financial models.
• Excellent problem solving and analytical skills.

Required Education

• Bachelor’s degree in finance or related field

Pay Transparency

The pay range that Magnit reasonably expects to pay for this position: $60.00-$80.00/hour. Benefits: Medical, Dental, Vision, 401K (provided minimum eligibility hours are met).

You will have the opportunity to contribute in the advanced drug discovery programs as well as early target identification group. You will be part of a core group to evaluate novel targets and identify predictive biomarkers to expand our drug discovery pipeline. This position offers the unique opportunity to directly impact a growing portfolio of targeted therapies in a fast-paced and innovative research environment. Your work will support Blueprint Medicines to bring the next-generation treatment to benefit the right patient.

What will you do?

• Maintain up to date with relevant literatures and identify creative ways to validate new targets.
• Independently carrying out cellular and molecular biology techniques, including gene targeting approaches and small molecule inhibition, to dissect mechanism of action.
• Develop, optimize, and proactively troubleshoot cellular screening assays.
• Design and execute key experiments for target validation and biomarker hypothesis generation.
• Experimental and intellectual contribution to cross-functional project teams.
• Perform other responsibilities as assigned.

What minimum qualifications do we require?

• PhD in oncology, molecular biology, cell biology, or related discipline.

What additional qualifications will make you a stronger candidate?

• Excellent time management skills, and comfortable with multi-tasking to thrive in a fast-paced environment and meet deadlines.
• Self-motivated creative scientist with a strong can-do attitude.
• Highly skilled in carrying out a wide range of state-of-the-art molecular and cellular biology techniques, including immunoblots, qPCR, mammalian cell culture, etc.
• Ability to learn and adapt to new technology as they become available.
• Ability to work effectively in a cross-functional team environment.
• Strong oral and written communication skills, as well as excellent documentation and organizational skills.
• Familiarity with standard software analytical tools, xlsx, Prism, etc.
• Commitment to our Core Values: Patients First, Thoughtfulness, Urgency, Trust, Optimism

Why Blueprint?

At Blueprint Medicines, we achieve impactful results because of our global crew of compassionate innovators – the Blue Crew. Through authentic relationships and our collective entrepreneurial spirit and action, we are each empowered to take ownership and execute with strategic prioritization. We put trust in our people to break through norms and conventions using their individual strengths and insights, which drives our success.

This is the place where the extraordinary becomes reality, and you could be part of it. Patients are waiting. Are you ready to make the leap?

COVID-19 Vaccination Requirement

As a biotechnology organization, it is our responsibility to do everything we can to safeguard the health and safety of our workforce, our communities, and the patients we serve. That is why, prior to their start date, new hires must provide confirmation that they are fully vaccinated against COVID-19, or receive approval by Blueprint for an exemption for health reasons contraindicating the vaccines or sincerely held religious beliefs. Accommodation requests for either of these reasons should be made to TotalRewards@blueprintmedicines.com.

Equity, Diversity, Inclusion and Affirmative Action

At Blueprint Medicines, we foster a culture of equity, diversity and inclusion. A proud Equal Employment Opportunity and Affirmative Action employer, we consider all qualified applicants without regard to race, color, sex, gender identity or expression, sexual orientation, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, or any other characteristic protected under applicable law. We are also an E-Verify Employer. We will make reasonable accommodations, absent undue hardship, for qualified individuals with known disabilities. If you are an individual with a disability in need of an accommodation with the application or recruiting process, please reach out to TotalRewards@blueprintmedicines.com.

For more information, please see our EEO-AA Policy Statement , the EEO Know Your Rights Poster , as well as our Pay Transparency Statement .

Blueprint Medicines is a global precision therapy company that invents life-changing therapies for people with cancer and blood disorders. Applying an approach that is both precise and agile, we create medicines that selectively target genetic drivers, with the goal of staying one step ahead across stages of disease. Since 2011, we have leveraged our research platform, including expertise in molecular targeting and world-class drug design capabilities, to rapidly and reproducibly translate science into a broad pipeline of precision therapies. Today, we are delivering approved medicines directly to patients in the United States and Europe, and we are globally advancing multiple programs for systemic mastocytosis, lung cancer and other genomically defined cancers, and cancer immunotherapy. 

The Director, Clinical Scientist will provide scientific support for all Clinical Development activities involving the conduct of clinical studies, including: clinical development plans, study design and feasibility, data collection requirements, analysis plans, preparation of meeting materials and internal/external presentations, lead development of key clinical documents (protocol/amendments, IB, CSR), safety and medical review, reporting of study results, and reviewing and summarizing relevant literature. Analyze and synthesize information to assess issues relating to protocol conduct and/or individual subject safety and assist in communicating a clear overview of trial results. The role will report to VP, Clinical Development and will collaborate with Clinical Pharmacology, Clinical Research, Translational Medicine, Regulatory Affairs, Biostatistics, Data Management and other functions as appropriate.

What will you do?

• Work closely with Medical Directors, Pharmacology, Discovery, external experts, and investigators to accumulate scientific and medical knowledge necessary to support clinical development plans and study designs and protocols
• Assist Medical Directors in creation of proposed concept sheets for clinical studies and author protocols through incorporation of input from both internal and external experts
• Leads the annual update of IB with input from Toxicology, Pharmacology, Safety, Regulatory
• Review and interpret biomarker data and help revise clinical development strategy based upon results
• Author clinical protocols, amendments and investigators brochures with input from internal and external experts as appropriate, clinical abstracts for presentations at conferences when appropriate and provide input into informed consents documents
• Drive and integrates clinical contribution to answering regulatory queries and other submissions related to studies
• Monitor and review along with the medical monitor safety and efficacy data in ongoing clinical trials; monitors GCP compliance with help of clinical operations and CRO
• Involved in high level data cleaning activities requiring interpretation and clinical judgment
• Involved in analysis of complex data for regulatory submissions, publications and design of studies and programs
• Attend scientific meetings to remain abreast of new developments within relevant areas and to interact with investigators, and advisors
• Work with investigative sites to answer protocol related questions, resolve study conduct and design issues
• Coach, mentor and supervise other Clinical Scientists
• Present data, protocol designs and other information at advisory boards, investigator meetings, site initiations and other internal and external settings
• Reviewer of CRFs, SAPs, TLFs, study manuals impacting endpoint assessment/data collection/analysis (ie, central imaging review charter, blinding plan, data transfer plans for central labs, etc.)
• Provide scientific and clinical development input into all other program documents in support of the development plan, including but not limited to informed consent forms (ICF), case report forms (CRF), statistical analysis plans (SAP), and clinical pharmacology/translational medicine plans
• Conduct literature and database research on providing background data for clinical trials, and regulatory documents as needed.

What minimum qualifications do we require?

• Degree in scientific/life sciences/clinical/nursing field
• Advanced degree required (M.S., PharmD, or Ph.D. )

What additional qualifications will make you a stronger candidate?

• 7+ years of clinical drug development experience
• Prior hematology or oncology drug development experience a plus
• Ability to work in a highly collaborative, matrix environment with the ability to manage through conflict resolution
• Excellent written and oral communication skills
• Strong analytical ability, detail oriented, and proficiency in data management a plus
• Commitment to our Core Values: Patients First, Thoughtfulness, Urgency, Trust, Optimism

Why Blueprint?

At Blueprint Medicines, we achieve impactful results because of our global crew of compassionate innovators – the Blue Crew. Through authentic relationships and our collective entrepreneurial spirit and action, we are each empowered to take ownership and execute with strategic prioritization. We put trust in our people to break through norms and conventions using their individual strengths and insights, which drives our success.

This is the place where the extraordinary becomes reality, and you could be part of it. Patients are waiting. Are you ready to make the leap?

COVID-19 Vaccination Requirement

As a biotechnology organization, it is our responsibility to do everything we can to safeguard the health and safety of our workforce, our communities, and the patients we serve. That is why, prior to their start date, new hires must provide confirmation that they are fully vaccinated against COVID-19, or receive approval by Blueprint for an exemption for health reasons contraindicating the vaccines or sincerely held religious beliefs. Accommodation requests for either of these reasons should be made to TotalRewards@blueprintmedicines.com.

Equity, Diversity, Inclusion and Affirmative Action

At Blueprint Medicines, we foster a culture of equity, diversity and inclusion. A proud Equal Employment Opportunity and Affirmative Action employer, we consider all qualified applicants without regard to race, color, sex, gender identity or expression, sexual orientation, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, or any other characteristic protected under applicable law. We are also an E-Verify Employer. We will make reasonable accommodations, absent undue hardship, for qualified individuals with known disabilities. If you are an individual with a disability in need of an accommodation with the application or recruiting process, please reach out to TotalRewards@blueprintmedicines.com.

For more information, please see our EEO-AA Policy Statement , the EEO Know Your Rights Poster , as well as our Pay Transparency Statement .

Blueprint Medicines is a global precision therapy company that invents life-changing therapies for people with cancer and blood disorders. Applying an approach that is both precise and agile, we create medicines that selectively target genetic drivers, with the goal of staying one step ahead across stages of disease. Since 2011, we have leveraged our research platform, including expertise in molecular targeting and world-class drug design capabilities, to rapidly and reproducibly translate science into a broad pipeline of precision therapies. Today, we are delivering approved medicines directly to patients in the United States and Europe, and we are globally advancing multiple programs for systemic mastocytosis, lung cancer and other genomically defined cancers, and cancer immunotherapy. 

Reporting to the Senior Medical Director or VP, Drug Safety and Pharmacovigilance, you will be responsible for the medical assessment of Individual Case Safety Reports (ICSRs) and drug safety information. You will actively assess and interpret safety data from multiple sources, including clinical trials, spontaneous and solicited reports, aggregate, and literature reports. Providing interpretation and summaries of drug safety information and input in the generation of safety reports (e.g., DSURs, PSUR and clinical safety assessments). You will serve as an integral part of a group of safety professionals, working in partnership with safety teams in Contract Research Organizations (CROs) and partners. You are a lifelong learner who will maintain medical knowledge as required by the role. Strong and current knowledge of drug safety, pharmacovigilance regulations, pharmacovigilance practices, safety surveillance and risk-management practices will be applied to transform hope into reality for patients globally.

What will you do?

• Provide medical expertise in the assessment of ICSRs and aggregate safety data.
• Lead the creation of aggregate safety reports including development safety update reports, periodic benefit risk evaluation reports, and provide medical input in review of new or existing safety documents to ensure compliance with relevant regulatory requirements, such as protocols, safety summaries and regulatory reports.
• Provide support to internal PV Operations.
• Effectively lead ongoing safety surveillance & detection activities, including the identification of new safety signals/emergent safety concerns to ensure timely assessment and communications.
• Serve as a medical resource for the generation and review of clinical trial protocols, informed consent forms (ICFs), investigator brochures (IBs) and other clinical documents as required.
• Contribute to the creation and/or updates to Risk Management Plans (RMPs) and the maintenance of the document.
• Develop and craft Standard Operating Procedures, Working Instructions, and other documentation.
• Build and deliver drug safety and Pharmacovigilance training programs.
• Collaborate with Global Regulatory Science and other relevant functions to ensure appropriate reporting of safety information to regulatory agencies and HCPs.
• Work in a cross-functional setting with Medical Directors and Clinical Research Scientists, and vendor clinical staff who provide medical monitoring support for ongoing clinical trials.
• Provide subject matter expertise to external vendors and partners.

What minimum qualifications do we require?

• 3- 5 years’ experience in Drug Safety/Pharmacovigilance in a pharmaceutical or biotech company, CRO or regulatory agency
• Medical Degree (MD) from recognized medical school with medical practice experience.

What additional qualifications will make you a stronger candidate?

• Strong understanding of US and EU drug safety regulations, CIOMS and ICH guidelines.
• Proven experience with medical safety assessments and monitoring activities.
• Proficiency with medical review of ICSRs, including expectedness assessments, causality assessments, narrative review and generation of Analysis of Similar Event and company comment statements, including benefit-risk assessment.
• Experience with safety data collection and interpretation originating from clinical trials and other sources (such as the literature, solicited and post-marketing environment)
• Preparation of aggregate reports (DSUR, PSUR/PBRER, PADER).
• Established proficiency preparing responses to Regulatory Authorities.
• Expertise with IND/NDA submissions including negotiations with Regulatory Authorities as part of marketing approval.
• Experience with developing and updating Reference Safety Information, including IB, Company Core Data Sheet (CCDS) and local labels.
• Ability to build positive relationships, collaborate, and influence across teams within Blueprint Medicines and outside partners.
• Excellent verbal, written and presentation skills.
• Commitment to our Core Values: Patients First, Thoughtfulness, Urgency, Trust, Optimism

Why Blueprint?

At Blueprint Medicines, we achieve impactful results because of our global crew of compassionate innovators – the Blue Crew. Through authentic relationships and our collective entrepreneurial spirit and action, we are each empowered to take ownership and execute with strategic prioritization. We put trust in our people to break through norms and conventions using their individual strengths and insights, which drives our success.

This is the place where the extraordinary becomes reality, and you could be part of it. Patients are waiting. Are you ready to make the leap?

COVID-19 Vaccination Requirement

As a biotechnology organization, it is our responsibility to do everything we can to safeguard the health and safety of our workforce, our communities, and the patients we serve. That is why, prior to their start date, new hires must provide confirmation that they are fully vaccinated against COVID-19, or be approved by Blueprint for an exemption for health reasons contraindicating the vaccines or sincerely held religious beliefs. Accommodation requests for either of these reasons should be made to TotalRewards@blueprintmedicines.com.

Equity, Diversity, Inclusion and Affirmative Action

At Blueprint Medicines, we foster a culture of equity, diversity and inclusion. A proud Equal Employment Opportunity and Affirmative Action employer, we consider all qualified applicants without regard to race, color, sex, gender identity or expression, sexual orientation, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, or any other characteristic protected under applicable law. We are also an E-Verify Employer. We will make reasonable accommodations, absent undue hardship, for qualified individuals with known disabilities. If you are an individual with a disability in need of an accommodation with the application or recruiting process, please reach out to TotalRewards@blueprintmedicines.com.

For more information, please see our EEO-AA Policy Statement , the EEO Know Your Rights Poster , as well as our Pay Transparency Statement .

Blueprint Medicines is a global precision therapy company that invents life-changing therapies for people with cancer and blood disorders. Applying an approach that is both precise and agile, we create medicines that selectively target genetic drivers, with the goal of staying one step ahead across stages of disease. Since 2011, we have leveraged our research platform, including expertise in molecular targeting and world-class drug design capabilities, to rapidly and reproducibly translate science into a broad pipeline of precision therapies. Today, we are delivering approved medicines directly to patients in the United States and Europe, and we are globally advancing multiple programs for systemic mastocytosis, lung cancer and other genomically defined cancers, and cancer immunotherapy. 

How will your role help us transform hope into reality?

Ensure impactful Omnichannel communication to all relevant audiences on disease awareness and product related information in line with overall business strategy for Germany at Blueprint Medicines.

What will you do?

•  Establish state-of-the-art omnichannel & digital expertise at Blueprint Medicines Germany
• Drive planning and implementation of omnichannel communication strategy at Blueprint Medicine Germany based on business needs.
• Build and execute omnichannel/digital projects, and operational action plans
• Monitor and identify trends, opportunities and threats in omnichannel marketing and integrate them into strategic and tactical plans. Always be up to date.
• Identify, brief and manage 3rd party agencies and cooperations within the context of omnichannel marketing activities
• Monitor and control marketing budgets, forecasts and expenses and assess the omnichannel mix to evaluate cost efficiency and results
• Liaising closely with product management to ensure alignment with all other commercial and product related activities and strategy
• Liaising closely with all support functions (including Medical, Regulatory, Commercial and International Marketing).
• Experience with Salesforce Marketing Cloud would be a plus
• Collating Competitor Intelligence from the market
• Define meaningful KPIs for tactics, build the necessary measurement tools and dashboards, monitor & report progress and impact.

What minimum qualifications do we require?

• University degree in Life Sciences or Business/Marketing
• 5+ years in pharmaceutical industry
• 2-3 years of experience in the role of product marketing/sales

What additional qualifications will make you a stronger candidate?

• Experience in digital / omnichannel marketing with proven track record in implementing and leading omnichannel projects
• Strong analytical skills and attention to detail
• Strong digital and direct marketing skills
• Sound knowledge of the regulatory framework in pharmaceutical industry
• Experience in project management
• Experience in leading 3rd parties e.g. agencies
• Excellent knowledge of GDPR regulations in Germany and EU
• Presentation/Communication skills
• Relationship building
• Adaptability
• Commercial awareness
• Commitment to our Core Values: Patients First, Thoughtfulness, Urgency, Trust, Optimism

Why Blueprint?

At Blueprint Medicines, we achieve impactful results because of our global crew of compassionate innovators – the Blue Crew. Through authentic relationships and our collective entrepreneurial spirit and action, we are each empowered to take ownership and execute with strategic prioritization. We put trust in our people to break through norms and conventions using their individual strengths and insights, which drives our success.

This is the place where the extraordinary becomes reality, and you could be part of it. Patients are waiting. Are you ready to make the leap?

Blueprint Medicines is a global precision therapy company that invents life-changing therapies for people with cancer and blood disorders. Applying an approach that is both precise and agile, we create medicines that selectively target genetic drivers, with the goal of staying one step ahead across stages of disease. Since 2011, we have leveraged our research platform, including expertise in molecular targeting and world-class drug design capabilities, to rapidly and reproducibly translate science into a broad pipeline of precision therapies. Today, we are delivering approved medicines directly to patients in the United States and Europe, and we are globally advancing multiple programs for systemic mastocytosis, lung cancer and other genomically defined cancers, and cancer immunotherapy. 

Blueprint Medicines is a global precision therapy company that invents life-changing therapies for people with cancer and hematologic disorders. Applying an approach that is both precise and agile, we create medicines that selectively target genetic drivers, with the goal of staying one step ahead across stages of disease. Since 2011, we have leveraged our research platform, including expertise in molecular targeting and world-class drug design capabilities, to rapidly and reproducibly translate science into a broad pipeline of precision therapies. Today, we are delivering approved medicines directly to patients in the United States and Europe, and we are globally advancing multiple programs for genomically defined cancers, systemic mastocytosis, and cancer immunotherapy.

Blueprint Medicines has built an integrated platform that combines genomics expertise with a novel kinase inhibitor library. Blueprint is also actively exploring novel modalities to inhibit kinase function through non-ATP competitive binders and/or degradation pathways as well as considering protein targets outside the kinases. To aid in our mission of rapidly developing highly selective compounds to address clear genomic drivers of disease, we are seeking a motivated scientist with expertise in cheminformatics and machine learning to join our Computational Chemistry group within the Drug Discovery team. This role is a 6-month contractor but with a potential temp-to-perm opportunity. In this role, the successful candidate will develop and apply state-of-the-art cheminformatics and machine learning models and tools to accelerate and improve molecule design and optimization cycles in drug discovery. The incumbent will be an integral part of a highly capable and collaborative team and work at the intersection of computational chemistry, data science, information technology and medicinal & biological chemistry.

Position Notes

• This is a Hybrid role, must be local to Cambridge Massachusetts.
• Estimated contract duration is 5 months.

Role Overview

• Develop, integrate, and apply cheminformatics/computational tools and workflows to improve existing infrastructure and acquire or create needed ones.
• Provide informatics and cheminformatics support to the functions within Chemical Sciences, drug discovery projects and new target development initiatives.
• Build and maintain infrastructure/data workflows to facilitate mining and integrating data from internal and external databases
• Design and apply state-of-the-art machine learning and cheminformatics algorithms for molecule generation, scoring and selection.
• Collaborate closely with the computational chemistry group and other cross-functional teams including Research IT, MedChem, BioChem, Compound Management, etc.
• Communicate scientific results internally and externally via presentations and publications.

Minimum Required Education

• A PhD with 1+ years OR master’s degree with 4+ years post-graduate experience (industry preferred) in cheminformatics, computational chemistry, computer/data science, or related fields. Pay rate commensurate with experience.

Minimum Required Skills And Abilities

• Strong hands-on experience with one or more programming, scripting, or querying languages (e.g. Python, R, Java, SQL/NoSQL, etc) and cheminformatics toolkits (such as RDKit, ChemAxon, DeepChem, OEChem, etc).
• Technical expertise in developing cheminformatics protocols using workflow tools – experience with KNIME and Schrödinger eco-system of computational software preferred.
• Working experience with machine learning and deep learning architectures such as PyTorch, TensorFlow, Keras, Scikit-Learn is a plus.
• A basic knowledge of drug discovery processes, medicinal chemistry, chemical biology and DMPK is encouraged.

Pay Transparency

The pay range that Magnit reasonably expects to pay for this position: $67.50-$90.00/hour. Benefits: Medical, Dental, Vision, 401K (provided minimum eligibility hours are met).

As a member of Blueprint Medicine’s Commercial Sales Team, the Area Business Manager will play a critical role in the successful promotion of approved drugs to targeted accounts including, but not limited to, large group practices, academic centers, hospital systems, community networks, and IDNs in an assigned territory. You will represent Blueprint Medicine’s portfolio of precision therapies in Oncology and Rare Diseases with a focus and expertise in Lung, Thyroid and Hematologic malignancies. You will have expert knowledge of oncology market dynamics including key customers and accounts with a focus on delivering impactful therapies and transforming the lives of appropriate patients. You will report to the Regional Business Director and be a key member of an efficient, effective and highly collaborative field team.

What will be your responsibilities?

• Apply strong clinical knowledge to effectively educate on relevant products and disease states to oncologists and the broader care team in academic and community practice settings
• Exhibit a patient focused approach while delivering educational resources and programs to assist with effective patient care
• Build and maintain relationships with key customers, involving cross-functional partners as needed to manage key relationships of national and/or regional relevance
• Collaborate closely with field-based colleagues (Regional Marketing Executives, Precision Medicine Liaisons, National Account Executives, and MSLs). Builds relationships and maintains effective communication with internal partners
• Develop effective business plans sought at achieving set objectives
• Proactively identify new opportunities and apply customer insights to develop, execute and refine approaches.
• Use analytical tools to understand business trends and meet or exceed target key performance metrics
• Represent Blueprint Medicines at congresses and local / regional medical meetings
• Ability to travel within the US on a regular basis, which may include overnight and weekend travel
• Follow regulatory guidelines, public policies/guidelines, and corporate policies and procedures

What basic qualifications do we require?

• BA/BS degree required
• 5+ years’ experience in biotech/ pharma sales calling on relevant specialists

What additional qualifications are we seeking?

• Demonstrated success across multiple drug launches in applicable specialty markets
• Strong clinical background in applicable specialties is required, oncology and/ or rare disease experience is preferred
• Understanding of oral targeted therapies with a requisite diagnostic component and ability to navigate in complex market access environments
• Ability to navigate in complex market access environments
• Strong oral and written communication skills; Ability to speak Spanish fluently is a plus
• Robust analytical and problem-solving skills, ability to identify and act on creative solutions
• Ability to establish credibility, connect the dots and align multiple partners to pioneer the adoption of new products, methods and technologies
• A great teammate able to collaborate effectively with a broad range of collaborators, gain consensus and act independently in a fast-paced, ambitious environment
• Flexibility and the ability to plan and nimbly adapt to changing market conditions
• Motivated by patient focus, urgency and personal dedication to high performance, results and compliance
• Possesses integrity and outstanding work ethic
• Commitment to Blueprint Medicines’ Core Values: Patients First, Thoughtfulness, Urgency, Trust, Optimism

COVID-19 Vaccination Requirement

As a biotechnology organization, it is our responsibility to do everything we can to safeguard the health and safety of our workforce, our communities, and the patients we serve. That is why, prior to their start date, new hires must provide confirmation that they are fully vaccinated against COVID-19, or receive approval by Blueprint for an exemption for health reasons contraindicating the vaccines or sincerely held religious beliefs. Accommodation requests for either of these reasons should be made to TotalRewards@blueprintmedicines.com.

Equity, Diversity, Inclusion and Affirmative Action

At Blueprint Medicines, we foster a culture of equity, diversity and inclusion. A proud Equal Employment Opportunity and Affirmative Action employer, we consider all qualified applicants without regard to race, color, sex, gender identity or expression, sexual orientation, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, or any other characteristic protected under applicable law. We are also an E-Verify Employer. We will make reasonable accommodations, absent undue hardship, for qualified individuals with known disabilities. If you are an individual with a disability in need of an accommodation with the application or recruiting process, please reach out to TotalRewards@blueprintmedicines.com.

For more information, please see our EEO-AA Policy Statement , the EEO Know Your Rights Poster , as well as our Pay Transparency Statement .

Blueprint Medicines is a global precision therapy company that invents life-changing therapies for people with cancer and blood disorders. Applying an approach that is both precise and agile, we create medicines that selectively target genetic drivers, with the goal of staying one step ahead across stages of disease. Since 2011, we have leveraged our research platform, including expertise in molecular targeting and world-class drug design capabilities, to rapidly and reproducibly translate science into a broad pipeline of precision therapies. Today, we are delivering approved medicines directly to patients in the United States and Europe, and we are globally advancing multiple programs for systemic mastocytosis, lung cancer and other genomically defined cancers, and cancer immunotherapy.

This position reports into the Associate Director International Medical Affairs Operations and will provide support to a broad range of activities essential for the seamless execution of the International Medical Affairs strategic plan. The International Medical Affairs Operations Coordinator has responsibilities covering procurement, events coordination, budget tracking, materials approval workflows, vendor management, and onboarding. When required, the position will also provide support to the Medical Affairs departments of several European countries.

The successful applicant will be highly organized with good project management skills, strong attention to detail and will possess a solid understanding medical affairs and field medical operations, event planning, finance operations and budget tracking for successful operational support of international medical teams. This is a contract role with the possibility for internalization after one year in the role.

What will you do?

Responsibilities of this position involve the day-to-day support of International Medical Affairs activities in collaboration with a dynamic cross-functional team across multiple countries.

• In collaboration with business owners, coordinate the raising and tracking of purchase orders and associated engagement agreements
• Working closely with Accounts Payable to manage invoicing receipt and reconciliation
• Generate financial reports to assist with the tracking of spend vs plan
• Single point of contact for the coordination of the uploading and review of marketing and medical materials according to system workflows
• With input from relevant internal stakeholders, project manage internal (e.g. department offsite) and external (e.g. advisory board) meetings
• Creation of reports and dashboards from CRM interaction and insights data for internal communication
• Working closely with onboarding manager, develop and track onboarding plans for new employees, as well as assist with required system access and training
• Maintain information in line with compliance retention and reporting requirements including; fair market value, transparency, anti-bribery etc.
• Working with the preferred vendor, manage ordering, inventory, distribution, and retrieval of Regional and Local Medical field materials
• Provide administrative support to the VP International Medical Affairs, as required

What minimum qualifications do we require?

• Bachelor’s degree or Diploma in business and/or science with 3-5 years of related experience within the pharmaceutical industry.

What additional qualifications will make you a stronger candidate?

• Experience in vendor engagement and oversight
• Experience in field medical operations, event planning, finance operations and budget tracking
• High level of proficiency with Microsoft Word, Excel, Outlook, Teams
• Familiarity with the role of country affiliates.
• Strong interpersonal, presentation and communication skills and demonstrated ability to work collaboratively in a dynamic, team-oriented environment
• Creative problem-solving skills
• Positive, solutions-oriented mindset
• Demonstrated self-starter and team player with strong interpersonal skills
• Adept, nimble, energetic and comfortable in a fast-paced, dynamic and collaborative environment
• Capable of taking a hands-on approach and willing to “roll up one’s sleeves.”
• Motivated self-starter who will thrive in a fast-paced company environment.
• Creative problem solver with excellent communication.
• Strong interpersonal and organizational skills are needed, with a high degree of attention to detail. Ability to interact well with individuals at all team levels.
• Knowledge of country regulations and knowledge of relevant global regulatory requirements, a plus.
• Commitment to our Core Values: Patients First, Thoughtfulness, Urgency, Trust, Optimism

Why Blueprint?

At Blueprint Medicines, we achieve impactful results because of our global crew of compassionate innovators – the Blue Crew. Through authentic relationships and our collective entrepreneurial spirit and action, we are each empowered to take ownership and execute with strategic prioritization. We put trust in our people to break through norms and conventions using their individual strengths and insights, which drives our success.

This is the place where the extraordinary becomes reality, and you could be part of it. Patients are waiting. Are you ready to make the leap?

Blueprint Medicines is a global precision therapy company that invents life-changing therapies for people with cancer and blood disorders. Applying an approach that is both precise and agile, we create medicines that selectively target genetic drivers, with the goal of staying one step ahead across stages of disease. Since 2011, we have leveraged our research platform, including expertise in molecular targeting and world-class drug design capabilities, to rapidly and reproducibly translate science into a broad pipeline of precision therapies. Today, we are delivering approved medicines directly to patients in the United States and Europe, and we are globally advancing multiple programs for systemic mastocytosis, lung cancer and other genomically defined cancers, and cancer immunotherapy. 

This is an excellent opportunity for a physician with experience in industry or academic hematology / oncology clinical development to work within a rapidly growing company dedicated to precision medicine. The Director/Senior Director, Clinical Development is responsible for designing and executing clinical studies, helping to build the clinical development plan for new compounds, and paving a path towards regulatory approval. The Blueprint Medicines pipeline provides opportunities to work in early clinical development where the physician will work closely with scientists in discovery research and translational medicine, as well as non-clinical safety, DMPK/clinical pharmacology, biostatistics, clinical operations, regulatory and commercial development. There are also opportunities to engage in peri- and post-approval studies across the lifecycle of a drug. The physician will also lead and participate in teleconferences with academic study investigators, advisory meetings with opinion leaders, and interactions with Health Authorities. The physician will interact closely with the company management team. A genuine interest and understanding of the science supporting the Blueprint Medicines pipeline, an ability to work collaboratively in a highly matrixed, multidisciplinary team setting, and a commitment to developing new treatments for patients with cancer and hematologic disorders are critical for success.

What will you do?

• Provide strategic leadership in the existing and planned clinical programs to support global filings
• Supervise the design and writing of oncology clinical study protocols from first-in-human phase 1 through phase 2 and phase 3 pivotal studies that will support regulatory approvals
• Medical monitor for multiple ongoing clinical trials, including evaluation of clinical and laboratory data, assessing safety, responsibility for dose escalation decisions in phase 1, and assessing early pharmacodynamics and clinical signals of activity
• Coordinate activities with translational medicine colleagues to develop biomarker strategies for and interpret data generated from clinical trials
• Write clinical sections of key documents, including Investigator’s Brochures, IND summary documents, CTAs for initiation of studies ex-US, responses to questions from regulatory authorities, IRBs and ethics committees, and NDAs
• Provide medical review, assessment and interpretation of all clinical data reported in clinical study reports to ensure that the data are correct and presented with the appropriate medical interpretation
• Attend and support clinical site initiation visits
• Work closely with Blueprint R&D team, regulatory affairs, and consultants to assure timely filing of all clinical applications
• Work closely with Pharmacovigilance on development of Risk Management Plans
• Ensure consistent practices with the highest ethical standards in compliance with internal SOPs, local regulations and laws
• Serve as the clinical face of the company both internally and externally, including the scientific community and key opinion leaders

What minimum qualifications do we require?

• An M.D., D.O., N.P., P.A. or comparable advanced practice degree
• 2-5+ years of proven ability in the biotechnology or pharmaceutical industry including direct experience leading, OR thorough understanding of the drug development process from IND through NDA, including novel clinical study designs, application of companion diagnostics for patient selection, clinical operations and pharmacovigilance
• Medical Director – 2-3 years industry experience
• Senior Medical Director – 3-5+ years industry experience

What additional qualifications will make you a stronger candidate?

• Experience in adult or pediatric oncology, hematology, or rare diseases
• Expertise in solid tumor oncology, particularly Breast Oncology
• Expertise in Lung Cancer
• Strong leadership skills and proven biopharmaceutical industry experience developing, planning, designing and executing early and late stage programs.
• Experience leading the clinical aspects of interactions with Regulatory Authorities, such as FDA and EMA.
• Experience presenting to a wide variety of audiences including internal teams and medical/scientific communities
• Experience with high-complexity first-in-human studies is highly desired
• Expertise in precision oncology and targeted therapies
• Translational research experience, including candidates with M.D./Ph.D.s, are highly desired
• Commitment to Blueprint Medicines’ Core Values: Patients First, Thoughtfulness, Urgency, Trust, Optimism
• Commitment to our Core Values: Patients First, Thoughtfulness, Urgency, Trust, Optimism

Why Blueprint?

At Blueprint Medicines, we achieve impactful results because of our global crew of compassionate innovators – the Blue Crew. Through authentic relationships and our collective entrepreneurial spirit and action, we are each empowered to take ownership and execute with strategic prioritization. We put trust in our people to break through norms and conventions using their individual strengths and insights, which drives our success.

This is the place where the extraordinary becomes reality, and you could be part of it. Patients are waiting. Are you ready to make the leap?

COVID-19 Vaccination Requirement

As a biotechnology organization, it is our responsibility to do everything we can to safeguard the health and safety of our workforce, our communities, and the patients we serve. That is why, prior to their start date, new hires must provide confirmation that they are fully vaccinated against COVID-19, or be approved by Blueprint for an exemption for health reasons contraindicating the vaccines or sincerely held religious beliefs. Accommodation requests for either of these reasons should be made to TotalRewards@blueprintmedicines.com.

Equity, Diversity, Inclusion and Affirmative Action

At Blueprint Medicines, we foster a culture of equity, diversity and inclusion. A proud Equal Employment Opportunity and Affirmative Action employer, we consider all qualified applicants without regard to race, color, sex, gender identity or expression, sexual orientation, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, or any other characteristic protected under applicable law. We are also an E-Verify Employer. We will make reasonable accommodations, absent undue hardship, for qualified individuals with known disabilities. If you are an individual with a disability in need of an accommodation with the application or recruiting process, please reach out to TotalRewards@blueprintmedicines.com.

For more information, please see our EEO-AA Policy Statement , the EEO Know Your Rights Poster , as well as our Pay Transparency Statement .

Blueprint Medicines is a global precision therapy company that invents life-changing therapies for people with cancer and blood disorders. Applying an approach that is both precise and agile, we create medicines that selectively target genetic drivers, with the goal of staying one step ahead across stages of disease. Since 2011, we have leveraged our research platform, including expertise in molecular targeting and world-class drug design capabilities, to rapidly and reproducibly translate science into a broad pipeline of precision therapies. Today, we are delivering approved medicines directly to patients in the United States and Europe, and we are globally advancing multiple programs for systemic mastocytosis, lung cancer and other genomically defined cancers, and cancer immunotherapy.

The Director, Corporate Counsel is responsible for partnering on a broad range of corporate legal matters for Blueprint Medicines’ commercial products and product candidates, including reviewing advertising, promotional, external communications, and medical materials, and providing strategic advice on new initiatives and programs. The Director, Corporate Counsel, will leverage their understanding of Blueprint Medicines’ business, biopharmaceutical companies, and the legal and regulatory framework relevant to our industry to provide thoughtful, solution-oriented legal advice that furthers the company’s business strategy and protects the company’s interests. Reporting to the Vice President, Corporate Legal Affairs, the Director, Corporate Counsel, will partner with teams in the U.S. and Europe. This position offers the opportunity to work in a dynamic environment where initiative, creative thinking and teamwork are valued!

What will you do?

• Serve as legal reviewer on promotional and medical review teams and partner with Commercial, Medical Affairs, and Regulatory Affairs to help ensure compliance, consistency, and accuracy in connection with promotional, medical, and disease awareness materials, publications, scientific and medical meeting materials, training materials, and materials for advisory boards and market research.
• Advise Commercial and Medical Affairs in implementation of new programs and initiatives in compliance with applicable laws, regulations and industry standards.
• Provide legal advice related to materials and initiatives from the Patient Advocacy, Precision Medicine, Clinical Development, and Clinical Operations teams.
• Work collaboratively as a member of cross-functional teams to review other external and internal communication materials, including press releases, conference call scripts, corporate presentations, social media postings, website content, and webinar materials.
• Partner with other members of the Legal and Compliance department as requested to establish and implement periodic risk assessments and audits to identify potential areas of compliance vulnerability and risk. Assist with developing and conducting trainings or other educational materials for internal teams , as requested.
• Help support transactional, contracting, and other business development initiatives, including drafting, reviewing, and negotiating agreements and transaction-related documents, as needed.
• Partner with Compliance, Medical Affairs, Patient Advocacy, Commercial, and other colleagues as requested on review of sponsorships, grants, and donations.
• Support Legal & Compliance department’s initiatives as requested and represent the department on cross-functional teams, company-wide initiatives or committees, and special projects, as assigned.
• Maintain a working knowledge of applicable laws, regulations, enforcement actions, advisory comments, and policy issues to identify emerging trends and risks. Keep department colleagues, senior management and cross-functional partners informed of trends and risks and help implement related policies, procedures, and training programs.
• This position may require periodic domestic and international travel and does not have managerial responsibility or budgetary discretion.

What minimum qualifications do we require?

• JD from an accredited law school
• Member in good standing of the Massachusetts bar
• 5-8+years of legal experience in the biopharmaceutical industry at a large law firm and/or in an in-house legal department

What additional qualifications will make you a stronger candidate?

• A thorough understanding of healthcare laws and regulations and corporate governance issues related to development and commercialization of biopharmaceutical products, including without limitation US Federal healthcare program requirements under the Food, Drug and Cosmetic Act, the False Claims Act, the Anti-Kickback Statute, Office of Inspector General guidelines and opinions, advisory options and letters, the Sunshine Act, the Foreign Corrupt Practices Act, the U.K Bribery Act, the Health Insurance Portability and Accountability Act, and the General Data Protection Regulation
• Sound judgment, high integrity and commitment to ethical conduct
• Excellent analytical, written, and verbal communication skills
• Excellent professionalism and interpersonal skills
• Prior experience advising on advertising and promotional matters as a member of an in-house legal department of a commercial-stage biopharmaceutical company strongly preferred
• Prior experience with drafting and negotiating collaboration and licensing agreements in the biotechnology industry a plus
• Ability to work collaboratively as a member of cross-functional teams with a pragmatic approach and a positive attitude in a results-driven, highly accountable environment
• Ability to lead and think beyond “legal” and to lead cross-functional innovative initiatives
• Ability to communicate with colleagues at all levels of the organization with both the self-confidence necessary to set forth opinions even in the face of contrary views and the humility needed to be receptive to the ideas and opinions of others
• Demonstrated ability to think strategically and pay close attention to detail
• Strong project management skills and ability to handle multiple responsibilities simultaneously and still meet high quality and timeliness standards
• Self-motivated and independent team member who constantly seeks, designs, and implements improvements
• Ability to effectively and efficiently manage outside counsel (on the limited occasions when used) and adhere to a budget
• Commitment to Blueprint Medicines’ Core Values: Patients First, Thoughtfulness, Urgency, Trust, Optimism

Why Blueprint?

At Blueprint Medicines, we achieve impactful results because of our global crew of compassionate innovators – the Blue Crew. Through authentic relationships and our collective entrepreneurial spirit and action, we are each empowered to take ownership and execute with strategic prioritization. We put trust in our people to break through norms and conventions using their individual strengths and insights, which drives our success.

This is the place where the extraordinary becomes reality, and you could be part of it. Patients are waiting. Are you ready to make the leap?

COVID-19 Vaccination Requirement

As a biotechnology organization, it is our responsibility to do everything we can to safeguard the health and safety of our workforce, our communities, and the patients we serve. That is why, prior to their start date, new hires must provide confirmation that they are fully vaccinated against COVID-19, or be approved by Blueprint for an exemption for health reasons contraindicating the vaccines or sincerely held religious beliefs. Accommodation requests for either of these reasons should be made to TotalRewards@blueprintmedicines.com.

Equity, Diversity, Inclusion and Affirmative Action

At Blueprint Medicines, we foster a culture of equity, diversity and inclusion. A proud Equal Employment Opportunity and Affirmative Action employer, we consider all qualified applicants without regard to race, color, sex, gender identity or expression, sexual orientation, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, or any other characteristic protected under applicable law. We are also an E-Verify Employer. We will make reasonable accommodations, absent undue hardship, for qualified individuals with known disabilities. If you are an individual with a disability in need of an accommodation with the application or recruiting process, please reach out to TotalRewards@blueprintmedicines.com.

For more information, please see our EEO-AA-Policy-Statement , the EEO Poster and its Supplement , as well as our Pay Transparency Statement .

Blueprint Medicines is a global precision therapy company that invents life-changing therapies for people with cancer and blood disorders. Applying an approach that is both precise and agile, we create medicines that selectively target genetic drivers, with the goal of staying one step ahead across stages of disease. Since 2011, we have leveraged our research platform, including expertise in molecular targeting and world-class drug design capabilities, to rapidly and reproducibly translate science into a broad pipeline of precision therapies. Today, we are delivering approved medicines directly to patients in the United States and Europe, and we are globally advancing multiple programs for systemic mastocytosis, lung cancer and other genomically defined cancers, and cancer immunotherapy. 

The Senior Manager, Compliance Operations is a meaningful role responsible for leading certain day-to-day operations of the healthcare law Compliance Team within the Legal and Compliance Department. The role will collaborate with all members of the Compliance team based in the US and Europe as well as representatives from other functions to ensure an integrated approach to Compliance and will support the ongoing development, implementation, and continuous improvement of Blueprint Medicines’ Compliance Program. This position will report to the Vice President, Compliance & Ethics.

What will you do?

• Manage all healthcare law compliance data analytics and reporting processes, including presenting findings to senior leadership and other internal partners to help identify and understand potential areas of compliance vulnerability, develop preventative and corrective action plans, as appropriate, and enable continuous improvement
• Conduct risk assessments applying data analytics as well as interviews to help identify organizational risk
• Manage the US monitoring program which includes the development of live, remote, and transactional monitoring processes, procedures, and critical metrics
• Lead all aspects of the implementation and management of Compliance IT solutions including the hotline, external funding system, and HCP engagement systems and/or processes
• Regularly evaluate and improve compliance processes and controls to drive operational efficiency and effectiveness
• Key Compliance partner in assisting Finance in administering the transparency program in accordance with US Federal and State reporting requirements
• Assist with preparing policies, procedures and delivering trainings, as requested
• Deliver trainings, as requested
• Participate in other Compliance Program projects and department or company initiatives
• Act as a department representative on cross-functional teams, as assigned
• Ability to recognize compliance risk and develop workable strategies to mitigate such risk

What minimum qualifications do we require?

• Bachelors’ degree from an accredited school required: preferably in accounting, finance, law, business management, or a related field plus proven 3-5 years' of experience
• Strong operational and data analytics background and solid understanding of U.S. laws, regulations, and guidance applicable to the pharmaceutical industry including, but not limited to, fraud and abuse laws, anti-bribery and corruption laws, pharmaceutical marketing and transparency reporting

What additional qualifications will make you a stronger candidate?

• Sound judgment, high integrity, and dedication to ethical conduct.
• Ability to work collaboratively as a member of cross-functional teams with a pragmatic approach and a positive demeanor in a results-driven, highly accountable environment.
• Ability to connect with colleagues at all levels of the organization with both the self-confidence necessary to set forth opinions even in the face of contrary views and the humility needed to be receptive to the ideas and opinions of others.
• Demonstrated ability to think strategically and pay close attention to detail.
• Self-motivated and independent team member who constantly seeks, designs, and implements improvements.
• Strong project management skills and ability to balance multiple responsibilities simultaneously and still meet high quality and timeliness standards under pressure
• In-house experience at a biotechnology or pharmaceutical company or pharma/biotech consulting
• Dedication to Blueprint Medicines’ Core Values: Patients First, Thoughtfulness, Urgency, Trust, Optimism.

Why Blueprint?

At Blueprint Medicines, we achieve impactful results because of our global crew of compassionate innovators – the Blue Crew. Through authentic relationships and our collective entrepreneurial spirit and action, we are each empowered to take ownership and execute with strategic prioritization. We put trust in our people to break through norms and conventions using their individual strengths and insights, which drives our success.

This is the place where the extraordinary becomes reality, and you could be part of it. Patients are waiting. Are you ready to make the leap?

COVID-19 Vaccination Requirement

As a biotechnology organization, it is our responsibility to do everything we can to safeguard the health and safety of our workforce, our communities, and the patients we serve. That is why, prior to their start date, new hires must provide confirmation that they are fully vaccinated against COVID-19, or be approved by Blueprint for an exemption for health reasons contraindicating the vaccines or sincerely held religious beliefs. Accommodation requests for either of these reasons should be made to TotalRewards@blueprintmedicines.com.

Equity, Diversity, Inclusion and Affirmative Action

At Blueprint Medicines, we foster a culture of equity, diversity and inclusion. A proud Equal Employment Opportunity and Affirmative Action employer, we consider all qualified applicants without regard to race, color, sex, gender identity or expression, sexual orientation, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, or any other characteristic protected under applicable law. We are also an E-Verify Employer. We will make reasonable accommodations, absent undue hardship, for qualified individuals with known disabilities. If you are an individual with a disability in need of an accommodation with the application or recruiting process, please reach out to TotalRewards@blueprintmedicines.com.

For more information, please see our EEO-AA-Policy-Statement , the EEO Poster and its Supplement , as well as our Pay Transparency Statement .

Blueprint Medicines is a global precision therapy company that invents life-changing therapies for people with cancer and blood disorders. Applying an approach that is both precise and agile, we create medicines that selectively target genetic drivers, with the goal of staying one step ahead across stages of disease. Since 2011, we have leveraged our research platform, including expertise in molecular targeting and world-class drug design capabilities, to rapidly and reproducibly translate science into a broad pipeline of precision therapies. Today, we are delivering approved medicines directly to patients in the United States and Europe, and we are globally advancing multiple programs for systemic mastocytosis, lung cancer and other genomically defined cancers, and cancer immunotherapy. 

As the Director of Supply Planning and Logistics at Blueprint, you will drive our commercial operations strategy, optimize supply planning and product launch readiness, and oversee global logistics across both clinical and commercial portfolio. Co-leading long-term supply chain initiatives with relevant internal stakeholders, you will enhance our supply chain design to support continued growth, product life cycle management, and development programs in oncology and hematology. With expertise in supply chain design and infrastructure, product life cycle management, Sales and Operations Planning, manufacturing, packaging, relationship management, and compliance with applicable laws and regulations, you will lead the Planning and Logistics team to Blueprint’s continued success.

You will also lead strategic projects, foster effective relationships, and drive infrastructure enhancements. Joining our Supply Chain function means being part of a team that delivers innovative treatments worldwide, making a meaningful impact on patients' lives.

This role is based in Cambridge, MA and reports to the VP of Supply Chain & Strategic Sourcing.

What will you do?

• Lead the Planning and Logistics team, ensuring strategic vision, product supply risk mitigation, and operational execution.
• Oversee relationship management with Blueprint's 3PL organization for the US market, while collaborating closely with internal functions for communication and relationship oversight with select CDMOs and Commercial Packagers.
• Serve as the main connection between Blueprint's Supply Chain and Commercial teams, as well as Finance and Accounting teams, regarding budgeting, long range planning, inventory planning and month-end reporting.
• Develop commercial product launch plans aligned with corporate objectives and represent Technical Operations in launch-related activities.
• Assume business ownership for validated ERP Inventory Management module within Oracle
• Provide support in various aspects of commercial supply chain strategy and risk mitigation.
• Lead Blueprint's Technical Operations initiative, assessing long-term needs and designing commercial supply chains for multiple programs in clinical development.

What minimum qualifications do we require?

• 10+ years of relevant industry experience with deep understanding of all aspects of commercial supply chain, Planning, S&OP, and global logistics
• Scientific bachelor's degree desired with MBA strongly preferred

What additional qualifications will make you a stronger candidate?

• Deep understanding of relevant regulatory requirements and global guidance governing commercial supply chain
• Demonstrated experience working in a complex, multifunctional, fast paced, global environment
• Excellent organizational, planning, and interpersonal skills
• Strong business and financial acumen and decision-making skills required to work with third-party manufacturers/packagers as well as internal colleagues
• Demonstrate a proactive and innovative mindset, taking ownership of opportunities and driving them to fruition. Embrace a risk-taking attitude and seize new possibilities in a dynamic, fast-paced environment.
• Take full responsibility for assigned tasks and projects, ensuring their successful completion. Demonstrate a results-oriented approach, accountability, and a commitment to delivering high-quality outcomes.
• Exhibit strong prioritization skills to effectively allocate time, resources, and effort. Identify and focus on key objectives, making strategic decisions that align with organizational goals.
• Establish and nurture authentic relationships with internal and external stakeholders, fostering collaboration, trust, and open communication.
• Leverage leadership and management skills to drive team performance and development, empowering individuals to reach their full potential and achieve collective goals.
• Commitment to our Core Values: Patients First, Thoughtfulness, Urgency, Trust, Optimism

Why Blueprint?

At Blueprint Medicines, we achieve impactful results because of our global crew of compassionate innovators – the Blue Crew. Through authentic relationships and our collective entrepreneurial spirit and action, we are each empowered to take ownership and execute with strategic prioritization. We put trust in our people to break through norms and conventions using their individual strengths and insights, which drives our success.

This is the place where the extraordinary becomes reality, and you could be part of it. Patients are waiting. Are you ready to make the leap?

COVID-19 Vaccination Requirement

As a biotechnology organization, it is our responsibility to do everything we can to safeguard the health and safety of our workforce, our communities, and the patients we serve. That is why, prior to their start date, new hires must provide confirmation that they are fully vaccinated against COVID-19 or be approved by Blueprint for an exemption for health reasons contraindicating the vaccines or sincerely held religious beliefs. Accommodation requests for either of these reasons should be made to TotalRewards@blueprintmedicines.com.

Equity, Diversity, Inclusion and Affirmative Action

At Blueprint Medicines, we foster a culture of equity, diversity and inclusion. A proud Equal Employment Opportunity and Affirmative Action employer, we consider all qualified applicants without regard to race, color, sex, gender identity or expression, sexual orientation, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, or any other characteristic protected under applicable law. We are also an E-Verify Employer. We will make reasonable accommodations, absent undue hardship, for qualified individuals with known disabilities. If you are an individual with a disability in need of an accommodation with the application or recruiting process, please reach out to TotalRewards@blueprintmedicines.com.

For more information, please see our EEO-AA Policy Statement , the EEO Poster and its Supplement , as well as our Pay Transparency Statement .

Blueprint Medicines is a global precision therapy company that invents life-changing therapies for people with cancer and blood disorders. Applying an approach that is both precise and agile, we create medicines that selectively target genetic drivers, with the goal of staying one step ahead across stages of disease. Since 2011, we have leveraged our research platform, including expertise in molecular targeting and world-class drug design capabilities, to rapidly and reproducibly translate science into a broad pipeline of precision therapies. Today, we are delivering approved medicines directly to patients in the United States and Europe, and we are globally advancing multiple programs for systemic mastocytosis, lung cancer and other genomically defined cancers, and cancer immunotherapy.

The Laboratory Animal Resources group at Blueprint Medicines is seeking a highly motivated, scientifically creative, and collaborative Scientist I/II, In Vivo Pharmacology, to work in a fast-paced environment within a cross-functional team. Laboratory Animal Resources (LAR) at Blueprint Medicines is an organization responsible for providing in vivo resources to enable drug discovery objectives relevant to pharmacology, DMPK, biopharmaceutics, tolerability, and translational medicine. LAR comprises an internal rodent vivarium, hands-on in vivo scientific staff, husbandry technicians, and an external attending veterinarian. The group is expanding its role to include responsibility for ex vivo cell and tissue work as well as management and oversight of external in vivo pharmacology studies at CROs. As Scientist I/II, you will be a key team member within the In Vivo Pharmacology group and the broader Quantitative Pharmacology and Drug Safety organization. Your responsibilities will include hands-on in vivo pharmacology model development, study execution, ex vivo work, and data interpretation to support Blueprint’s pipeline across various disease areas. In this fast-paced high impact role, you will have the opportunity to contribute scientifically to programs at various discovery and development stages.

What will you do?

• Design, execute, and interpret in vivo pharmacology studies in rodents to evaluate the activities of small molecule drug candidates, investigate their mechanisms of action, and explore novel therapeutic hypotheses
• Work seamlessly with project teams and LAR to design and plan in-house pharmacology activities
• Perform ex vivo cell and tissue work, including but not limited to flow cytometry, ELISA, western blot, and quantitative RT-PCR
• Regularly analyze, document, and report in vivo and ex vivo data
• Regularly participate in project team meetings and present in vivo pharmacology research
• Manage in vivo pharmacology studies being performed at CROs
• Perform other responsibilities as assigned

What minimum qualifications do we require?

• PhD in the biological sciences plus 1+ years of relevant postdoctoral or biopharmaceutical experience/ MS degree plus 5+ years relevant biopharmaceutical experience

What additional qualifications will make you a stronger candidate?

• Hands-on experience designing and performing in vivo disease models in rodents, including tumor models or inflammatory disease models to assess efficacy and PK/PD is essential
• Hands-on experience with various routes of administration in rodents is essential
• Hands-on experience with rodent tissue collection and ex vivo processing techniques
• Strong oral and written communication skills, as well as excellent documentation and organizational skills are essential
• Strong interpersonal and communication skills, with a passion for participating in a fast-paced environment characterized by challenging and rigorous science, and creative thinking
• Experience with standard software analytical tools including Excel and GraphPad Prism
• Collaborative with effective listening skills and open, clear, consistent communication abilities
• Hands-on experience with murine tumor models and/or tumor xenograft models
• Experience working with small molecule therapies and characterizing PK/PD relationships
• Experience in management and oversight of external in vivo pharmacology studies at CROs
• Hands-on experience with multiparameter flow cytometry
• Ability to work effectively with project leads and project teams that have diverse personalities and styles
• Ability to work effectively with all collaborators in the drug discovery process: chemistry, DMPK, toxicology, bioinformatics, biology, clinical pharmacology, and translational medicine
• Commitment to Blueprint Medicines’ Core Values: Patients First, Thoughtfulness, Urgency, Trust, Optimism

Why Blueprint?

At Blueprint Medicines, we achieve impactful results because of our global crew of compassionate innovators – the Blue Crew. Through authentic relationships and our collective entrepreneurial spirit and action, we are each empowered to take ownership and execute with strategic prioritization. We put trust in our people to break through norms and conventions using their individual strengths and insights, which drives our success.

This is the place where the extraordinary becomes reality, and you could be part of it. Patients are waiting. Are you ready to make the leap?

COVID-19 Vaccination Requirement

As a biotechnology organization, it is our responsibility to do everything we can to safeguard the health and safety of our workforce, our communities, and the patients we serve. That is why, prior to their start date, new hires must provide confirmation that they are fully vaccinated against COVID-19, or be approved by Blueprint for an exemption for health reasons contraindicating the vaccines or sincerely held religious beliefs. Accommodation requests for either of these reasons should be made to TotalRewards@blueprintmedicines.com.

Equity, Diversity, Inclusion and Affirmative Action

At Blueprint Medicines, we foster a culture of equity, diversity and inclusion. A proud Equal Employment Opportunity and Affirmative Action employer, we consider all qualified applicants without regard to race, color, sex, gender identity or expression, sexual orientation, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, or any other characteristic protected under applicable law. We are also an E-Verify Employer. We will make reasonable accommodations, absent undue hardship, for qualified individuals with known disabilities. If you are an individual with a disability in need of an accommodation with the application or recruiting process, please reach out to TotalRewards@blueprintmedicines.com.

For more information, please see our EEO-AA Policy Statement , the EEO Poster and its Supplement , as well as our Pay Transparency Statement .

Blueprint Medicines is a global precision therapy company that invents life-changing therapies for people with cancer and blood disorders. Applying an approach that is both precise and agile, we create medicines that selectively target genetic drivers, with the goal of staying one step ahead across stages of disease. Since 2011, we have leveraged our research platform, including expertise in molecular targeting and world-class drug design capabilities, to rapidly and reproducibly translate science into a broad pipeline of precision therapies. Today, we are delivering approved medicines directly to patients in the United States and Europe, and we are globally advancing multiple programs for systemic mastocytosis, lung cancer and other genomically defined cancers, and cancer immunotherapy.

As a newly created role reporting to the VP of Global Patient Affairs, the Director of International Patient Advocacy will be responsible for leading and developing our patient advocacy vision and strategy in Europe and other key regions outside of the U.S.A. This position is critical in building, cultivating, and advancing strategic partnerships with international and national patient advocacy groups and other relevant stakeholders with the intent to address patient needs aligned with Blueprint’s global patient advocacy priorities and related business goals. This is a highly cross-functional and engaged role working with internal and external stakeholders and leaders. The candidate will be responsible for driving strategy across specific global markets, focused on addressing issues and developing solutions aligned with Blueprint’s patient-focused aspiration and our market opportunities.

What will you do?

• Shape and champion patient advocacy vision as a member of the global patient advocacy team
• Elevate and advance Blueprint’s patient advocacy strategy in Europe and other regions of the world
• Inform and advance European and international strategy to bring innovative medicines to patients by collaborating closely with the Medical Affairs team and other cross functional partners within the international organization
• Serve as the primary point of contact for patient organizations to build and maintain sustainable, actionable, and trusting engagement and relationships
• Develop international patient advocacy engagement strategy that propel partnerships to advance shared interests between Blueprint and the patient advocacy community
• Develop and implement initiatives that engage patient groups, consortia, health systems, to support patient needs, engagement, capacity building in advocacy, and advance healthcare policies that benefit patient care and outcomes
• Build and maintain strong relationships especially with relevant European patient advocacy organizations, leveraging expertise to strengthen the value proposition regarding the overall patient experience
• Engage with professional societies and industry organizations focused on advancing clinical knowledge, infrastructure, and practice enabling of the adoption of precision medicines to improve patient outcomes
• Work to infuse the patient perspective and strategic insights from patient advocacy group partners into the business, leveraging existing initiatives and new opportunities to inform and shape strategy from discovery to clinical development to commercialization
• Be a leader of the company’s patient-centric culture, driven by our “patients first” core value, by creating innovative and impactful opportunities to connect employees to the patient experience and human impact of our efforts and foster a collective sense of purpose, accomplishment, and joy
• Be a thought leader in the field of patient advocacy and contribute to efforts to advance corporate visibility and reputation through speaking and authorship opportunities
• Must be willing and able to travel (approximately 40%) and regularly meet with patient advocacy organizations and other relevant stakeholders across diverse geographies

What minimum qualifications do we require?

• Bachelor’s degree required; advanced degree preferred (e.g. MS, PhD, or MD)
• Minimum 7 years of direct patient advocacy experience in the biopharmaceutical industry; overall 15 years of relevant industry or non-profit experience

What additional qualifications will make you a stronger candidate?

• Experience in rare diseases and/or hematology/oncology
• Strong understanding of patient care models, drug development and regulatory processes, and commercialization of therapeutics including market access processes in Europe
• Proficient in English at a professional level, both written and spoken.
• A proven track record in cultivating, building, and managing multiple long-term, collaborative relationships with patient advocacy organizations
• Experience working in an associated field, such as Communications, Government Affairs or Policy work
• A deep understanding of how to identify and address the emotional, physical, and cultural barriers patients experience
• Excellent relationship building, stakeholder management, communication and interpersonal skills
• Ability to work with multidisciplinary teams
• Flexible, with positive attitude, strong ability to multitask, prioritize projects effectively and communicate at all levels within the company
• Demonstrated success in building relationships with patient groups in support of drug development and product launches in the rare disease space
• Demonstrated ability translating complex topics into compelling communications for various audiences
• Excellent writer, editor and storyteller; proven ability crafting various kinds of patient facing materials (e.g. posters, presentations, videos, social media efforts, campaigns)
• Ability to serve as a company ambassador with external stakeholders, align internal stakeholders and achieve results through collaboration
• Commitment to our Core Values: Patients First, Thoughtfulness, Urgency, Trust, Optimism

Why Blueprint?

At Blueprint Medicines, we achieve impactful results because of our global crew of compassionate innovators – the Blue Crew. Through authentic relationships and our collective entrepreneurial spirit and action, we are each empowered to take ownership and execute with strategic prioritization. We put trust in our people to break through norms and conventions using their individual strengths and insights, which drives our success.

This is the place where the extraordinary becomes reality, and you could be part of it. Patients are waiting. Are you ready to make the leap?

Blueprint Medicines is a global precision therapy company that invents life-changing therapies for people with cancer and blood disorders. Applying an approach that is both precise and agile, we create medicines that selectively target genetic drivers, with the goal of staying one step ahead across stages of disease. Since 2011, we have leveraged our research platform, including expertise in molecular targeting and world-class drug design capabilities, to rapidly and reproducibly translate science into a broad pipeline of precision therapies. Today, we are delivering approved medicines directly to patients in the United States and Europe, and we are globally advancing multiple programs for systemic mastocytosis, lung cancer and other genomically defined cancers, and cancer immunotherapy.

The Medical Affairs Director France/Belux is a leadership role defining and executing the medical strategy and managing the field-based Precision Medicines Liaisons (PML) team in alignment with local, international, and global plans. This role to foster top class dynamic and nimble field teams that allow for local decision making, autonomy and flexibility while maintaining the PMLs as the vital link for effective Medical Affairs activities in the field. The Medical Director will manage the business practices, policies, and general operations, is a member of the Country Leadership Team as well as of the International Medical Affairs Leadership Team. This role is reporting to the VP Medical Affairs International with a dotted line to the VP & General Manager North Region.

What will you do?

• Act as scientific leader, responsible for the generation and communication of scientific data and ensuring that all Medical Affairs activities are conducted with utmost integrity and compliance.
• Set the country strategies by contributing to the alignment of medical strategies with commercial and market access plans.
• Support resource and budget planning and management to ensure the medical needs and opportunities are met.
• Actively supports the France/Belux region commercial organization to promote the scientific and medical value of Blueprint’s products.
• Actively supports the France/Belux region Market Access team for HTA submission (HAS CT dossier), Early Access Request submission dossiers, and related engagements to support the clinical value assessment of BPM medicines
• Develop the Country Medical plan and implement local medical initiatives (including real-world evidence generation strategies) to foster disease awareness, fulfil unmet patient need and build on external scientific interest (e.g. compassionate use programs or investigator-initiated trials).
• Lead and manage a team of PMLs, +/- Medical Advisor and ensure development of team members from a scientific and career point of view.
• Provides input into development of local marketing material and is accountable for medical approval of all marketing and sales strategies and programs to ensure the highest degree of medical and ethical standards, in compliance with corporate standards and government/industry regulations.
• Works closely with local, regional, and global market access colleagues on price and reimbursement dossiers.
• Alignment with the Global and International team on plans and processes.
• Guarantees conduct of medical and scientific activities according to all relevant regulations and Blueprint SOPs and by closely liaising with the global and international regulatory affairs teams.
• Drives engagement of HCPs, professional societies and other key customers, including patients advocacy groups.
• Fosters the establishment and maintenance of local scientific advisory boards, round tables, expert meetings and promotes and assists in advocacy development.
• Closely liaises with global teams to review and supervise local clinical programs. Support investigator/selection management. Ensures a strategic approach to such programs, and the development of clinical data to support the appropriate use of the Company's products.

What minimum qualifications do we require?

• Advanced doctoral degree required: Medical Doctor, PhD or PharmD

What additional qualifications will make you a stronger candidate?

• MD, PharmD or PhD, with Oncology a/o Rare Disease experience is preferred.
• Minimum 8 years in Medical Affairs positions.
• Experience with product launches.
• Understanding of pharmaceutical commercial, access, medical and scientific needs on a local, regional and global basis.
• Medical and scientific excellence with demonstrated ability to perform in a leadership role that requires interacting with cross-functional, global team.
• Knowledge of local country regulations, guidelines, codes of practices and Access realities
• Operational excellence: management skills, planning, prioritization, decision making, objective setting and plan execution.
• Solid peer relationships with exposure to scientific and clinical experts, with a demonstrated ability to engage internal and external leaders.
• Excellent written and oral communication skills in French and English, including strong formal presentation skills in both languages.
• Track record of success in building and leading high-performance teams, and strong managerial experience essential. Previous experience leading MSL teams is an advantage. Able to attract, develop, inspire, and retain key talent.
• Comprehension of respective country health care system guidelines, healthcare privacy laws and any other regulatory guidelines.
• Nimble and energetic in a fast-paced, dynamic, and collaborative environment. Capable of taking a hands-on approach and willing to “roll up sleeves”.
• Extensive travel is required as part of this position (40%).
• Leadership style that fits our culture, highest integrity and ethical behavior, respect for people, a passion for science and a desire to make a difference.
• Work collaboratively, use resources carefully and build a great place to work and grow.
• Commitment to our Core Values: Patients First, Thoughtfulness, Urgency, Trust, Optimism

Why Blueprint?

At Blueprint Medicines, we achieve impactful results because of our global crew of compassionate innovators – the Blue Crew. Through authentic relationships and our collective entrepreneurial spirit and action, we are each empowered to take ownership and execute with strategic prioritization. We put trust in our people to break through norms and conventions using their individual strengths and insights, which drives our success.

This is the place where the extraordinary becomes reality, and you could be part of it. Patients are waiting. Are you ready to make the leap?

Blueprint Medicines is a global precision therapy company that invents life-changing therapies for people with cancer and blood disorders. Applying an approach that is both precise and agile, we create medicines that selectively target genetic drivers, with the goal of staying one step ahead across stages of disease. Since 2011, we have leveraged our research platform, including expertise in molecular targeting and world-class drug design capabilities, to rapidly and reproducibly translate science into a broad pipeline of precision therapies. Today, we are delivering approved medicines directly to patients in the United States and Europe, and we are globally advancing multiple programs for systemic mastocytosis, lung cancer and other genomically defined cancers, and cancer immunotherapy.

The Regional Business Director will be responsible for maximizing revenue by driving sales performance and providing leadership to the Area Business Managers within a given region. Oversee the implementation and execution of sales / marketing disease, diagnostic and branded educational awareness. Maintain effective communication and relationships with key customers and internal stakeholders. This individual will report to the National Business Director, East.

What will you do?

• Hiring, training, retention, and professional development of Area Business Managers across the region.
• Drive strong sales performance with your ABMs to ensure sales forecasts and KPI’s are met or exceeded.
• Conducts a required number of monthly field visits to effectively coach the use of approved resources and drive therapeutic and territory expectations.
• Ensures a high level of clinical acumen, working with ABMs on customer messaging during HCP interactions to deliver compliant impactful conversations.
• Maintain understanding of current market dynamics, institutional and community accounts, key influencers and opinion leaders. Routinely share information with all Blueprint Medicines stakeholders.
• Provides input into resource allocation decisions across the region. Effective management of annual budgeting for sales activity and delivery of expenditure within agreed upon timelines.
• Communicate incentive plans for the team and monitor monthly performance targets.
• Work with relevant internal teams to ensure alignment of account/ HCP activities across all business functions.
• Perform quarterly business reviews and provide leadership and strategic direction to Area Business Managers to achieve performance objectives
• Regular utilization of a variety of analytical tools to understand and evaluate the business or order to best determine how to coach ABMs to accomplish sales objectives and effectively deploy resources.
• Work with ABMs to develop local market business plans that ensure achievement of goals and objectives. Ensures appropriate planning to drive effective implementation of strategic plan.
• Acts with integrity and is a role model to the team. Sets clear expectations regarding ethical behavior and strict adherence to compliance standards. Apply appropriate performance management and accountability measures.
• Creates, builds, and maintains relationships and regular communication with physicians and key thought leaders.
• Develops, leads and facilitates team POA meetings.

What minimum qualifications do we require?

• Bachelor’s Degree
• 5-7+ years of pharmaceutical experience in oncology and/or rare disease
• 5+ years of managing people OR 2+ years serving in BPMC commercial role
• Ability to travel within the US on a regular basis which may include overnight and weekend travel

What additional qualifications will make you a stronger candidate?

• Experience selling and/or leading teams in complex environments; companion diagnostics, specialty pharmacy / patient HUB
• Experience supporting oral oncolytics and/or diagnostics highly preferred
• Demonstrated success with building and/or leading high performing field teams in a true “start-up” environment highly preferred
• Demonstrated success within niche markets
• Proven track record of employee development and performance management
• Demonstrated success across multiple drug launches in applicable specialty markets
• Excellent leadership coaching and performance management abilities
• Flexibility to adapt to a rapidly changing environment
• Robust analytical and problem-solving skills
• Ability to build/develop a market where the patient journey touches multiple HCP stakeholders
• Excellent interpersonal skills, with a proven ability to collaborate with ross functional partners and seek creative solutions to barriers
• Skilled in identifying opportunities and threats to the business, while operating with a high sense of urgency
• Commitment to Blueprint Medicines’ Core Values: Patients First, Thoughtfulness, Urgency, Trust, Optimism

Why Blueprint?

At Blueprint Medicines, we achieve impactful results because of our global crew of compassionate innovators – the Blue Crew. Through authentic relationships and our collective entrepreneurial spirit and action, we are each empowered to take ownership and execute with strategic prioritization. We put trust in our people to break through norms and conventions using their individual strengths and insights, which drives our success.

This is the place where the extraordinary becomes reality, and you could be part of it. Patients are waiting. Are you ready to make the leap?

COVID-19 Vaccination Requirement

As a biotechnology organization, it is our responsibility to do everything we can to safeguard the health and safety of our workforce, our communities, and the patients we serve. That is why, prior to their start date, new hires must provide confirmation that they are fully vaccinated against COVID-19, or be approved by Blueprint for an exemption for health reasons contraindicating the vaccines or sincerely held religious beliefs. Accommodation requests for either of these reasons should be made to TotalRewards@blueprintmedicines.com.

Equity, Diversity, Inclusion and Affirmative Action

At Blueprint Medicines, we foster a culture of equity, diversity and inclusion. A proud Equal Employment Opportunity and Affirmative Action employer, we consider all qualified applicants without regard to race, color, sex, gender identity or expression, sexual orientation, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, or any other characteristic protected under applicable law. We are also an E-Verify Employer. We will make reasonable accommodations, absent undue hardship, for qualified individuals with known disabilities. If you are an individual with a disability in need of an accommodation with the application or recruiting process, please reach out to TotalRewards@blueprintmedicines.com.

For more information, please see our EEO-AA Policy Statement , the EEO Know Your Rights Poster , as well as our Pay Transparency Statement .

Blueprint Medicines is a global precision therapy company that invents life-changing therapies for people with cancer and blood disorders. Applying an approach that is both precise and agile, we create medicines that selectively target genetic drivers, with the goal of staying one step ahead across stages of disease. Since 2011, we have leveraged our research platform, including expertise in molecular targeting and world-class drug design capabilities, to rapidly and reproducibly translate science into a broad pipeline of precision therapies. Today, we are delivering approved medicines directly to patients in the United States and Europe, and we are globally advancing multiple programs for systemic mastocytosis, lung cancer and other genomically defined cancers, and cancer immunotherapy.

You will be responsible for developing global regulatory strategies to advance Blueprint’s portfolio. This position will lead and contribute to activities in support of high-quality CMC sections of regulatory documentation.

What will you do?

• Work with internal partners to develop regulatory CMC strategies, identify potential regulatory risks, and develop contingency plans for projects in various phases of development.
• Manage and lead assigned projects, including timelines and submission planning.
• Plan and prepare CMC documentation for Clinical Trial Applications, IND submissions and amendments, marketing applications, supplements, variations and other communications with regulatory authorities
• Ensure the timely completion of regulatory filings such as CTA, IMPD, IND and associated amendments.
• Evaluate CMC change controls and provide regulatory input pertaining to all facets of manufacturing changes.
• Exercise good judgment in elevating and communicating actual or potential issues.
• Provide feedback and mentorship in accordance with phase-appropriate regulatory expectations to ensure the quality and safety of clinical product.
• Resolve complex and ambiguous situations, with ability to understand the scientific principles as it relates to regulatory requirements and strategy.
• Capable of critical thinking and proposing innovative solutions to regulatory problems
• Comfortable in a dynamic, highly accountable environment where you can make a clear impact
• Be a standout colleague, who listens effectively and invites response and discussion
• Act as a collaborator who communicates in an open, clear, complete, timely and consistent manner

What minimum qualifications do we require?

• Bachelor’s degree in a scientific/engineering field (advanced degree preferred).
• At least 5 years of pharmaceutical industry experience and solid understanding of drug development process.
• Must have experience in pharmaceutical development (e.g. analytical, process, formulations, quality).
• At least 3 years of regulatory CMC experience with US product development including CMC life cycle management.

What additional qualifications will make you a stronger candidate?

• Experience with Global post-approval regulations/guidance, strategies and submissions.
• Proficient in Microsoft WORD, Project, PowerPoint, and Adobe Acrobat.
• Ability to set and drive aggressive project timelines
• Commitment to our Core Values: Patients First, Thoughtfulness, Urgency, Trust, Optimism

Why Blueprint?

At Blueprint Medicines, we achieve impactful results because of our global crew of compassionate innovators – the Blue Crew. Through authentic relationships and our collective entrepreneurial spirit and action, we are each empowered to take ownership and execute with strategic prioritization. We put trust in our people to break through norms and conventions using their individual strengths and insights, which drives our success.

This is the place where the extraordinary becomes reality, and you could be part of it. Patients are waiting. Are you ready to make the leap?

COVID-19 Vaccination Requirement

As a biotechnology organization, it is our responsibility to do everything we can to safeguard the health and safety of our workforce, our communities, and the patients we serve. That is why, prior to their start date, new hires must provide confirmation that they are fully vaccinated against COVID-19, or be approved by Blueprint for an exemption for health reasons contraindicating the vaccines or sincerely held religious beliefs. Accommodation requests for either of these reasons should be made to TotalRewards@blueprintmedicines.com.

Equity, Diversity, Inclusion and Affirmative Action

At Blueprint Medicines, we foster a culture of equity, diversity and inclusion. A proud Equal Employment Opportunity and Affirmative Action employer, we consider all qualified applicants without regard to race, color, sex, gender identity or expression, sexual orientation, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, or any other characteristic protected under applicable law. We are also an E-Verify Employer. We will make reasonable accommodations, absent undue hardship, for qualified individuals with known disabilities. If you are an individual with a disability in need of an accommodation with the application or recruiting process, please reach out to TotalRewards@blueprintmedicines.com.

For more information, please see our EEO-AA Policy Statement , the EEO Poster and its Supplement , as well as our Pay Transparency Statement .

Blueprint Medicines is a global precision therapy company that invents life-changing therapies for people with cancer and blood disorders. Applying an approach that is both precise and agile, we create medicines that selectively target genetic drivers, with the goal of staying one step ahead across stages of disease. Since 2011, we have leveraged our research platform, including expertise in molecular targeting and world-class drug design capabilities, to rapidly and reproducibly translate science into a broad pipeline of precision therapies. Today, we are delivering approved medicines directly to patients in the United States and Europe, and we are globally advancing multiple programs for systemic mastocytosis, lung cancer and other genomically defined cancers, and cancer immunotherapy. 

To aid in this mission, the Translational Medicine (TM) team at Blueprint is seeking a highly motivated, scientifically creative, and collaborative Senior Scientist to work in a fast-paced environment within a cross-functional team. You will be a highly motivated scientist, dedicated to biomarker discovery, clinical biomarker development, implementation, and interpretation to help advance our oncology pipeline. You will be responsible for developing and executing integrated biomarker strategies utilizing state-of-the-art technologies. A strong understanding of tumor biology, molecular pathways, and the ability to analyze and interpret complex data sets will be key strengths. You will have the opportunity to contribute scientifically across the portfolio to programs at various discovery and development stages, ranging from discovery to clinical.

What will you do?

• Define and execute translational and biomarker strategies for Blueprint’s clinical-stage oncology programs with a focus on mechanism of action, target engagement, establishment of PK/PD/efficacy relationships, patient selection strategies and understanding mechanisms of intrinsic and acquired resistance.
• Ensure that discovery, pre-clinical, and clinical biomarker plans are developed and implemented efficiently and aligned with the strategic needs of the program.
• Perform and/or oversee experimental design, lab-based research, data analysis, data integration, and data storage.
• Independently conduct, optimize, and proactively troubleshoot assays (whether in-house or CRO).
• Manage external biomarker analysis at specialty CROs including experimental design, validation, qualification, budgeting, timelines, and oversight of quality and execution during trial conduct.
• Represent Translational Medicine within project/program teams; share scientific and strategic perspectives, generate data to support team needs, meet project/program milestones for TM responsibilities.
• Contribute to the development of clinical protocols, laboratory manuals, regulatory submissions, abstracts, and publications.
• Analyze, interpret, and present integrated scientific results and implications for program strategy to internal and external stakeholders.
• Effectively collaborate across internal functions including discovery, translational, clinical pharmacology, clinical development, data management and regulatory affairs to ensure successful execution in the clinic.
• Clearly communicate translational strategies, timelines, dependencies, risks, and mitigations to team members.
• Evaluate new technologies and partner with external collaborators to enable exploratory biomarkers
• Regularly present research to Translational Medicine and integrated project teams highlighting implications and opportunities for broader program.

What minimum qualifications do we require?

• PhD in oncology, molecular biology, cell biology, or related discipline
• Relevant post-doctoral training and/or 4/6+ years of relevant experience in a biopharmaceutical research setting

What additional qualifications will make you a stronger candidate?

• Demonstrated knowledge of clinically relevant biomarker approaches across a range of technology platforms
• Experience working with central laboratories and contract research organizations supporting specialized biomarker analysis
• Familiarity with working in the GxP environment with a focus on quality
• Strong interpersonal and communication skills, with a passion for participating in a fast-paced environment characterized by challenging and rigorous science, and innovative thinking
• Strong oral and written communication skills, as well as excellent documentation and organizational skills are essential
• Familiarity with Companion Diagnostics and personalized medicine development is strongly preferred.
• Hands-on experience with translational assays and data is preferred.
• Extensive experience with state-of-the-art assays, and standard software analytical tools, xlsx, Prism, etc.
• Familiarity with PK/PD/efficacy relationships and delivering PD readouts by western and plate-based assays for in vivo tumor models is preferred
• A great teammate, who listens effectively and invites response and discussion
• A collaborator who communicates in an open, clear, complete, timely and consistent manner
• At home in a highly accountable environment where you can make a clear impact
• Commitment to Blueprint Medicines’ Core Values: Patients First, Thoughtfulness, Urgency, Trust, Optimism

Why Blueprint?

At Blueprint Medicines, we achieve impactful results because of our global crew of compassionate innovators – the Blue Crew. Through authentic relationships and our collective entrepreneurial spirit and action, we are each empowered to take ownership and execute with strategic prioritization. We put trust in our people to break through norms and conventions using their individual strengths and insights, which drives our success.

This is the place where the extraordinary becomes reality, and you could be part of it. Patients are waiting. Are you ready to make the leap?

COVID-19 Vaccination Requirement

As a biotechnology organization, it is our responsibility to do everything we can to safeguard the health and safety of our workforce, our communities, and the patients we serve. That is why, prior to their start date, new hires must provide confirmation that they are fully vaccinated against COVID-19, or be approved by Blueprint for an exemption for health reasons contraindicating the vaccines or sincerely held religious beliefs. Accommodation requests for either of these reasons should be made to TotalRewards@blueprintmedicines.com.

Equity, Diversity, Inclusion and Affirmative Action

At Blueprint Medicines, we foster a culture of equity, diversity and inclusion. A proud Equal Employment Opportunity and Affirmative Action employer, we consider all qualified applicants without regard to race, color, sex, gender identity or expression, sexual orientation, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, or any other characteristic protected under applicable law. We are also an E-Verify Employer. We will make reasonable accommodations, absent undue hardship, for qualified individuals with known disabilities. If you are an individual with a disability in need of an accommodation with the application or recruiting process, please reach out to TotalRewards@blueprintmedicines.com.

For more information, please see our EEO-AA Policy Statement , the EEO Poster and its Supplement , as well as our Pay Transparency Statement .

Blueprint Medicines is a global precision therapy company that invents life-changing therapies for people with cancer and blood disorders. Applying an approach that is both precise and agile, we create medicines that selectively target genetic drivers, with the goal of staying one step ahead across stages of disease. Since 2011, we have leveraged our research platform, including expertise in molecular targeting and world-class drug design capabilities, to rapidly and reproducibly translate science into a broad pipeline of precision therapies. Today, we are delivering approved medicines directly to patients in the United States and Europe, and we are globally advancing multiple programs for systemic mastocytosis, lung cancer and other genomically defined cancers, and cancer immunotherapy. 

The Medical Science Liaison is a field-based scientific and clinical expert who strategically supports the medical objectives of Blueprint Medicines’ development programs. The MSL is responsible for identifying, developing, and managing peer-to-peer relationships with a variety of healthcare providers, including oncologists, pathologists, and allergists/immunologists, as well as basic scientists in academic and community practices.

The MSL will be accountable to engage in high quality scientific exchange about the science and clinical application of our precision medicine portfolio to variety of external stakeholders, as well as obtain important insights about current practice, treatment landscapes, and emerging clinical and scientific data. In addition, MSLs are expected to build strong cross-functional relationships, as well as provide meaningful subject-matter expertise, to colleagues in Medical Affairs, Clinical Research, R&D, Patient Advocacy and Commercial, while maintaining full compliance with all relevant company, industry, legal, and regulatory requirements. They will report to the Regional Director of MSLs.

What will you do?

• Identify key opinion leaders and cultivate a network of experts for Blueprint Medicines disease areas of focus
• Respond to unsolicited requests and engage in meaningful, peer-to-peer scientific exchange of complex medical and scientific information with the oncology, pathology, and rare disease community
• Provide internal stakeholders with feedback and insights from interactions and discussions with HCPs.
• Deliver medical/scientific presentations to internal & external stakeholders
• Assist with company-sponsored clinical trials and facilitation of investigator-initiated trials (ISTs)
• Lead planning and execution of regional advisory boards
• Collaborate with cross functional partners on internal projects and external initiatives
• Provide educational meeting support at scientific congresses
• Support training of cross functional teams
• Adhere to corporate and healthcare compliance guidance in all activities, including those related to clinical trials, scientific interactions with internal and external groups, and responses to unsolicited requests for medical/scientific information
• Foster and maintain Blueprint’s positive and innovative culture with a newly formed field team

What minimum qualifications do we require?

• Advanced Clinical/Science degree or professional credentials required (MD/DO, PhD, PharmD, NP, PA)
• 3+ years of experience in the biotech or pharmaceutical industry in Medical Affairs, with experience working with cross-functional in-house and field-based teams
• Extensive travel is required as part of this position (60%)

What additional qualifications will make you a stronger candidate?

• Ensure compliance with corporate rules and government regulations
• Strong analytical skills, especially with regard to understanding and interpreting scientific and clinical research and literature, are essential
• Oncology or Rare Disease experience strongly preferred
• Strong interpersonal, presentation and communication skills and demonstrated ability to work collaboratively in a dynamic, team-oriented environment
• Creative problem-solving skills
• Demonstrated self-starter and team player with strong interpersonal skills
• Adept, nimble, energetic, and comfortable in a fast-paced, dynamic, and collaborative environment
• Capable of taking a hands-on approach and willing to “roll up one’s sleeves.”
• Commitment to Blueprint Medicines’ Core Values: Patients First, Thoughtfulness, Urgency, Trust, Optimism

Why Blueprint?

At Blueprint Medicines, we achieve impactful results because of our global crew of compassionate innovators – the Blue Crew. Through authentic relationships and our collective entrepreneurial spirit and action, we are each empowered to take ownership and execute with strategic prioritization. We put trust in our people to break through norms and conventions using their individual strengths and insights, which drives our success.

This is the place where the extraordinary becomes reality, and you could be part of it. Patients are waiting. Are you ready to make the leap?

COVID-19 Vaccination Requirement

As a biotechnology organization, it is our responsibility to do everything we can to safeguard the health and safety of our workforce, our communities, and the patients we serve. That is why, prior to their start date, new hires must provide confirmation that they are fully vaccinated against COVID-19, or be approved by Blueprint for an exemption for health reasons contraindicating the vaccines or sincerely held religious beliefs. Accommodation requests for either of these reasons should be made to TotalRewards@blueprintmedicines.com.

Equity, Diversity, Inclusion and Affirmative Action

At Blueprint Medicines, we foster a culture of equity, diversity and inclusion. A proud Equal Employment Opportunity and Affirmative Action employer, we consider all qualified applicants without regard to race, color, sex, gender identity or expression, sexual orientation, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, or any other characteristic protected under applicable law. We are also an E-Verify Employer. We will make reasonable accommodations, absent undue hardship, for qualified individuals with known disabilities. If you are an individual with a disability in need of an accommodation with the application or recruiting process, please reach out to TotalRewards@blueprintmedicines.com.

For more information, please see our EEO-AA Policy Statement , the EEO Know Your Rights Poster , as well as our Pay Transparency Statement .

Blueprint Medicines is a global precision therapy company that invents life-changing therapies for people with cancer and blood disorders. Applying an approach that is both precise and agile, we create medicines that selectively target genetic drivers, with the goal of staying one step ahead across stages of disease. Since 2011, we have leveraged our research platform, including expertise in molecular targeting and world-class drug design capabilities, to rapidly and reproducibly translate science into a broad pipeline of precision therapies. Today, we are delivering approved medicines directly to patients in the United States and Europe, and we are globally advancing multiple programs for systemic mastocytosis, lung cancer and other genomically defined cancers, and cancer immunotherapy. 

Blueprint Medicines is a global precision therapy company that invents life-changing therapies for people with cancer and hematologic disorders. Applying an approach that is both precise and agile, we create medicines that selectively target genetic drivers, with the goal of staying one step ahead across stages of disease. Since 2011, we have leveraged our research platform, including expertise in molecular targeting and world-class drug design capabilities, to rapidly and reproducibly translate science into a broad pipeline of precision therapies. Today, we are delivering approved medicines directly to patients in the United States and Europe, and we are globally advancing multiple programs for genomically defined cancers, systemic mastocytosis, and cancer immunotherapy.

The Precision Medicine Liaison is a field-based scientific and clinical expert who strategically supports the medical objectives of Blueprint Medicines’ development programs. The PML is responsible for identifying, developing, and managing peer-to-peer relationships with a variety of healthcare providers, including hematologists, oncologists, pathologists, dermatologists, gastroenterologists, and allergists/immunologists, as well as basic scientists, in academic and community practices.

The PML will be accountable to engage in high quality scientific exchange about the science and clinical application of our precision medicine portfolio to variety of external stakeholders, as well as obtain important insights about current practice, treatment landscapes, and emerging clinical and scientific data. In addition, the PML is expected to build strong cross-functional relationships, as well as provide meaningful subject-matter expertise, to colleagues in Medical Affairs, Clinical Research, R&D, Patient Advocacy and Commercial, while maintaining full compliance with all relevant company, industry, legal, and regulatory requirements. This position reports to the Country Medical Director and will cover the territory Central-South Italy.

What will you do?

• Identify key opinion leaders and cultivate a network of experts for disease areas of focus
• Respond to unsolicited requests and engage in meaningful, peer-to-peer scientific exchange of complex medical and scientific information with the oncology, hematology, pathology, and rare disease community
• Provide internal stakeholders with feedback and insights from interactions and discussions with HCPs.
• Accurately profile country and define local dynamics related to patient diagnosis and referral for treatment
• Deliver medical/scientific presentations to internal & external stakeholders
• Assist with company-sponsored clinical trials and facilitation of investigator-initiated trials (ISTs)
• Lead planning and execution of regional advisory boards
• Collaborate with cross functional partners on internal projects and external initiatives
• Provide educational meeting support at scientific congresses
• Support training of cross functional teams
• Adhere to corporate and healthcare compliance guidance in all activities, including those related to clinical trials, scientific interactions with internal and external groups, and responses to unsolicited requests for medical/scientific information
• Foster and maintain Blueprint’s positive and innovative culture
• Significant travel is required as part of this position

What minimum qualifications do we require?

• Advanced Clinical/Science degree or professional credentials required (MD/DO, PhD, PharmD, MSc)
• 3+ years of experience in the biotech or pharmaceutical industry in Medical Affairs

What additional qualifications will make you a stronger candidate?

• Experience working with cross-functional in-house and field-based teams
• Fluent written and spoken communication skills in English and in local language of geographic location where the position is based
• Rare Disease and/or oncology/hematology experience strongly preferred; combined is ideal
• Strong interpersonal, presentation and communication skills and demonstrated ability to work collaboratively in a dynamic, team-oriented environment
• Creative problem-solving skills
• Positive, solutions-oriented mindset
• Demonstrated self-starter and team player with strong interpersonal skills
• Adept, nimble, energetic, and comfortable in a fast-paced, dynamic, and collaborative environment
• Capable of taking a hands-on approach and willing to “roll up one’s sleeves.”
• Ensure compliance with corporate rules and local regulations
• Strong analytical skills, especially with regard to understanding and interpreting scientific and clinical research and literature, are essential
• Commitment to our Core Values: Patients First, Thoughtfulness, Urgency, Trust, Optimism

Why Blueprint?

At Blueprint Medicines, we achieve impactful results because of our global crew of compassionate innovators – the Blue Crew. Through authentic relationships and our collective entrepreneurial spirit and action, we are each empowered to take ownership and execute with strategic prioritization. We put trust in our people to break through norms and conventions using their individual strengths and insights, which drives our success.

This is the place where the extraordinary becomes reality, and you could be part of it. Patients are waiting. Are you ready to make the leap?

Blueprint Medicines is a global precision therapy company that invents life-changing therapies for people with cancer and blood disorders. Applying an approach that is both precise and agile, we create medicines that selectively target genetic drivers, with the goal of staying one step ahead across stages of disease. Since 2011, we have leveraged our research platform, including expertise in molecular targeting and world-class drug design capabilities, to rapidly and reproducibly translate science into a broad pipeline of precision therapies. Today, we are delivering approved medicines directly to patients in the United States and Europe, and we are globally advancing multiple programs for systemic mastocytosis, lung cancer and other genomically defined cancers, and cancer immunotherapy.