Longevity Industry Jobs

The Director, TTR Global Marketing will play a critical part in driving the commercial success of our AMVUTTRA® (vutrisiran) global launches in ATTR amyloidosis.  This role will be primarily focused on our global brand strategy and initiatives in ATTR amyloidosis.  Key responsibilities include leading the development and execution of our competitive differentiation strategy.  Collaboration across functions and regions is critical to be successful in this role.

This role will report to the Vice President, TTR Global Marketing.

Key Responsibilities

• Drive the development of global brand differentiation strategy for ATTR amyloidosis
• Monitor and evaluate competitive strategies and conduct scenario planning exercises to inform our global brand strategy and execution
• Drive the development and execution of a global brand strategic framework, messaging and core materials
• Develop clear and actionable actions to address HCP and patient barriers/opportunities to treatment initiation
• Partner with regional marketing teams to optimize our global campaigns and messages, as well as ensure global brand consistency
• Partner with medical teams to ensure existing and emerging data gaps are proactively identified and addressed
• Develop and execute society engagement plans and corresponding tactics
• Partner with key internal stakeholders and regions (medical affairs, regional marketing, digital center of excellence, launch excellence, customer insights, training, market access, legal and regulatory) to ensure alignment across functions and flawless, compliant execution.
• Partner effectively and appropriately manage Agency of Record and/or other external partners
• Effective management of global marketing operational budget

Qualifications

• BS/BA degree with over 10 years of pharmaceuticals experience
• Global and local brand marketing experience
• Successful track record operating in highly competitive environments
• Strong external and internal customer focus in a multi-disciplinary and matrix context
• Demonstrable ability to work collaboratively in a dynamic and high-pressure environment
• Excellent written and oral communication, presentation and facilitation skills
• Strong analytical and problem-solving skills; ability to combine attention to detail with big picture perspective

About Alnylam

Alnylam Pharmaceuticals (Nasdaq: ALNY) has led the translation of RNA interference (RNAi) into a whole new class of innovative medicines with the potential to transform the lives of people afflicted with rare and more prevalent diseases. Based on Nobel Prize-winning science, RNAi therapeutics represent a powerful, clinically validated approach to treating diseases at their genetic source by “interfering” with mRNA that cause or contribute to disease. Since our founding in 2002, Alnylam has led the RNAi Revolution and continues to turn scientific possibility into reality. 

Our people-first culture is guided by our core values: fiercely innovative, open culture, purposeful urgency, passion for excellence, and commitment to people, and these values influence how we work and the business decisions we make. Thanks to feedback from our employees over the years, we’ve been fortunate to be named a top employer around the world. Alnylam is extremely proud to have been recognized as the #1 Large Employer by Boston Globe Top Places to Work in 2022, one of Science Magazine’s Top Biopharma Employers, one of America's Most Responsible Companies for 2023 by Newsweek, a Fast Company Best Workplace for Innovators, and a Great Place to Work in Canada, France, Italy, Spain, Switzerland, and UK – among others.

At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. We are dedicated to building an environment where employees can feel that they belong, can bring their authentic selves to work, and achieve to their full potential. By empowering employees to embrace their unique differences at work, our business grows stronger with advanced and original thinking, allowing us to bring groundbreaking medicines to patients.

Qualified applicants will receive consideration for employment without regard to their race, color, religion, age, sex, sexual orientation, gender identity or expression, national origin, ethnicity, marital status, protected veteran status, disability, or any other characteristics prohibited by law. Alnylam is an E-Verify employer.

The Associate Director, Medical Affairs Finance Business Partner (FBP) Lead is an exciting opportunity within the FBP team. In this role, you will be a trusted member of the Medical Affairs Leadership Team (MALT) providing critical financial insights, and support, to a dynamic organization within Alnylam. This role will collaborate closely with the Senior Vice President of Medical Affairs and other senior MALT leaders. The position will report into the Vice President of Finance, Commercial and Medical Affairs (MAC). 

The Associate Director will enjoy oversight of, and accountability for, the worldwide Medical Affairs Operating Expenses (OpEx). Partnering closely with FBP colleagues in the regions, this role not only reports on the overall financial position of the organization, but also controls the day to day financial management of the US and Global OpEx.  The successful candidate will coordinate all US-entity month end close processes including accrual calculation, headcount reconciliation and variance analysis. In addition, the Associate Director will lead the quarterly reforecast, the annual investment plan process, and long-range planning for the Medical Affairs organization. This position will lead a highly motivated Sr. Financial Analyst and will liaise will all functions within the wider finance organization (including the broader FBP team, Accounting, Procurement, Accounts Payable, etc).

Key Responsibilities

• Be a trusted advisor to the Sr. VP of Medical Affairs, collaborating closely with the Sr. Director of Medical Operations and the Medical Affairs HR Business partner, in order to provide financial decision support that helps the drive the business forward in a financially accountable way.
• Responsible for leading all business and financial planning processes related to the worldwide Medical Affairs organization, including monthly latest view, quarterly reforecast, annual investment planning, and long-range planning.
• Lead the completion of all month-end accrual accounting activities, expense budgets and expense forecasts for US & Global Medical Affairs departments.
• Participate in the end to end P2P process; approving requisitions, analyzing spend by vendor, and liaising with the business in order to accurately report accruals and expense.
• Analyze data to explain trends and variances from budget and forecast to upper management and perform ad-hoc analysis with the Global MAC and Corporate FP&A teams.
• Ensure alignment on forecast assumptions, and other critical analytical assessments, with business partners in order to prioritize investments across the Medical Affairs organization.
• Seek continuous improvements to FBP processes through process design, automation, improved communications, training and sharing of best practices.
• Ensure coherent financial analysis and alignment across MAC through the identification of opportunities to invest, reduce costs, and mitigate risks
• Develop strong relationships with other key members of Global Finance organizations.
• Complete special projects and ad hoc analyses as required by the VP of MAC Finance.

Qualifications

• Master’s in Finance or Accounting (or equivalent) from an accredited university required. MBA is desirable
• Minimum of 10+ years of finance or accounting experience required
• Life Sciences/Biotech/Pharmaceutical industry experience preferred
• Proficiency in Microsoft Office required, Microsoft Excel a must
• Experience with SAP and Adaptive preferred
• Ability to thrive in a dynamic and fast paced international environment - flexibility, team oriented, collaborative work style and a positive attitude
• Ability to lead and influence both cross-functional teams and direct reports
• Ability to complete tasks with a high degree of accuracy utilizing strong analytical and organizational skills
• Demonstrated excellent written and verbal communication
• Demonstrated attention to detail and presenting accurate information
• Strong sense of accountability and ownership
• Excellent interpersonal skills and ability to work effectively with multiple functions and teams

About Alnylam

Alnylam Pharmaceuticals (Nasdaq: ALNY) has led the translation of RNA interference (RNAi) into a whole new class of innovative medicines with the potential to transform the lives of people afflicted with rare and more prevalent diseases. Based on Nobel Prize-winning science, RNAi therapeutics represent a powerful, clinically validated approach to treating diseases at their genetic source by “interfering” with mRNA that cause or contribute to disease. Since our founding in 2002, Alnylam has led the RNAi Revolution and continues to turn scientific possibility into reality. 

Our people-first culture is guided by our core values: fiercely innovative, open culture, purposeful urgency, passion for excellence, and commitment to people, and these values influence how we work and the business decisions we make. Thanks to feedback from our employees over the years, we’ve been fortunate to be named a top employer around the world. Alnylam is extremely proud to have been recognized as the #1 Large Employer by Boston Globe Top Places to Work in 2022, one of Science Magazine’s Top Biopharma Employers, one of America's Most Responsible Companies for 2023 by Newsweek, a Fast Company Best Workplace for Innovators, and a Great Place to Work in Canada, France, Italy, Spain, Switzerland, and UK – among others.

At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. We are dedicated to building an environment where employees can feel that they belong, can bring their authentic selves to work, and achieve to their full potential. By empowering employees to embrace their unique differences at work, our business grows stronger with advanced and original thinking, allowing us to bring groundbreaking medicines to patients.

Qualified applicants will receive consideration for employment without regard to their race, color, religion, age, sex, sexual orientation, gender identity or expression, national origin, ethnicity, marital status, protected veteran status, disability, or any other characteristics prohibited by law. Alnylam is an E-Verify employer

We are looking for experienced Business Account Executives (BAEs) with rare disease experience to promote ONPATTRO® (patisiran) in the U.S. ONPATTRO was approved in August 2018 by the FDA for the treatment of the polyneuropathy of hereditary transthyretin-mediated amyloidosis (hATTR amyloidosis) in adults. The successful candidate will also have the opportunity to be part of the sales team responsible for the commercialization of Alnylam’s second therapeutic in Alnylam’s TTR portfolio, AMVUTTRA™ . hATTR patients often spend years undiagnosed and misdiagnosed. This is an amazing opportunity to educate and enhance the market’s knowledge of hATTR amyloidosis.

The BAE (TTR BAE) will be principally responsible for driving physician and patient identification, disease awareness, overall market development, and brand awareness within their ascribed territory. The BAE will be responsible for achieving territory targets and other business objectives through account and customer strategies, while also partnering & collaborating very closely with internal and external stakeholders to effectively manage all aspects of the regional business. The achievement of targets will be based in Alnylam values: our commitment to people, sense of urgency, passion for excellence, innovation & discovery, and open culture as well as our unwavering commitment to integrity.

The position reports into the (TTR) Regional Business Director.

Key Responsibilities

• Drives physician and patient identification, market development in polyneuropathy hATTR amyloidosis, and brand awareness by building and executing against a territory strategy and account specific plans.
• Continuously assesses sales opportunities within markets and accounts to maintain and grow their business.
• Effectively prioritizes and manages time, activities, and resources to optimize access to and development of accounts with the most sales potential.
• Builds and maintains relationships with physicians by maximizing their time through pre-call planning, leveraging insights to tailor a call plan, and conducting post-call analysis to continually refine and enhance their approach.
• Proactively builds effective working relationships with internal/external stakeholders; can drive agreement/decisions from multiple stakeholders; can read people’s emotions and flex communication style. Adjusts their approach based on different stakeholder needs, concerns, or audience member to drive alignment and meet their work goals.   
• Effectively communicates and closely collaborates with stakeholders across commercial, compliance, legal, market access, and patient care centers to help ensure access at site of care.
• Builds individual account plans for key accounts and physicians including how to approach those customers, achieve sales goals, and maximize sales results.
• Collaborates with key accounts and physicians to drive patient identification through market development and physician education; develop a territory strategy to retain customers.
• Executes programs, in-services, and in office presentations for their territory across multiple account types such as clinics and infusion centers.
• Routinely reports territory-level market dynamics and trends, including prescriber opinion and competitive activity, to manager and escalates to home office as needed.
• Demonstrates and upholds the highest standards of integrity and compliance.

Qualifications

• Bachelor’s required: MBA/Science Degree preferred.
• 7+ years of progressive and visibly successful business experience in biotech or specialty pharmaceutical industry. 
• 2 plus years of rare disease experience.  Deep experience in Cardiology and Neurology are important and strongly preferred.  Hematology knowledge and experience is a plus.
• Understanding and experience working with in-house patient support services required.
• A successful track record in pharmaceutical sales/management.
• Must be familiar with relevant legal and regulatory environment in biotech/pharmaceutical industry.
• Product launch experience is a plus including a working knowledge of government and commercial payers.
• Experience in driving, leading and delivering upon territory-level cross functional business planning and influencing without authority.
• Understanding of patient services and specialty channel distribution is preferred.
• Hospital / Institution knowledge and expertise with pharmacy formulary processes.
• Must be comfortable spending 60% of time traveling; some overnight travel required.
• Driving is an essential duty of the job; candidates must have a valid driver's license to be considered.
• Must live within assigned territory.
• Demonstrated commitment to ethics and integrity.

About Alnylam

Alnylam Pharmaceuticals (Nasdaq: ALNY) has led the translation of RNA interference (RNAi) into a whole new class of innovative medicines with the potential to transform the lives of people afflicted with rare and more prevalent diseases. Based on Nobel Prize-winning science, RNAi therapeutics represent a powerful, clinically validated approach to treating diseases at their genetic source by “interfering” with mRNA that cause or contribute to disease. Since our founding in 2002, Alnylam has led the RNAi Revolution and continues to turn scientific possibility into reality. 

Our people-first culture is guided by our core values: fiercely innovative, open culture, purposeful urgency, passion for excellence, and commitment to people, and these values influence how we work and the business decisions we make. Thanks to feedback from our employees over the years, we’ve been fortunate to be named a top employer around the world. Alnylam is extremely proud to have been recognized as the #1 Large Employer by Boston Globe Top Places to Work in 2022, one of Science Magazine’s Top Biopharma Employers, one of America's Most Responsible Companies for 2023 by Newsweek, a Fast Company Best Workplace for Innovators, and a Great Place to Work in Canada, France, Italy, Spain, Switzerland, and UK – among others. 

At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. We are dedicated to building an environment where employees can feel that they belong, can bring their authentic selves to work, and achieve to their full potential. By empowering employees to embrace their unique differences at work, our business grows stronger with advanced and original thinking, allowing us to bring groundbreaking medicines to patients. 

Qualified applicants will receive consideration for employment without regard to their race, color, religion, age, sex, sexual orientation, gender identity or expression, national origin, ethnicity, marital status, protected veteran status, disability, or any other characteristics prohibited by law. Alnylam is an E-Verify employer.

Manager Global Safety Systems (GSS) will support Argus Safety, OBIEE, Axway, and other technical solutions to assist Global Patient Safety and Risk Management (GPSRM). In addition, the role supports the configuration of studies, products, reporting rules, periodic reports, and other system configurations.

Key Responsibilities

Work with GPSRM staff to create solutions for extracting and analyzing safety data. Experience in BI Publisher, Argus Analytics (OBIEE) is preferred.

• Responsible for generating formal reports, summaries, and listings supporting medical monitoring, signal detection, and aggregate reporting deliverables (PBRER, DSUR) in conjunction with the database service provider.
• Work with GPSRM staff to complete the configuration forms and coordinate with the database service provider to complete the needed configurations.
• Serve as a system administrator and perform configurations/master data updates like code lists, user access, reporting rules, product, and study.
• Perform quality checks on configuration changes performed by the database service provider; Identify discrepancies between the request and the implementation and resolve or initiate their resolution.
• Assist in the process of qualification/validation of GSD applications.
• Willing to take on additional other departmental tasks, as assigned by your immediate supervisor, to ensure Alnylam’s compliance with all regulatory agency and ICH regulations and guidelines governing the reporting of adverse events and product complaints.

Qualifications

• BS Computer Science/equivalent qualification with at least four (4) years of experience.
• Experience supporting Oracle Argus Safety is required. Additionally, work experience with Oracle cloud is preferred.
• Experience in safety reporting applications is required. Knowledge of OBIEE is preferred.
• Relational database knowledge working with Oracle and SQL is required.
• General knowledge of Software Development Lifecycle (SDLC) is required, experience performing qualification/validation is required.
• General knowledge of Electronic Data Interchange (Axway B2Bi Interchange in particular a plus).
• General knowledge about the global safety reporting requirements and ICH E2B guidelines that govern the international reporting of adverse events on investigational and marketed products are preferred.

About Alnylam

Alnylam Pharmaceuticals (Nasdaq: ALNY) has led the translation of RNA interference (RNAi) into a whole new class of innovative medicines with the potential to transform the lives of people afflicted with rare and more prevalent diseases. Based on Nobel Prize-winning science, RNAi therapeutics represent a powerful, clinically validated approach to treating diseases at their genetic source by “interfering” with mRNA that cause or contribute to disease. Since our founding in 2002, Alnylam has led the RNAi Revolution and continues to turn scientific possibility into reality.

Our people-first culture is guided by our core values: fiercely innovative, open culture, purposeful urgency, passion for excellence, and commitment to people, and these values influence how we work and the business decisions we make. Thanks to feedback from our employees over the years, we’ve been fortunate to be named a top employer around the world. Alnylam is extremely proud to have been recognized as the #1 Large Employer by Boston

Globe Top Places to Work in 2022, one of Science Magazine’s Top Biopharma Employers, one of America's Most Responsible Companies for 2023 by Newsweek, a Fast Company Best Workplace for Innovators, and a Great Place to Work in Canada, France, Italy, Spain, Switzerland, and UK – among others.

At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. We are dedicated to building an environment where employees can feel that they belong, can bring their authentic selves to work, and achieve to their full potential. By empowering employees to embrace their unique differences at work, our business grows stronger with advanced and original thinking, allowing us to bring groundbreaking medicines to patients.

Qualified applicants will receive consideration for employment without regard to their race, color, religion, age, sex, sexual orientation, gender identity or expression, national origin, ethnicity, marital status, protected veteran status, disability, or any other characteristics prohibited by law. Alnylam is an E-Verify employer.

Senior scientist in DMPK department will be a highly motivated individual who will utilize their knowledge in drug metabolism, ADME concepts, pharmacokinetics, pharmacodynamic and bioanalytical principles to advance the discovery and preclinical development of Alnylam’s therapeutic siRNA programs. In this hands-on laboratory position the successful candidate will be responsible for selection and utilization of relevant in vitro and or in vivo models to evaluate ADME and pharmacokinetic properties to drive the progression of drug candidates into the clinic. The Sr. Scientist will collaborate closely with discovery, translational and clinical research.

Key Responsibilities 

• Design and execute preclinical studies to understand the pharmacokinetics (PK) and absorption, metabolism, distribution, and excretion (ADME) of drug candidates
• Responsible for the analysis, interpretation, integration and reporting of preclinical DMPK data generated both internally and with external vendors/academic sites
• Build and develop quantitative tools to translate PK/PD relationship from preclinical to clinical using modeling and simulation for siRNAs
• Participate in the management of CROs/academic sites in the conduct of in vitro/in vivo ADME studies
• Represent DMPK as the subject matter expert to Alnylam project teams
• Prepare strategic and scientifically sophisticated ADME strategies that meet regulatory requirements and program goals
• Author high quality regulatory documents including INDs, CTAs, and NDA filings. Partner with and support Toxicology, Research, Clinical, Regulatory, Project Management and other departments
• Participate in the preparation of abstracts and manuscripts for publication

Qualifications

• Ph.D. in Pharmacokinetics, Drug Metabolism, Pharmacology, Pharmaceutics, or other relevant field with >0+ years of experience or Masters with 10+ years experience in the biopharmaceutical industry
• Strong knowledge of drug metabolism, ADME concepts, pharmacokinetics, pharmacodynamic and bioanalytical principles
• Self-motivation, ability to work independently and excellent organization skills that enable working within timelines is required
• Desire to work hands-on in a lab setting essential.
• Proficient in using WinNonlin or other pharmacokinetic software
• Experience in the metabolism aspect of oligonucleotides (e.g., ASO, siRNA, etc.) is a plus
• Strong communication (verbal and written) and presentation skills required
• Excellent interpersonal skills and ability to represent DMPK in a team environment are essential

About Alnylam

Alnylam Pharmaceuticals (Nasdaq: ALNY) has led the translation of RNA interference (RNAi) into a whole new class of innovative medicines with the potential to transform the lives of people afflicted with rare and more prevalent diseases. Based on Nobel Prize-winning science, RNAi therapeutics represent a powerful, clinically validated approach to treating diseases at their genetic source by “interfering” with mRNA that cause or contribute to disease. Since our founding in 2002, Alnylam has led the RNAi Revolution and continues to turn scientific possibility into reality. 

Our people-first culture is guided by our core values: fiercely innovative, open culture, purposeful urgency, passion for excellence, and commitment to people, and these values influence how we work and the business decisions we make. Thanks to feedback from our employees over the years, we’ve been fortunate to be named a top employer around the world. Alnylam is extremely proud to have been recognized as the #1 Large Employer by Boston Globe Top Places to Work in 2022, one of Science Magazine’s Top Biopharma Employers, one of America's Most Responsible Companies for 2023 by Newsweek, a Fast Company Best Workplace for Innovators, and a Great Place to Work in Canada, France, Italy, Spain, Switzerland, and UK – among others.

At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. We are dedicated to building an environment where employees can feel that they belong, can bring their authentic selves to work, and achieve to their full potential. By empowering employees to embrace their unique differences at work, our business grows stronger with advanced and original thinking, allowing us to bring groundbreaking medicines to patients.

Qualified applicants will receive consideration for employment without regard to their race, color, religion, age, sex, sexual orientation, gender identity or expression, national origin, ethnicity, marital status, protected veteran status, disability, or any other characteristics prohibited by law. Alnylam is an E-Verify employer.

Summary of Key Responsibilities

• Assesses patients’ needs and develops action plans that provide for the initiation and continuation of treatment with Alnylam products while coordinating the exchange of all applicable patient-related information with appropriate internal and external stakeholders.
• Develops a comprehensive understanding of the reimbursement process, billing/coding nuances, insurance plans, payer trends, financial assistance programs, patient assistance programs, and related resources.
• Assists in obtaining insurance approval for Alnylam products, and proactively plans for maintenance of coverage by working with patients and their caregivers/families, healthcare providers, insurance companies, specialty pharmacies, and Alnylam colleagues.
• Understands the resources available in their specific region, and how they can be best employed to support patient care.
• Identifies complex patient-specific issues and develops and executes action plans accordingly.
• Maintains disease, reimbursement and insurance coverage expertise through continuing medical education and attendance at relevant conferences and other educational opportunities.
• Educates patients, caregivers, family members, health care providers, and others regarding insurance options and limitations, including requirements necessary to initiate and maintain treatment, patient services’ offerings and relevant disease/product information as necessary.
• Fosters collaborative relationships with all internal and external customers including but not limited to Patient Education Liaisons, medical, sales, field reimbursement, corporate accounts, patient advocacy, insurance company case managers, specialty pharmacies, home health agencies, and office coordinators.
• Maintains accurate data on each individual, their insurance, coverage approvals, on-going coverage requirements and all patient and provider interactions.
• Attend patient meetings and represent Alnylam at industry conferences, as needed
• Ensures compliance with all corporate and industry policies in collaboration with Alnylam Legal, Regulatory and Compliance.

Qualifications

• Bachelor’s Degree required. Health Care/Social Work/Nursing (or related field) a plus.
• 3+ years recent case management experience in the healthcare or pharmaceutical/biotech industry. Ultra-rare disease experience a plus.
• Experience should include but not be limited to home care management, case management review, utilization review, social service support, insurance reimbursement, patient assistance programs, or billing and coding.
• Knowledge of benefit verification and prior authorization process for infused and injectable products.
• Knowledge of private payer, Medicare, and Medicaid structure, systems, and reimbursement process required.
• Experience and proficiency in working with a Customer Relationship Management System, such as Salesforce.com.
• Possess strong written and verbal communication skills, exceptional listening, critical thinking, problem solving, negotiation and mediation skills.
• Ability to navigate difficult conversations and handle sensitive issues with opposing opinions.
• Ability to work independently and manage competing priorities.
• Experience working in cross-functional teams and effective in influencing without authority.
• Desire to innovate and work in a fast-paced, flexible, and energetic environment.
• Self-starter who is highly passionate about rare disease and Alnylam’s core values:
• Commitment to People, Innovation and Discovery, Sense of Urgency, Open Culture, and Passion for Excellence.
• Ability to travel 5%, including weekends/evenings, as needed.

About Alnylam

Alnylam Pharmaceuticals (Nasdaq: ALNY) has led the translation of RNA interference (RNAi) into a whole new class of innovative medicines with the potential to transform the lives of people afflicted with rare and more prevalent diseases. Based on Nobel Prize-winning science, RNAi therapeutics represent a powerful, clinically validated approach to treating diseases at their genetic source by “interfering” with mRNA that cause or contribute to disease. Since our founding in 2002, Alnylam has led the RNAi Revolution and continues to turn scientific possibility int
o reality. 

Our people-first culture is guided by our core values: fiercely innovative, open culture, purposeful urgency, passion for excellence, and commitment to people, and these values influence how we work and the business decisions we make. Thanks to feedback from our employees over the years, we’ve been fortunate to be named a top employer around the world. Alnylam is extremely proud to have been recognized as the #1 Large Employer by Boston Globe Top Places to Work in 2022, one of Science Magazine’s Top Biopharma Employers, one of America's Most Responsible Companies for 2023 by Newsweek, a Fast Company Best Workplace for Innovators, and a Great Place to Work in Canada, France, Italy, Spain, Switzerland, and UK – among others.

At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. We are dedicated to building an environment where employees can feel that they belong, can bring their authentic selves to work, and achieve to their full potential. By empowering employees to embrace their unique differences at work, our business grows stronger with advanced and original thinking, allowing us to bring groundbreaking medicines to patients.

Qualified applicants will receive consideration for employment without regard to their race, color, religion, age, sex, sexual orientation, gender identity or expression, national origin, ethnicity, marital status, protected veteran status, disability, or any other characteristics prohibited by law. Alnylam is an E-Verify employer.

The Commercial Operations Manager will be responsible to support in the development and execution of local Marketing & Operational activities in the BeNeLux, with main focus on the management of our portfolio, that include Amyloidosis (hATTR), Porphyria (AHP) and Primary Hyperoxauria Type 1 (PH1) products as well as other products in the pipeline. The manager will be responsible for several business essential systems, such as insights, forecasting and CRM. The role will support the Country Manager and Business Leads in cross-functional activities to ensure excellent alignment and communications from the BeNeLux team to the regional team. The Commercial Operations Manager will be reporting to the Country Manager and based in Amsterdam (hybrid).

 Key Responsibilities

• Support the Business Leads with the development and execution of country brand strategies and brand plans in the BeNeLux.
• Support the Commercial and Business Leads to develop and execute account plans.
• Assist with the design, production and approval of product promotional and disease education materials; collaborate with Legal, Regulatory, and Compliance stakeholders to ensure all marketing initiatives are executed in a compliant manner.
• Ensuring ongoing compliance of materials especially with regards to SmPC updates.
• Develop and maintain the team’s annual congress plan.
• Manage business essential system:
  • Consoloditate Business insights from the various disease areas, including competitor data and market insights.
  • Forecast Modelling.
  • Optimize targeting and CRM, including Sales Force Effectiveness.
  • Optimize Ordering and Supply management, including order files, contacts with pharmacies and internal Supply Chain and Finance departments.
  • GDPR assessments of relevant projects.
  • Vendor management, including contract management.
• Build strong relationships with other functional areas and internal strategic partners (i.e., Sales, Medical, Regulatory, Clinical, Legal, Regional Marketing, Business Operations etc.).
• Leverage best practices from within the global commercial organization and continually foster learning from industry best practices.
• Collaborate with legal, regulatory, and compliance stakeholders to ensure compliant development and execution of marketing initiatives.
• Update local dashboard to monitor KPIs.
• Work with the regional Transparency Coordinator to prepare and submit the annual transparency report in Belgium, Netherlands and Luxembourg.
• Any other activities as required to support the BeNeLux business.

Qualifications

• Life Science degree, Business degree a plus.
• Proven experience in bio/pharmaceutical marketing, rare disease arena is a plus.
• Experience in digital & Multichannel marketing is a plus.
• Fluency in Dutch and English is essential, French is a plus.
• The candidate should be able to manage multiple projects in different markets.
• Ability to engage cross-functional working groups and teams.
• Good project management skills.
• Strong communication skills.
• Positive attitude, enthusiastic approach.
• Willingness to travel to Belgium on a regular (e.g. monthly) basis.

About Alnylam

Alnylam Pharmaceuticals (Nasdaq: ALNY) has led the translation of RNA interference (RNAi) into a whole new class of innovative medicines with the potential to transform the lives of people afflicted with rare and more prevalent diseases. Based on Nobel Prize-winning science, RNAi therapeutics represent a powerful, clinically validated approach to treating diseases at their genetic source by “interfering” with mRNA that cause or contribute to disease. Since our founding in 2002, Alnylam has led the RNAi Revolution and continues to turn scientific possibility into reality. 

Our people-first culture is guided by our core values: fiercely innovative, open culture, purposeful urgency, passion for excellence, and commitment to people, and these values influence how we work and the business decisions we make. Thanks to feedback from our employees over the years, we’ve been fortunate to be named a top employer around the world. Alnylam is extremely proud to have been recognized as the #1 Large Employer by Boston Globe Top Places to Work in 2022, one of Science Magazine’s Top Biopharma Employers, one of America's Most Responsible Companies for 2023 by Newsweek, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the Netherlands,  France, Italy, Spain, Switzerland, and UK – among others.

At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. We are dedicated to building an environment where employees can feel that they belong, can bring their authentic selves to work, and achieve to their full potential. By empowering employees to embrace their unique differences at work, our business grows stronger with advanced and original thinking, allowing us to bring groundbreaking medicines to patients.

We are looking for an experienced and talented Business Account Executive (BAE) to commercially represent GIVLAARI®  and OXLUMO® in the United States and have a significant impact on the lives of AHP patients. AHP’s represent a sub-group of Porphyrias, characterized by the occurrence of neuro-visceral attacks with or without cutaneous manifestations. AHP’s include four disorders: acute intermittent porphyria (the most common), variegate porphyria, hereditary coproporphyria, and a genetic deficit of delta-aminolaevulinic acid dehydratase. PH1 is a rare, life-threatening disease that can cause serious damage to kidneys and progressively to other organs. PH1 is a little-known condition and patients often spend years undiagnosed and misdiagnosed.

The BAE will be principally responsible for driving physician and patient identification, disease awareness, overall market development, and brand awareness within their ascribed territory. The BAE will be responsible for achieving territory targets and other business objectives through account and customer strategies, while also partnering & collaborating very closely with internal and external stakeholders to effectively manage all aspects of the regional business. The achievement of targets will be based in Alnylam’s values: our commitment to people, sense of urgency, passion for excellence, innovation & discovery, and open culture as well as our unwavering commitment to integrity.

The BAE will report to the Regional Business Director (RBD) for their respective region.   

Key Responsibilities

• Drive patient identification through appropriate HCP driven strategies including market development, increase brand awareness through building and executing a territory strategy/account plan; continuously assess opportunities within markets and accounts to launch successfully.
• Effectively prioritize and manage time, activities, and resources in order to optimize access to academic and community HCPs.
• Build and maintain relationships with HCPs and office staff by maximizing their time through planning, leveraging insights, and conducting post-call analysis refining tactics based on opportunities.
• Proactively build effective working relationships with internal/external stakeholders; drive agreement/decisions from multiple stakeholders; demonstrated high level of emotional intelligence adapting communication based on different stakeholders.
• Collaborate with stakeholders across all commercial departments including; patient services, field reimbursement, and others to ensure access at site of care and that logistics are in place to administer medications.
• Collaborate with key accounts and physicians to build individual account plans to drive patient identification through market development and physician education; achieve sales goals, and maintain relationships in order to maximize sales results.
• Execute speaker programs, local sponsorships, displays and exhibits, both in and out of office across multiple account types: academic institutions, physician offices, infusion centers, and alternate site locations.
• Routinely report territory-level market dynamics and trends, including prescriber opinion and competitive activity to RBD as required.

Qualifications

• Bachelor’s required: MBA/Science Degree preferred.
• 7+ years of demonstrated success in biotech, specialty pharmaceuticals, or medical devices.
• Recent rare/ultra-rare disease experience within the past 5 years.
• Deep experience, success and relationships in Gastroenterology, Hepatology, Neurology, Hematology/Oncology Nephrology and/or Urology are important and strongly preferred. 
• Pediatric Hospital/Institution knowledge and expertise with pharmacy formulary processes.
• Drive to serve the unmet needs of patients with an ultra-rare disease.
• Buy & Bill, Miscellaneous J code product launch experience required including a working knowledge of government and commercial payers including Medicare B and D.
• Understanding and experience working with HUB patient services required.
• Thorough understanding of site of care identification, development and education.
• Hospital / Institution knowledge and expertise with pharmacy formulary processes in academic settings.
• Experience supporting biologic therapy administered by designated HCPs preferred.
• Experience driving, leading and delivering upon territory-level cross functional business planning.
• Must be familiar with relevant legal and regulatory environment in biotech/pharmaceutical industry.
• Strong communication and listening skills.
• Effective at managing complex individualized cases in a compliant manner.
• Overnight travel required including travel to Boston, congresses and large geographical territories
• Candidates must have a valid driver's license.
• Must live within 50 miles of the assigned territory.

About Alnylam

Alnylam Pharmaceuticals (Nasdaq: ALNY) has led the translation of RNA interference (RNAi) into a whole new class of innovative medicines with the potential to transform the lives of people afflicted with rare and more prevalent diseases. Based on Nobel Prize-winning science, RNAi therapeutics represent a powerful, clinically validated approach to treating diseases at their genetic source by “interfering” with mRNA that cause or contribute to disease. Since our founding in 2002, Alnylam has led the RNAi Revolution and continues to turn scientific possibility into reality. 

Our people-first culture is guided by our core values: fiercely innovative, open culture, purposeful urgency, passion for excellence, and commitment to people, and these values influence how we work and the business decisions we make. Thanks to feedback from our employees over the years, we’ve been fortunate to be named a top employer around the world. Alnylam is extremely proud to have been recognized as the #1 Large Employer by Boston Globe Top Places to Work in 2022, one of Science Magazine’s Top Biopharma Employers, one of America's Most Responsible Companies for 2023 by Newsweek, a Fast Company Best Workplace for Innovators, and a Great Place to Work in Canada, France, Italy, Spain, Switzerland, and UK – among others. 

At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. We are dedicated to building an environment where employees can feel that they belong, can bring their authentic selves to work, and achieve to their full potential. By empowering employees to embrace their unique differences at work, our business grows stronger with advanced and original thinking, allowing us to bring groundbreaking medicines to patients. 

Qualified applicants will receive consideration for employment without regard to their race, color, religion, age, sex, sexual orientation, gender identity or expression, national origin, ethnicity, marital status, protected veteran status, disability, or any other characteristics prohibited by law. Alnylam is an E-Verify employer.

The Medical Science Liaison is responsible for managing and executing field medical activities that support the Medical Affairs strategies for marketed products and/or development compounds. They use clinical knowledge and field expertise along with business orientation to identify and communicate business and scientific trends in the healthcare environment. They engage in peer coaching across the Field team and are sought out by peers and colleagues to inform the medical strategy with identified market and healthcare trends. The Medical Science Liaison will understand the external healthcare environment and data gaps related to the disease area or product; gather field intelligence, identify and communicate key insights to internal colleagues; and fulfil stakeholder information needs by communicating appropriate details of therapeutic area and product/compound. The ideal candidate will possess an understanding of rare and prevalent diseases development and a strong sense of science and business acumen.

Key Responsibilities

• Provide accurate and fair-balanced scientific and medical information (clinical data, development, publications...) upon request, according to the needs of experts or healthcare professionals, through individual interviews or scientific meetings.
• Provide scientific support and attendance at conferences and meetings.
• Ensure relevant and appropriate responses to customer medical inquiries for example medical commissions of hospitals, in charge of the proper use of the drug.
• Participate in regional events, national and international congresses.
• Identify medical experts and institutional networks (care decision-makers, public health organizations...) of his/her area of ​​expertise in his/her region and optimize relations with the medical community.
• Analyze all the environmental characteristics of the therapeutic areas of Alnylam.
• Implement and monitor regional medical plans.
• Guarantee the scientific and ethical quality of the projects.
• Set up, in partnership with the expert healthcare professionals in his/her region, regional non-promotional medical operations.
• Gather and animate groups of experts (boards) to elaborate his/her projects.
• Set up programs aimed at optimizing the care of the patient (care networks, information programs, observatories...).
• Establish and maintain peer-to-peer relationships to build awareness, proper use and investigate new uses of Alnylam’s products.
• Identify and select the scientific study projects proposed by clinicians in his/her region.
• Participate in the implementation and monitoring of studies carried out by the company, in support of headquarters teams and clinical operations.
• Provide a field medical interface in the context of EAP (AP1 and AP2) program and CPC.
• Be the medical referent in the region: offers scientific expertise, ensures proper use of medicines.
• Ensure an effective interface between the Field and the Headquarters especially in terms of competitive intelligence, regular feedback on the evolution of the market, competition, the environment and the perception of products and services by healthcare professionals.
• Update knowledge and participate in the training of field sales teams in the therapeutic area.
• Maintain a level of expertise in the evolving scientific / therapeutic area and in competitor medicines.
• Non-promotional communication with healthcare professionals, respecting the principles of separation of promotional and non-promotional activities defined by the promotional information charter.
• Good Clinical Practices.
• Rules of professional conduct of Alnylam France.
• Rules on the transparency of links and especially with healthcare professionals, students and associations.
• Ensure DMOS law application.
• Be compliant to Ethics, Compliance and internal policies.
• Report adverse events according to company policy 

Qualifications

• Scientific background.
• Experience in Medical Affairs and MSL roles.
• Experience in cardiology area.
• Experience with literature review, synthesis and analysis.
• Experience in public presentation required.
• Ability to organize and prioritize own work schedule.

About Alnylam

Alnylam Pharmaceuticals (Nasdaq: ALNY) has led the translation of RNA interference (RNAi) into a whole new class of innovative medicines with the potential to transform the lives of people afflicted with rare and more prevalent diseases. Based on Nobel Prize-winning science, RNAi therapeutics represent a powerful, clinically validated approach to treating diseases at their genetic source by “interfering” with mRNA that cause or contribute to disease. Since our founding in 2002, Alnylam has led the RNAi Revolution and continues to turn scientific possibility into reality. 

Our people-first culture is guided by our core values: fiercely innovative, open culture, purposeful urgency, passion for excellence, and commitment to people, and these values influence how we work and the business decisions we make. Thanks to feedback from our employees over the years, we’ve been fortunate to be named a top employer around the world. Alnylam is extremely proud to have been recognized as the #1 Large Employer by Boston Globe Top Places to Work in 2022, one of Science Magazine’s Top Biopharma Employers, one of America's Most Responsible Companies for 2023 by Newsweek, a Fast Company Best Workplace for Innovators, and a Great Place to Work in Canada, France, Italy, Spain, Switzerland, and UK – among others. 

At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. We are dedicated to building an environment where employees can feel that they belong, can bring their authentic selves to work, and achieve to their full potential. By empowering employees to embrace their unique differences at work, our business grows stronger with advanced and original thinking, allowing us to bring ground breaking medicines to patients. 

Key Responsibilities

• Partner closely with investigators and internal stakeholders to drive patient accrual. Partner closely with investigators and internal stakeholders as   needed regarding Alnylam clinical trials.
• Identify key opinion leaders and cultivate a network of experts for key Alnylam disease areas. 
• Develop, maintain, and execute US KOL and US Institution plans within respective geography.
• Conduct and implement a comprehensive disease awareness tactical plan within the respective geography. 
• Collaborate with health care professionals to identify opportunities for the development of algorithms and guidelines to facilitate early diagnosis
• Provide in-depth drug mechanism of action and emerging clinical information to health care providers in the respective geography. 
• Serve as a liaison to health care professionals and professional organizations and disease state advocacy groups.  Support the efforts of patient support groups and educational foundations. 
• Provide medical and scientific input into the planning and execution of advisory boards and work with experts to review speaker presentations and   provide additional medical background where requested.
• Contribute to Alnylam's achievement of Company objectives for pre-approved products.
• Provide educational meeting support at scientific congresses.
• Coordinate required medical, legal, and regulatory review and approval of all field documents for distribution or presentation.
• Requires 60-70% travel.

Qualifications

• PhD, PharmD, DNP, PA or MD with 3 to 5 years’ industry experience.
• Proven basic science and/or clinical background to enable engagement of Health Care Professionals in a scientifically meaningful exchange.
• Prior experience in rare disease, cardiology or neurology strongly preferred.
• Experience in clinical research, patient recruitment, and investigator-sponsored trials.
• Experience in medical education and KOL management.
• Effective communication of evidence based scientific information.
• Ability to work collaboratively and cross-functionally.
• Capable of managing shifting priorities in a rapidly changing and environment
• Decision-making and accountability.
• Clear alignment with Alnylam Core Values
  • Commitment to People
  • Fiercely Innovative
  • Purposeful Sense of Urgency
  • Open Culture
  • Passion for Excellence

About Alnylam

Alnylam Pharmaceuticals (Nasdaq: ALNY) has led the translation of RNA interference (RNAi) into a whole new class of innovative medicines with the potential to transform the lives of people afflicted with rare and more prevalent diseases. Based on Nobel Prize-winning science, RNAi therapeutics represent a powerful, clinically validated approach to treating diseases at their genetic source by “interfering” with mRNA that cause or contribute to disease. Since our founding in 2002, Alnylam has led the RNAi Revolution and continues to turn scientific possibility into reality. 

 Our people-first culture is guided by our core values: fiercely innovative, open culture, purposeful urgency, passion for excellence, and commitment to people, and these values influence how we work and the business decisions we make. Thanks to feedback from our employees over the years, we’ve been fortunate to be named a top employer around the world. Alnylam is extremely proud to have been recognized as the #1 Large Employer by Boston Globe Top Places to Work in 2022, one of Science Magazine’s Top Biopharma Employers, one of America's Most Responsible Companies for 2023 by Newsweek, a Fast Company Best Workplace for Innovators, and a Great Place to Work in Canada, France, Italy, Spain, Switzerland, and UK – among others.

 At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. We are dedicated to building an environment where employees can feel that they belong, can bring their authentic selves to work, and achieve to their full potential. By empowering employees to embrace their unique differences at work, our business grows stronger with advanced and original thinking, allowing us to bring groundbreaking medicines to patients.

Qualified applicants will receive consideration for employment without regard to their race, color, religion, age, sex, sexual orientation, gender identity or expression, national origin, ethnicity, marital status, protected veteran status, disability, or any other characteristics prohibited by law. Alnylam is an E-Verify employer.

Medical Research designs and drives the operational strategy of medical affairs studies in order to generate robust real-world evidence that provides further insight on disease diagnosis and utilization, safety and clinical effectiveness of approved treatments.

The Sr. Manager, Medical Research is responsible for managing and coordinating of operational activities for medical affairs studies including global phase IV clinical trials, local/regional studies and patient registries. The role will assist in executing ongoing and future studies and will support the successful implementation and management of the operational aspects of these programs.

Key Responsibilities

• Provide organizational and project support by working directly with cross-functional individuals and teams to coordinate and execute activities related to key medical affairs studies
• Effectively and efficiently interact with internal, clinical site, and vendor personnel to track activities and milestones related to the conduct of medical affairs studies
• Work as part of an internal team to contribute to the development of program-specific plans and materials. Review and maintain plans generated by CROs and vendors
• Develops and maintains the relationship with the CRO to effectively execute the assigned responsibilities
• Demonstrate problem-solving skills, including the identification of problems and proposed solutions, in consultation with more senior team members
• Work with legal and compliance to support organization and maintenance of standard operating procedures
• Coordinate development of agendas and maintain oversight of action items from program team (internal) and vendor meetings to drive execution of key initiatives and facilitate decision-making
• Demonstrate problem-solving skills, including the proactive identification of issues and proposed solutions, in consultation with more senior team members
• Support and/or drive the development and review of specific study documents e.g. informed consent forms, CRFs, manuals, training materials
• Support in the development of action plans to address protocol compliance, safety, data and administrative issues with sites and supporting vendors
• Management of study budgets, including annual budget planning

Qualifications

• BA/BS in life sciences or equivalent. Advanced degree or certification a plus.
• Proven experience in the pharmaceutical/biotech industry, prior experience in Clinical Operations and/or Medical Affairs managing GCP/GPP studies.
• Knowledge of ICH/GCP, regulatory guidelines/directives, and drug development and clinical research processes
• Scientific learning agility to quickly develop a sound working knowledge of new therapeutic areas
• Prior CRO oversight experience is highly preferred
• Must be able to actively manage and track many complex projects in parallel, managing the actions of many people toward shared outcomes
• Excellent communication skills and relationship building capabilities
• Strong team player that has a customer service approach and is solution oriented
• Attention to detail and the ability to work independently, within a multi-disciplinary team, as well as with external partners and vendors
• Clear alignment with Alnylam Core Values
  

About Alnylam

Alnylam Pharmaceuticals (Nasdaq: ALNY) has led the translation of RNA interference (RNAi) into a whole new class of innovative medicines with the potential to transform the lives of people afflicted with rare and more prevalent diseases. Based on Nobel Prize-winning science, RNAi therapeutics represent a powerful, clinically validated approach to treating diseases at their genetic source by “interfering” with mRNA that cause or contribute to disease. Since our founding in 2002, Alnylam has led the RNAi Revolution and continues to turn scientific possibility into reality. 

Our people-first culture is guided by our core values: fiercely innovative, open culture, purposeful urgency, passion for excellence, and commitment to people, and these values influence how we work and the business decisions we make. Thanks to feedback from our employees over the years, we’ve been fortunate to be named a top employer around the world. Alnylam is extremely proud to have been recognized as the #1 Large Employer by Boston Globe Top Places to Work in 2022, one of Science Magazine’s Top Biopharma Employers, one of America's Most Responsible Companies for 2023 by Newsweek, a Fast Company Best Workplace for Innovators, and a Great Place to Work in Canada, France, Italy, Spain, Switzerland, and UK – among others.

At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. We are dedicated to building an environment where employees can feel that they belong, can bring their authentic selves to work, and achieve to their full potential. By empowering employees to embrace their unique differences at work, our business grows stronger with advanced and original thinking, allowing us to bring groundbreaking medicines to patients.

Qualified applicants will receive consideration for employment without regard to their race, color, religion, age, sex, sexual orientation, gender identity or expression, national origin, ethnicity, marital status, protected veteran status, disability, or any other characteristics prohibited by law. Alnylam is an E-Verify employer.

The Director, Legal Counsel will be a member of the Global R&D Legal practice area.  Global R&D Legal supports three key Alnylam functions:  Research Development (ReDev), Development /Medical Affairs (DMA), and Global Technical Operations and Quality (TOQ).   This role’s primary focus will be supporting TOQ (Manufacturing, Supply Chain, Quality, CMC, Facilities) while also supporting ReDev and DMA, as assigned.  This role will report to the Vice President, Global Research & Development Legal. 

This is a hybrid role that requires periodic in-person engagement with a large TOQ organization in Cambridge, MA and Norton, MA. 

Key Responsibilities

Legal Support for Global Technical Operations and Quality (TOQ)

• Provide legal advisory and strategic support to Global TOQ team (Manufacturing, Supply Chain, Quality, CMC, and Facilities).
• Partner with TOQ, Clinical Development, Commercial, Legal, Ethics & Compliance and other business colleagues worldwide to (i) advise and help implement TOQ business strategy, (ii) structure applicable transactions that deliver on that strategy, and (iii) negotiate and execute agreements in accordance with those requirements and the company’s overall objectives, priorities and policies.
• Serve as a key resource to address legal and contracting issues related to Alnylam’s global clinical and commercial supply chains. 
• Participate in cross-functional team meetings to ensure TOQ business partners are achieving targeted goals 
• Review and negotiate TOQ agreements (Supply Agreements, MSAs, Packaging and Labeling Agreements, Distribution Agreements).

Overall Legal Support for Alnylam’s R&D Functions (ReDev, DMA, TOQ)

• Partner with Global R&D Legal colleagues to provide comprehensive legal support to Alnylam’s R&D functions.
• Provide legal, business and strategic advice on relationship support by interpreting contract language for internal business partners to help avoid and/or resolve potential issues.  Also, partner with business partners on managing third party relationships. 
• Provide best-in-class legal support for policies, processes, templates, governance principles and support structures that allow Alnylam to successfully grow and scale globally.
• Partner with IP Legal and Business Development Legal to address potential IP issues and support Alnylam’s relationships with collaborators, respectively.
• Partner cross-functionally and collaborate with business and legal stakeholders acting as enterprise connector to ensure global excellence, consistency and compliance with all R&D activities.
• Contribute to process improvements across our Legal department and organization, as needed.
• Identify and effectively communicate priorities and urgencies to applicable stakeholders.

Qualifications

• Juris Doctor degree required;  An advanced science degree in chemistry or other area relevant to TOQ is preferred
• Minimum 7+ years’ experience dedicated to drafting, negotiating, and advising on TOQ matters with an emphasis on drafting/negotiating agreements and advising on all TOQ areas (in-house and/or a nationally recognized law firm).
• Experience in partnering with TOQ business partners to provide advisory and strategic support.
• Experience or knowledge in supporting Early Development and/or Development/Medical Affairs organizations
• Demonstrated exceptional communication skills, including presentation, interpersonal interactions, and written communications
• Experience effectively working with all levels in the organization
• Demonstrated commitment to finding solutions, relationship building, continued learning, proactivity and a high sense of confidentiality
• Excellent interpersonal skills that are demonstrated by being articulate, direct and forthright, and serving as a collaborative and decisive team member and a strategic thinker with a broad perspective
• Ability to manage and prioritize multiple matters simultaneously and to respond to rapidly shifting priorities in ambiguous or challenging situations
• Willing to support any areas of Global R&D, as needed. 
• Demonstrated ability to own projects and consistently meet tight timing requirements and high quality standards
• Strong verbal and written communication skills, including proven ability to interact and communicate effectively with individuals from multiple departments at all levels of the organization

About Alnylam

Alnylam Pharmaceuticals (Nasdaq: ALNY) has led the translation of RNA interference (RNAi) into a whole new class of innovative medicines with the potential to transform the lives of people afflicted with rare and more prevalent diseases. Based on Nobel Prize-winning science, RNAi therapeutics represent a powerful, clinically validated approach to treating diseases at their genetic source by “interfering” with mRNA that cause or contribute to disease. Since our founding in 2002, Alnylam has led the RNAi Revolution and continues to turn scientific possibility into reality. 

Our people-first culture is guided by our core values: fiercely innovative, open culture, purposeful urgency, passion for excellence, and commitment to people, and these values influence how we work and the business decisions we make. Thanks to feedback from our employees over the years, we’ve been fortunate to be named a top employer around the world. Alnylam is extremely proud to have been recognized as the #1 Large Employer by Boston Globe Top Places to Work in 2022, one of Science Magazine’s Top Biopharma Employers, one of America's Most Responsible Companies for 2023 by Newsweek, a Fast Company Best Workplace for Innovators, and a Great Place to Work in Canada, France, Italy, Spain, Switzerland, and UK – among others.

At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. We are dedicated to building an environment where employees can feel that they belong, can bring their authentic selves to work, and achieve to their full potential. By empowering employees to embrace their unique differences at work, our business grows stronger with advanced and original thinking, allowing us to bring groundbreaking medicines to patients.

Qualified applicants will receive consideration for employment without regard to their race, color, religion, age, sex, sexual orientation, gender identity or expression, national origin, ethnicity, marital status, protected veteran status, disability, or any other characteristics prohibited by law. Alnylam is an E-Verify employer.

The Director, Public Policy will be an integral part of a high-performing team, reporting to the Senior Director, Global Public Policy & Government Relations. Based in Cambridge, MA, the Director will support the strategic vision of Alnylam as a leader in RNAi. 

The successful candidate will have a “roll up your sleeves” and collaborative approach to work within a fast-paced, dynamic environment. 

This role will focus on several key areas for Alnylam’s success, particularly related to drug pricing and public payer coding, coverage, and reimbursement policies to ensure access to Alnylam’s RNAi therapeutics and an operating environment that fosters innovation. While this role will largely focus on US access-related policies, the role may also include opportunities for expansion into global public policy and/or tax, trade, IP, or regulatory policy, depending on a candidate’s skillset and interest.

Key Responsibilities

• Lead internal-facing public policy and public payer strategies to support commercial and corporate goals and objectives, including but not limited to serving as serving as public policy and public payer expert on access and marketing workstreams and partnering with colleagues to identify potential strategies to support commercial and corporate goals.
• Provide high quality strategic input and tactical support regarding public policy as well as coverage, coding, and reimbursement for public payers to global and regional program (product) teams, including Commercial, Medical Affairs, Regulatory Affairs and Legal, to ensure optimal patient access throughout the product lifecycle.
• Foster relationships with cross-functional partners to help drive policy development that is aligned with Commercial and Corporate strategy.
• Monitor external policy development and industry trends to identify priorities, opportunities and risks to Alnylam.
• Develop and present overviews and analyses of public policy priorities with impact on Alnylam to a range of audiences. 

• Drive policy strategy development on federal legislative and regulatory matters.
• Lead comment letters development and engagement on proposed federal regulations.
• Support internal functions through consultation and training on specific policy issues.
• Manage public policy vendors.
• Engage and support trade associations (BIO) and other industry partners to advance Alnylam’s policy positions.
• Lead key Global Public Policy & Government Relations (GPPGR) projects, as needed.
• Grow and refine a deep understanding of Alnylam’s RNAi platform technology, programs and patient populations, and communicate and translate this knowledge effectively and appropriately to a variety of audiences.

Qualifications

• Bachelor’s Degree Required, Graduate Degree in Public Policy, Public Health or an MBA is preferred
• 10+ Years of work experience required, preferably in biotech, pharmaceuticals or healthcare.
• In-depth background in the analysis of federal government processes, laws, and regulations, particularly Medicare Part B and Part D required
• Strong understanding of coverage in public programs, including Medicare and Medicaid, required. Knowledge of Affordable Care Act coverage requirements required.
• Demonstration of substantial policy writing required.
• Desire and interest to be a “content creator” with strong presentation skills, and ability to simplify complex issues in writing.
• Ability to lead meetings effectively with external or internal partners, including ability to communicate effectively with executives.
• Experience in governmental engagement preferred.
• Strong project management, analytical, and business skills required. Experience managing vendors to execute on consulting work is preferred.
• Demonstrated track record of being able to work effectively in a cross-functional role and influence without authority.
• Meticulous attention to detail and commitment to high quality work product.
• Ability to work in a deadline-driven and fast-paced environment including managing multiple projects with on time.
• Strong relationship management, collaboration, and interpersonal skills are essential.
• Proficiency in Microsoft Office (PowerPoint, Excel, Word).
• Travel 10%. 

About Alnylam

Alnylam Pharmaceuticals (Nasdaq: ALNY) has led the translation of RNA interference (RNAi) into a whole new class of innovative medicines with the potential to transform the lives of people afflicted with rare and more prevalent diseases. Based on Nobel Prize-winning science, RNAi therapeutics represent a powerful, clinically validated approach to treating diseases at their genetic source by “interfering” with mRNA that cause or contribute to disease. Since our founding in 2002, Alnylam has led the RNAi Revolution and continues to turn scientific possibility into reality. 

Our people-first culture is guided by our core values: fiercely innovative, open culture, purposeful urgency, passion for excellence, and commitment to people, and these values influence how we work and the business decisions we make. Thanks to feedback from our employees over the years, we’ve been fortunate to be named a top employer around the world. Alnylam is extremely proud to have been recognized as the #1 Large Employer by Boston Globe Top Places to Work in 2022, one of Science Magazine’s Top Biopharma Employers, one of America's Most Responsible Companies for 2023 by Newsweek, a Fast Company Best Workplace for Innovators, and a Great Place to Work in Canada, France, Italy, Spain, Switzerland, and UK – among others.

At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. We are dedicated to building an environment where employees can feel that they belong, can bring their authentic selves to work, and achieve to their full potential. By empowering employees to embrace their unique differences at work, our business grows stronger with advanced and original thinking, allowing us to bring groundbreaking medicines to patients.

Qualified applicants will receive consideration for employment without regard to their race, color, religion, age, sex, sexual orientation, gender identity or expression, national origin, ethnicity, marital status, protected veteran status, disability, or any other characteristics prohibited by law. Alnylam is an E-Verify employer.

This  Senior Manager, Public Policy & Government Relations will oversee analytics, operations & communications and will be an integral part of a high-performing team, reporting to the Senior Director, Global Public Policy & Government Relations. 

Based in Cambridge, MA, the Senior Manager will advance legislative and regulatory priorities at the federal and state level that impact Alnylam and the patients we serve.  The position will lead public policy and public payer (e.g., Medicare) quantitative and qualitative analysis, and develop content to support Alnylam’s public policy priorities, commercial and corporate objectives. The position will also be responsible for supporting the operations of Alnylam’s political education and engagement programs, as well as Alnylam’s grassroots and public affairs efforts. 

While this role will largely focus on US access-related policies, the role may also include opportunities for expansion into global public policy and/or tax, trade, IP, or regulatory policy, depending on a candidate’s skillset and interest.

The successful candidate will be expected to have a positive, “roll your sleeves up” attitude and desire to tackle a range public policy issues to help support the GPPGR team 

Key Responsibilities

Public Policy Analysis

• Undertake policy analysis for myriad public policy matters impacting Alnylam and the biotech industry more generally, including the assessment of proposed legislation (e.g., proposed changes to Medicare and/or Medicaid) and regulations (e.g., annual Medicare payment rules)
• Serve as public payer coverage, coding, and reimbursement subject matter expert on relevant brand teams, where appropriate
• Develop primary analysis using quantitative and qualitative approaches, in partnership with internal and external teams to evaluate the potential opportunities and implications for, and impacts to Alnylam to support critical business decisions
• Work collaboratively with Global Public Policy & Government Relations (GPPGR), Legal, Regulatory, and Commercial colleagues to convert Alnylam’s policy and program priorities into timely and effective advocacy strategies to shape policy outcomes
• Support the development of materials and planning for engagement with federal and state governmental entities
• Monitor and assess the policy and regulatory landscape for potential issues with direct relevance to Alnylam and our customers
• Perform basic legislative and regulatory research

Public Policy Operations

• Support Political Action Committee (PAC) operations, including timely and compliant filing of reports through coordination with internal Alnylam stakeholders and outside legal counsel
• Develop and maintain GPPGR-related internal websites
• Develop and maintain Alnylam PAC internal supporting materials
• Develop briefing materials for Alnylam Executive engagements in DC and state capitols with elected officials

Public Policy Communications

• Develop Federal and state-level public policy summaries (largely via PowerPoint) to communicate to internal audiences
• Create ad hoc summaries of GPPGR engagement on specific policy issues to update Alnylam leadership and internal colleagues on areas of active policy engagement and advocacy
• Draft materials (largely using PowerPoint) to clearly communicate complex policy issues with impact on Alnylam to multiple audiences – both internal and external
• Create and manage the development and internal publication of the GPPGR Policy Updates
• Support engagement with industry trade associations and other third-party advocacy groups to advocate for desired policies that enable access to Alnylam therapies
• Support development of Alnylam’s public affairs efforts to advance public policy priorities 

Qualifications

• Bachelor’s Degree required; Graduate Degree preferred
• 6+ Years of work experience required, preferably in consulting, biopharmaceuticals, health care or public policy. Experience working within the pharmaceutical industry strongly preferred.
• Strong knowledge of government processes, laws, and regulations.
• Experience as a “content creator” with strong analytic skills, as well as outstanding writing and PowerPoint ability, and know-how to simplify complex political or regulatory requirements in writing
• Aptitude to provide internal stakeholders with timely, accurate and well written information to communicate opportunities, threats, and business interests from emerging public policy issues
• Understanding of Medicare and the Inflation Reduction Act are required. Knowledge of Medicaid, Affordable Care Act, Commercially-insured and state-regulated insurance markets and drug pricing methodologies a plus.
• Ability to manage and prioritize multiple issues and tasks and meet tight deadlines
• Ability to perform a cross-cutting role that interacts with numerous business areas such as market access, marketing, legal, patient advocacy, regulatory, and finance. She/he must be able to work effectively with a wide range of internal stakeholders
• Meticulous attention to detail and commitment to high quality and timely work product
• Excellent written and oral communication skills, including experience with executive-style communications
• Ability to manage vendors
• Strong relationship management and interpersonal skills are essential

About Alnylam

Alnylam Pharmaceuticals (Nasdaq: ALNY) has led the translation of RNA interference (RNAi) into a whole new class of innovative medicines with the potential to transform the lives of people afflicted with rare and more prevalent diseases. Based on Nobel Prize-winning science, RNAi therapeutics represent a powerful, clinically validated approach to treating diseases at their genetic source by “interfering” with mRNA that cause or contribute to disease. Since our founding in 2002, Alnylam has led the RNAi Revolution and continues to turn scientific possibility into reality. 

Our people-first culture is guided by our core values: fiercely innovative, open culture, purposeful urgency, passion for excellence, and commitment to people, and these values influence how we work and the business decisions we make. Thanks to feedback from our employees over the years, we’ve been fortunate to be named a top employer around the world. Alnylam is extremely proud to have been recognized as the #1 Large Employer by Boston Globe Top Places to Work in 2022, one of Science Magazine’s Top Biopharma Employers, one of America's Most Responsible Companies for 2023 by Newsweek, a Fast Company Best Workplace for Innovators, and a Great Place to Work in Canada, France, Italy, Spain, Switzerland, and UK – among others.

At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. We are dedicated to building an environment where employees can feel that they belong, can bring their authentic selves to work, and achieve to their full potential. By empowering employees to embrace their unique differences at work, our business grows stronger with advanced and original thinking, allowing us to bring groundbreaking medicines to patients.

Qualified applicants will receive consideration for employment without regard to their race, color, religion, age, sex, sexual orientation, gender identity or expression, national origin, ethnicity, marital status, protected veteran status, disability, or any other characteristics prohibited by law. Alnylam is an E-Verify employer.

The Associate Director, Biostatistics is responsible for statistical activities in support of clinical trials, including contributing to trial designs, authoring statistical sections of protocols, preparing statistical analysis plans, and reviewing and interpreting the analysis of clinical trial data.

Key Responsibilities

• Represents biostatistics at cross-functional team meetings to drive clinical development of drug candidate and provides input on clinical development plans.
• Collaborates with Clinical Development, Regulatory and Clinical Operations Expertise Areas to design clinical trials.
• Writes the statistical sections of clinical trial protocols, while consulting with internal and external experts.
• Contributes to or prepares statistical analysis plans.
• Collaborates with Data Management, Clinical Development and Clinical Operations on design of eCRFs.
• Provides statistical guidance on conduct of ongoing trials.
• Collaborates with Statistical Programmers on summary and analysis of trial data.
• Writes ADS and ad hoc analysis specifications.
• Contributes to clinical study reports and other regulatory documents e.g. DSURs, Briefing Documents, etc.
• Represents Alnylam in meetings with regulators, Key Opinion Leaders, partners, and other stakeholders
• Contributes to scientific articles, summarizing data collected in Alnylam trials.
• Participates in other activities and meetings to support Biostatistics and the Development Team as needed.
• Consults with Research & Preclinical colleagues on statistical questions in their work.
• Manages CRO statistical and programming support.

Qualifications

• Ph.D. in Biostatistics or Statistics or Equivalent with at least 7 years pharmaceutical biostatistics experience; or MS with at least 10 years relevant experience.
• Excellent written and oral communication and presentation skills.
• Experience programming in SAS.
• Interest in and basic understanding of biology and biological processes, including RNAi.

Desired Experience:

• Experience in clinical development through Phase 3 (NDA submission).
• Experience as lead statistician for a compound
• Understanding of ICH GCP as well as general knowledge of industry practices and standards.
• Proficiency in R programming language and other statistical software, including EAST.
• Experience with CDISC, including SDTM, ADaM, CDASH.
• Experience in representing sponsors in meetings with interaction with US FDA and international regulatory authorities.
• Experience designing and conducting adaptive trials.

About Alnylam

Alnylam Pharmaceuticals (Nasdaq: ALNY) has led the translation of RNA interference (RNAi) into a whole new class of innovative medicines with the potential to transform the lives of people afflicted with rare and more prevalent diseases. Based on Nobel Prize-winning science, RNAi therapeutics represent a powerful, clinically validated approach to treating diseases at their genetic source by “interfering” with mRNA that cause or contribute to disease. Since our founding in 2002, Alnylam has led the RNAi Revolution and continues to turn scientific possibility into reality. 

Our people-first culture is guided by our core values: fiercely innovative, open culture, purposeful urgency, passion for excellence, and commitment to people, and these values influence how we work and the business decisions we make. Thanks to feedback from our employees over the years, we’ve been fortunate to be named a top employer around the world. Alnylam is extremely proud to have been recognized as the #1 Large Employer by Boston Globe Top Places to Work in 2022, one of Science Magazine’s Top Biopharma Employers, one of America's Most Responsible Companies for 2023 by Newsweek, a Fast Company Best Workplace for Innovators, and a Great Place to Work in Canada, France, Italy, Spain, Switzerland, and UK – among others.

At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. We are dedicated to building an environment where employees can feel that they belong, can bring their authentic selves to work, and achieve to their full potential. By empowering employees to embrace their unique differences at work, our business grows stronger with advanced and original thinking, allowing us to bring groundbreaking medicines to patients.

Qualified applicants will receive consideration for employment without regard to their race, color, religion, age, sex, sexual orientation, gender identity or expression, national origin, ethnicity, marital status, protected veteran status, disability, or any other characteristics prohibited by law. Alnylam is an E-Verify employer.

Key Responsibilities

• Collaborates with Medical Affairs (Medical Research and Value, Evidence & Strategy), Medical Communications and Publications, Epidemiology and Regulatory  to design studies.
• Writes the statistical sections of study protocols, while consulting with internal and external experts.
• Contributes to or prepares statistical analysis plans.
• Collaborates with Data Management and Medical Research on design of eCRFs.
• Provides statistical guidance on conduct of ongoing studies.
• Collaborates with Statistical Programming on summary and analysis of study data. Writes analysis dataset and ad hoc analysis specifications.
• Contributes to observational study reports and regulatory documents e.g. DSURs, briefing documents, etc.
• Contributes to scientific articles, summarizing data collected in Alnylam studies.
• Participates in other activities and meetings to support Biostatistics and the Medical Affairs  team as needed.
• Manages CRO statistical and programming support.

Qualifications

• PhD in Biostatistics, Statistics, or equivalent with at least 5 years’ pharmaceutical biostatistics experience; or MS with at least 8 years’ relevant experience.
• Excellent written and oral communication and presentation skills.
• Experience programming in SAS.
• Interest in and basic understanding of biology and biological processes, including RNAi.

Desired Experience

• Experience in clinical development through Phase 3 (NDA Submission) and post-approval studies.
• Understanding of ICH GCP as well as general knowledge of industry practices and standards.
• Proficiency in R programming language and other statistical software, including EAST.
• Experience with CDISC, including SDTM, ADaM, CDASH.
• Experience in drug development for rare genetic diseases.

About Alnylam

Alnylam Pharmaceuticals (Nasdaq: ALNY) has led the translation of RNA interference (RNAi) into a whole new class of innovative medicines with the potential to transform the lives of people afflicted with rare and more prevalent diseases. Based on Nobel Prize-winning science, RNAi therapeutics represent a powerful, clinically validated approach to treating diseases at their genetic source by “interfering” with mRNA that cause or contribute to disease. Since our founding in 2002, Alnylam has led the RNAi Revolution and continues to turn scientific possibility into reality. 

Our people-first culture is guided by our core values: fiercely innovative, open culture, purposeful urgency, passion for excellence, and commitment to people, and these values influence how we work and the business decisions we make. Thanks to feedback from our employees over the years, we’ve been fortunate to be named a top employer around the world. Alnylam is extremely proud to have been recognized as the #1 Large Employer by Boston Globe Top Places to Work in 2022, one of Science Magazine’s Top Biopharma Employers, one of America's Most Responsible Companies for 2023 by Newsweek, a Fast Company Best Workplace for Innovators, and a Great Place to Work in Canada, France, Italy, Spain, Switzerland, and UK – among others.

At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. We are dedicated to building an environment where employees can feel that they belong, can bring their authentic selves to work, and achieve to their full potential. By empowering employees to embrace their unique differences at work, our business grows stronger with advanced and original thinking, allowing us to bring groundbreaking medicines to patients.

Qualified applicants will receive consideration for employment without regard to their race, color, religion, age, sex, sexual orientation, gender identity or expression, national origin, ethnicity, marital status, protected veteran status, disability, or any other characteristics prohibited by law. Alnylam is an E-Verify employer.

Key Responsibilities

• Partner closely with investigators and internal stakeholders to drive patient accrual.]  Partner closely with investigators and internal stakeholders as   needed regarding Alnylam clinical trials.
• Identify key opinion leaders and cultivate a network of experts for key Alnylam disease areas. 
• Develop, maintain, and execute US KOL and US Institution plans within respective geography.
• Conduct and implement a comprehensive disease awareness tactical plan within the respective geography. 
• Collaborate with health care professionals to identify opportunities for the development of algorithms and guidelines to facilitate early diagnosis
• Provide in-depth drug mechanism of action and emerging clinical information to health care providers in the respective geography. 
• Serve as a liaison to health care professionals and professional organizations and disease state advocacy groups.  Support the efforts of patient support groups and educational foundations. 
• Provide medical and scientific input into the planning and execution of advisory boards and work with experts to review speaker presentations and   provide additional medical background where requested.
• Contribute to Alnylam's achievement of Company objectives for pre-approved products.
• Provide educational meeting support at scientific congresses.
• Coordinate required medical, legal, and regulatory review and approval of all field documents for distribution or presentation.
• Requires 60-70% travel.

Qualifications

• PhD, PharmD, DNP or MD with 3 to 5 years’ industry experience.
• Proven basic science and/or clinical background to enable engagement of Health Care Professionals in a scientifically meaningful exchange.
• Prior experience in rare disease, cardiology or neurology strongly preferred.
• Experience in clinical research, patient recruitment, and investigator-sponsored trials.
• Experience in medical education and KOL management.
• Effective communication of evidence based scientific information.
• Ability to work collaboratively and cross-functionally.
• Capable of managing shifting priorities in a rapidly changing and environment
• Decision-making and accountability.
• Clear alignment with Alnylam Core Values
  • Commitment to People
  • Fiercely Innovative
  • Purposeful Sense of Urgency
  • Open Culture
  • Passion for Excellence

About Alnylam

Alnylam Pharmaceuticals (Nasdaq: ALNY) has led the translation of RNA interference (RNAi) into a whole new class of innovative medicines with the potential to transform the lives of people afflicted with rare and more prevalent diseases. Based on Nobel Prize-winning science, RNAi therapeutics represent a powerful, clinically validated approach to treating diseases at their genetic source by “interfering” with mRNA that cause or contribute to disease. Since our founding in 2002, Alnylam has led the RNAi Revolution and continues to turn scientific possibility into reality. 

 Our people-first culture is guided by our core values: fiercely innovative, open culture, purposeful urgency, passion for excellence, and commitment to people, and these values influence how we work and the business decisions we make. Thanks to feedback from our employees over the years, we’ve been fortunate to be named a top employer around the world. Alnylam is extremely proud to have been recognized as the #1 Large Employer by Boston Globe Top Places to Work in 2022, one of Science Magazine’s Top Biopharma Employers, one of America's Most Responsible Companies for 2023 by Newsweek, a Fast Company Best Workplace for Innovators, and a Great Place to Work in Canada, France, Italy, Spain, Switzerland, and UK – among others.

 At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. We are dedicated to building an environment where employees can feel that they belong, can bring their authentic selves to work, and achieve to their full potential. By empowering employees to embrace their unique differences at work, our business grows stronger with advanced and original thinking, allowing us to bring groundbreaking medicines to patients.

Qualified applicants will receive consideration for employment without regard to their race, color, religion, age, sex, sexual orientation, gender identity or expression, national origin, ethnicity, marital status, protected veteran status, disability, or any other characteristics prohibited by law. Alnylam is an E-Verify employer.

Alnylam is looking for a highly motivated, inquisitive, flexible, data driven, technology focused and a creative problem solver to join our Global Talent Acquisition Team.  This role will be focused on driving best practices, processes, and metrics to support our growing Talent Acquisition function.  The ideal candidate will have strong project management and analytical skills, thrive in an environment of change, and have a passion for process improvement and metrics.

This is a role for someone who wants to have an opportunity for tremendous impact and can bring understanding for Talent Acquisition, HR and Systems, as well as candidates and employees while constantly thinking about how to gain efficiencies and tell stories through data.

Key Responsibilities

Data Analytics & Reporting

• Create and maintain recruitment reporting, ensuring accuracy and timeliness of reporting
• Provide ad hoc reporting and analytics support as needed by TA and HR stakeholders
• Work with HR Systems team to improve reporting processes and ensure accuracy and timeliness of data as systems and processes evolve and to ensure continuity between system data sets (Applicant Tracking System, Core Human Capital Management System, etc.)
• Understand and articulate stakeholders needs to develop better reporting capabilities for current and future needs
• Deliver real-time analytics and accurate data, and generate insights, about the effectiveness of TA programs
• Ability to tell a story from the data

Talent Acquisition Process Enablement

• Actively participate and collaborate with HR/TA/L&D/Operations/ Systems to improve processes
• Document TA processes with a mindset of continuous improvement and maintain all online TA documentation to ensure process guides and SOPs are up to date for team usage
• Continue to build on automation, reporting and new functionality to support hiring efforts
• Proactively manage and get ahead of issues impacting TA processes and systems workflows
• Be the first point of contact for background check verifications and drug screen adjudications or troubleshooting, and commmunicate with TA Partners and TA Operations Lead to manage cases as they impact hiring (including delays and flagged or incomplete reports)

Extended Workforce Program 

• Support internal program management for extended workforce (contingent/temp) program
• Act as first point of contact for all classifications of contingent workers
• Drive analysis of contingent workforce and help to identify areas for optimization
• Additional projects as needed

Qualifications

• Bachelor's degree in Business, Human Resources or related field
• 4+ years of HR experience preferably in Talent Acquisition
• Technical ATS and HRIS knowledge and experience; reporting generation and data visualization experience required
• Highly skilled in excel, including strong level of comfort and familiarity with building tables and formulas, etc. (vlookups, pivot tables, etc.)
• General knowledge and understanding of compliance regulations and employment laws
• Proven record of solving complex and sometimes ambiguous problems independently
• Experience with analyzing and interpreting data to help influence decisions and/or inform stakeholders
• Strong technical aptitude with ability to learn systems quickly
• Continuous improvement mindset, courage to propose creative solutions
• Exceptional verbal and written communication skills and ability to communicate effectively across all levels
• Understand the power of influencing - experience building business cases and championing initiatives through various levels in the organization

About Alnylam

Alnylam Pharmaceuticals (Nasdaq: ALNY) has led the translation of RNA interference (RNAi) into a whole new class of innovative medicines with the potential to transform the lives of people afflicted with rare and more prevalent diseases. Based on Nobel Prize-winning science, RNAi therapeutics represent a powerful, clinically validated approach to treating diseases at their genetic source by “interfering” with mRNA that cause or contribute to disease. Since our founding in 2002, Alnylam has led the RNAi Revolution and continues to turn scientific possibility into reality.

Our people-first culture is guided by our core values: fiercely innovative, open culture, purposeful urgency, passion for excellence, and commitment to people, and these values influence how we work and the business decisions we make. Thanks to feedback from our employees over the years, we’ve been fortunate to be named a top employer around the world. Alnylam is extremely proud to have been recognized as the #1 Large Employer by Boston Globe Top Places to Work in 2022, one of Science Magazine’s Top Biopharma Employers, one of America's Most Responsible Companies for 2023 by Newsweek, a Fast Company Best Workplace for Innovators, and a Great Place to Work in Canada, France, Italy, Spain, Switzerland, and UK – among others.

At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. We are dedicated to building an environment where employees can feel that they belong, can bring their authentic selves to work, and achieve to their full potential. By empowering employees to embrace their unique differences at work, our business grows stronger with advanced and original thinking, allowing us to bring groundbreaking medicines to patients.

Qualified applicants will receive consideration for employment without regard to their race, color, religion, age, sex, sexual orientation, gender identity or expression, national origin, ethnicity, marital status, protected veteran status, disability, or any other characteristics prohibited by law. Alnylam is an E-Verify employer.

The position reports to contract testing manager and works cross-functionally with Analytical Development, Stability, Quality Assurance, Regulatory Affairs, and CMC program managers. This position is responsible for the following activities:

• Supporting and facilitating Data Review and Generation of Certificates of Analysis with minimal oversight.  
• Management of external data, protocols, reports and material demand for stability studies.
• Supporting analytical technology transfer, feasibility, method validation, and routine release and stability testing at Contract Manufacturing Organization (CMO) and Contract Testing Lab (CTL) vendors. 
• Investigating and addressing quality events for external labs in collaboration with broader team.
• Authoring technical documentation (e.g., SOPs) for CMO and CTL vendors.
• Acting as data verifier for characterization, analytical, and stability sections of regulatory submissions.
• Acting as a liaison to facilitate transfer technical expertise, trouble shoot and perform assay development to support internal and external analytical development and quality control.
• Acting as a liaison between various cross-functional departments in a CMC team, when required.
• Responsible for standards/sample shipment and associated paperwork for external labs to support GxP activities.
• Assisting and reviewing data and reports from external labs to ensure on time and compliant completion of external method qualification to support lot release. 
• Supporting timely delivery of outsourced GLP/GMP release and stability results.
• Supporting Analytical Development department / Alnylam goals and objectives.
• Some travel may be required, up to 10%.

Qualifications

• Bachelors required in applicable scientific field; chemistry preferred. Masters preferred.
• 2+ years of experience in Quality Control / GMP laboratories is required.
• Established background in analytical development, and technical QC GMP experience.
• Experience with vendor management of CMOs and/or CTLs programs is preferred.
• Ability to work independently and in compliance with cGMPs.
• Working knowledge of ICH guidelines, USP/EP/JP is preferred.
• Excellent team skills, organization, and strong communication skills
• Must be able to adhere to all laboratory safety requirements
• Must be a team player and open to change.
• Must have excellent communication and public speaking skills. Should be able to make presentations on validation and release/stability activities.

About Alnylam

Alnylam Pharmaceuticals (Nasdaq: ALNY) has led the translation of RNA interference (RNAi) into a whole new class of innovative medicines with the potential to transform the lives of people afflicted with rare and more prevalent diseases. Based on Nobel Prize-winning science, RNAi therapeutics represent a powerful, clinically validated approach to treating diseases at their genetic source by “interfering” with mRNA that cause or contribute to disease. Since our founding in 2002, Alnylam has led the RNAi Revolution and continues to turn scientific possibility into reality.

Our people-first culture is guided by our core values: fiercely innovative, open culture, purposeful urgency, passion for excellence, and commitment to people, and these values influence how we work and the business decisions we make. Thanks to feedback from our employees over the years, we’ve been fortunate to be named a top employer around the world. Alnylam is extremely proud to have been recognized as the #1 Large Employer by Boston Globe Top Places to Work in 2022, one of Science Magazine’s Top Biopharma Employers, one of America's Most Responsible Companies for 2023 by Newsweek, a Fast Company Best Workplace for Innovators, and a Great Place to Work in Canada, France, Italy, Spain, Switzerland, and UK – among others.

At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. We are dedicated to building an environment where employees can feel that they belong, can bring their authentic selves to work, and achieve to their full potential. By empowering employees to embrace their unique differences at work, our business grows stronger with advanced and original thinking, allowing us to bring groundbreaking medicines to patients.

Qualified applicants will receive consideration for employment without regard to their race, color, religion, age, sex, sexual orientation, gender identity or expression, national origin, ethnicity, marital status, protected veteran status, disability, or any other characteristics prohibited by law. Alnylam is an E-Verify employer.

We’re growing our dynamic HR team charged with building a long term strategic talent plan for a biotech business that is growing rapidly in response to programs progressing rapidly through the clinic and into commercialization.  We are looking for a dynamic, business-focused HR talent who brings to the role a love of life sciences, a curiosity which enables talent solutions and a strong consulting style in service of coaching and supporting leaders as they grow their organizations.

The Associate Director Human Resources Business Partner (HRBP) for Technical Operations & Quality (TOQ) is an individual contributor role reporting to the Senior Director, HRBP TOQ.  This individual will partner with the Senior Director, HRBP on a range of critical business and organizational issues.

As a business partner, this individual must demonstrate strong business acumen as well as functional knowledge of all aspects of human resource management.  This individual should be highly skilled at working within a network operating model environment and should possess exceptional skills in influencing others without authority. He/She is a high performing, driven, highly collaborative and humble individual, who is committed to high ethical standards for the organization, cross-functional partnership, and Alnylam’s Core Values.

This position is hybrid onsite and will be primarily located in Cambridge.

Key Responsibilities

• Provide strategic HR business leadership to the TOQ organization including but not limited to our Supply Chain and CMC Development teams.
• Partner with TOQ business leaders in defining and implementing value-added HR strategies and solutions.
• Act as an internal consultant to leaders, managers and employees providing coaching and advice on a range of organizational and people-related issues.
• Build strong partnerships across the HR organization and with key partners, specifically with Total Rewards, HR Operations, Talent Acquisition, Learning & Development, People Relations, Legal, Compliance and HRBP peers to inform and implement company-wide programs and initiatives while ensuring client’s needs are understood and met.
• Partner with TOQ leadership in creating a work environment that enables all employees to thrive in-line with Alnylam’s culture and values and diversity, equity and inclusion initiatives.
• Support TOQ leaders in the roll-out of the company’s annual culture engagement survey and in the creation of follow-up action plans.
• Partner with clients and HR partners to implement and manage all HR processes including performance management, compensation planning, talent planning, succession planning, promotions, workforce planning, investment planning, organization design, and employee career development.
• Partner with the business, Talent Acquisition and Total Rewards on the hire of key positions within the TOQ organization.
• Support the talent development needs of employees across the TOQ organization.
• Ensure robust onboarding plans are in place for new leaders and managers.
• Work with TOQ leadership to support the organizational effectiveness of teams and the implementation of organizational initiatives.

Qualifications

• Bachelor’s degree required, MBA preferred.
• Biotech or pharma industry experience required; technical ops/quality experience strongly preferred.
• 7+ year’s HR or business experience in positions of increasing responsibility.
• Successful track record of partnering with client groups.
• Dynamic and creative HR leader who can coach leaders and managers, advise on organizational design, and create robust talent planning strategies.
• Ability to design and execute project plans, identifying interdependencies and incorporating related communication/change management plans.
• Experience in influencing without authority and stakeholder management.
• Strong points of view on how to scale culture including best practices in team dynamics, working in a network operating model design, and ensuring organizational values are realized.
• Strong partner to all HR specialty areas to drive creative HR programs and solutions.
• Excellent execution skills and the ability to translate HR strategy into actionable initiatives.
• Strong consultation skills and the ability to influence at all levels is essential.
• Experience in dynamic, high growth environments.
• Ability to work as part of collaborative HR team. 

About Alnylam

Alnylam Pharmaceuticals (Nasdaq: ALNY) has led the translation of RNA interference (RNAi) into a whole new class of innovative medicines with the potential to transform the lives of people afflicted with rare and more prevalent diseases. Based on Nobel Prize-winning science, RNAi therapeutics represent a powerful, clinically validated approach to treating diseases at their genetic source by “interfering” with mRNA that cause or contribute to disease. Since our founding in 2002, Alnylam has led the RNAi Revolution and continues to turn scientific possibility into reality. 

Our people-first culture is guided by our core values: fiercely innovative, open culture, purposeful urgency, passion for excellence, and commitment to people, and these values influence how we work and the business decisions we make. Thanks to feedback from our employees over the years, we’ve been fortunate to be named a top employer around the world. Alnylam is extremely proud to have been recognized as the #1 Large Employer by Boston Globe Top Places to Work in 2022, one of Science Magazine’s Top Biopharma Employers, one of America's Most Responsible Companies for 2023 by Newsweek, a Fast Company Best Workplace for Innovators, and a Great Place to Work in Canada, France, Italy, Spain, Switzerland, and UK – among others.

At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. We are dedicated to building an environment where employees can feel that they belong, can bring their authentic selves to work, and achieve to their full potential. By empowering employees to embrace their unique differences at work, our business grows stronger with advanced and original thinking, allowing us to bring groundbreaking medicines to patients.

Qualified applicants will receive consideration for employment without regard to their race, color, religion, age, sex, sexual orientation, gender identity or expression, national origin, ethnicity, marital status, protected veteran status, disability, or any other characteristics prohibited by law. Alnylam is an E-Verify emplo
yer.

Leading all medical affairs functions of the country, including medical support of licensed products, Phase IV clinical development, new product approvals and support in the evaluation of product complaints that have clinical significance. This person will be a member on country strategic teams including the country management team and various interaction on Regional (International, Mid Sized Markets) and Global level and is the medical counterpart of the Country Manager/GM, who is located in Amsterdam.

This person will share medical/clinical expertise and strategically supports his/her counterparts in other functional areas such as Commercial, Market Access, Patient advocacy, Clinical Development, Finance, Compliance and Legal.

The Country Medical Director reports to the Sr Medical Director, Mid size Markets and is a member of the Midsize Markets Medical Leadership team.

Key Responsibilities

• Contributes to the review and implementation of the long and short-term business strategies to optimize markets for future and current products and development of rational strategic and operational plans. This includes the management of country medical budgets.
• Provides input into clinical research strategy and enables Phase IV clinical research like registries for launch and licensed products and gives input on new product development for a successful launch into the marketplace.
• Gives leadership to the Country medical team about liaison with medical organizations and opinion leaders; e.g. clinical investigators or scientific consultants.
• Ensures the presence of appropriate scientific team members at national and international meetings and other academic activities.
• Gives guidance on timelines for studies in accordance with overall Program priorities, strategic goals and ensures adherence.
• Provides direction, management and coaching of local medical team members and ensures appropriate development activities are planned and implemented.
• Contributes to the training, leadership and continuing education for commercial and medical affairs departmental staff.
• Ensures values and strategic imperatives of the company and of Medical Affairs are well understood and applied through the Medical community.
• Be member of the country management team and actively interact with other departments to ensure a good understanding of Medical Affairs roles and an excellent collaboration among teams with a common work team spirit.
• Be a member of the Midsize Markets Medical Leadership team.

Qualifications

• M.D. (Medical Doctor) and/or PhD and/or Equally qualified academic healthcare professional with proven leadership experience in Pharmaceutical or Biotechnology industry. Degree in medical/natural science (M.D., PhD) is preferred.
• A solid track record of industry working experience after completion of academic education which includes leadership roles with proven people management experience.
• Experience and network in cardiac disease preferred.
• Excellent written and verbal communication skills in English, as evidenced by a record of publications and/or public speaking. Bilingual (French) an asset.
• This position requires a mature personality with excellent leadership and interpersonal skills.
• Proven ability to interact with multiple stakeholders, both internal and external, on a variety of levels and issues and build relationships of credibility and trust.
• Broad understanding of the regulatory environment in BeNeLux.
• Extensive cross-functional project leadership experience married to an ability to operate effectively in a complex matrix organization.
• Track record in the effective management of third-party suppliers and external consultants.

The incumbent will need the following qualities/attributes:

• Strategic thinker with excellent problem solving and decision-making skills.
• Commercial acumen, demonstrating a desire and drive to work in a commercially driven business environment.
• Resilient self-starter, who can act independently and learn quickly.
• Team builder, capable of interacting effectively with external contacts and at every level within the company.
• Perceptive, creative person with the ability to contribute new ideas and to build consensus.
• Outstanding leadership skills, effective in marshaling support across an organization.
• Passion and enthusiasm for clinical development, demonstrating a commitment to maintaining standards at the highest possible level.
• Able to represent Alnylam to key external stakeholders and potential future partners.
• Able to manage complex decisions with excellent prioritization skills.
• Empathetic style with the ability to enthuse and motivate others to action.

About Alnylam

Alnylam Pharmaceuticals (Nasdaq: ALNY) has led the translation of RNA interference (RNAi) into a whole new class of innovative medicines with the potential to transform the lives of people afflicted with rare and more prevalent diseases. Based on Nobel Prize-winning science, RNAi therapeutics represent a powerful, clinically validated approach to treating diseases at their genetic source by “interfering” with mRNA that cause or contribute to disease. Since our founding in 2002, Alnylam has led the RNAi Revolution and continues to turn scientific possibility into reality.

Our people-first culture is guided by our core values: fiercely innovative, open culture, purposeful urgency, passion for excellence, and commitment to people, and these values influence how we work and the business decisions we make. Thanks to feedback from our employees over the years, we’ve been fortunate to be named a top employer around the world. Alnylam is extremely proud to have been recognized as the #1 Large Employer by Boston Globe Top Places to Work in 2022, one of Science Magazine’s Top Biopharma Employers, one of America's Most Responsible Companies for 2023 by Newsweek, a Fast Company Best Workplace for Innovators, and a Great Place to Work in Canada, France, Italy, Spain, Switzerland, and UK – among others.

At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. We are dedicated to building an environment where employees can feel that they belong, can bring their authentic selves to work, and achieve to their full potential. By empowering employees to embrace their unique differences at work, our business grows stronger with advanced and original thinking, allowing us to bring groundbreaking medicines to patients.

Leading all medical affairs functions of the country, including medical support of licensed products, Phase IV clinical development, new product approvals and support in the evaluation of product complaints that have clinical significance.  This person will be a member on country strategic teams including the country management team and various interaction on Regional (International, Mid Sized Markets) and Global level and is the medical counterpart of the Country Manager/GM, who is located in Amsterdam.

This person will share medical/clinical expertise and strategically supports his/her counterparts in other functional areas such as Commercial, Market Access, Patient advocacy, Clinical Development, Finance, Compliance and Legal.

The Country Medical Director reports to the Sr Medical Director, Mid size Markets and is a member of the Midsize Markets Medical Leadership team.

Key Responsibilities

• Contributes to the review and implementation of the long and short-term business strategies to optimize markets for future and current products and development of rational strategic and operational plans. This includes the management of country medical budgets.
• Provides input into clinical research strategy and enables Phase IV clinical research like registries for launch and licensed products and gives input on new product development for a successful launch into the marketplace.
• Gives leadership to the Country medical team about liaison with medical organizations and opinion leaders; e.g. clinical investigators or scientific consultants.
• Ensures the presence of appropriate scientific team members at national and international meetings and other academic activities.
• Gives guidance on timelines for studies in accordance with overall Program priorities, strategic goals and ensures adherence.
• Provides direction, management and coaching of local medical team members and ensures appropriate development activities are planned and implemented.
• Contributes to the training, leadership and continuing education for commercial and medical affairs departmental staff.
• Ensures values and strategic imperatives of the company and of Medical Affairs are well understood and applied through the Medical community.
• Be member of the country management team and actively interact with other departments to ensure a good understanding of Medical Affairs roles and an excellent collaboration among teams with a common work team spirit.
• Be a member of the Midsize Markets Medical Leadership team.

Qualifications

• M.D. (Medical Doctor) and/or PhD and/or Equally qualified academic healthcare professional with proven leadership experience in Pharmaceutical or Biotechnology industry. Degree in medical/natural science (M.D., PhD) is preferred.
• A solid track record of industry working experience after completion of academic education which includes leadership roles with proven people management experience.
• Experience and network in cardiac disease preferred.
• Excellent written and verbal communication skills in English, as evidenced by a record of publications and/or public speaking. Bilingual (French) an asset.
• This position requires a mature personality with excellent leadership and interpersonal skills.
• Proven ability to interact with multiple stakeholders, both internal and external, on a variety of levels and issues and build relationships of credibility and trust.
• Broad understanding of the regulatory environment in BeNeLux.
• Extensive cross-functional project leadership experience married to an ability to operate effectively in a complex matrix organization.
• Track record in the effective management of third-party suppliers and external consultants.

The incumbent will need the following qualities/attributes:

• Strategic thinker with excellent problem solving and decision-making skills.
• Commercial acumen, demonstrating a desire and drive to work in a commercially driven business environment.
• Resilient self-starter, who can act independently and learn quickly.
• Team builder, capable of interacting effectively with external contacts and at every level within the company.
• Perceptive, creative person with the ability to contribute new ideas and to build consensus.
• Outstanding leadership skills, effective in marshaling support across an organization.
• Passion and enthusiasm for clinical development, demonstrating a commitment to maintaining standards at the highest possible level.
• Able to represent Alnylam to key external stakeholders and potential future partners.
• Able to manage complex decisions with excellent prioritization skills.
• Empathetic style with the ability to enthuse and motivate others to action.

About Alnylam

Alnylam Pharmaceuticals (Nasdaq: ALNY) has led the translation of RNA interference (RNAi) into a whole new class of innovative medicines with the potential to transform the lives of people afflicted with rare and more prevalent diseases. Based on Nobel Prize-winning science, RNAi therapeutics represent a powerful, clinically validated approach to treating diseases at their genetic source by “interfering” with mRNA that cause or contribute to disease. Since our founding in 2002, Alnylam has led the RNAi Revolution and continues to turn scientific possibility into reality. 

Our people-first culture is guided by our core values: fiercely innovative, open culture, purposeful urgency, passion for excellence, and commitment to people, and these values influence how we work and the business decisions we make. Thanks to feedback from our employees over the years, we’ve been fortunate to be named a top employer around the world. Alnylam is extremely proud to have been recognized as the #1 Large Employer by Boston Globe Top Places to Work in 2022, one of Science Magazine’s Top Biopharma Employers, one of America's Most Responsible Companies for 2023 by Newsweek, a Fast Company Best Workplace for Innovators, and a Great Place to Work in Canada, France, Italy, Spain, Switzerland, and UK – among others. 

At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. We are dedicated to building an environment where employees can feel that they belong, can bring their authentic selves to work, and achieve to their full potential. By empowering employees to embrace their unique differences at work, our business grows stronger with advanced and original thinking, allowing us to bring groundbreaking medicines to patients.

With limited supervision, this individual will manufacture clinical products in Train 1 at the Norton Manufacturing Facility ensuring safe, efficient and cGMP-compliant operations at all times.  Responsibilities include but are not limited to operation of production equipment in the area of weigh/dispense, solution preparation, chemical synthesis, cleavage and deprotection, UF/DF, HPLC, annealing, concentration and lyophilization.  Requires interaction with support groups (Facilities, Process Development, QC, QA and Validation etc.) to ensure accurate and well managed daily plant activities. This individual will be responsible for coordinating either chemical synthesis or HPLC suite operations.

Key Responsibilities

• This individual will carry out cGMP manufacturing operations utilizing Standard Operating Procedures (SOP) and Batch Records. Responsibilities include:
• Troubleshoot and resolve process and equipment related issues and interact with support groups to ensure production targets are met and product and process comply with cGMPs, EHS and corporate policies.
• Ensure all operations and documentation conform to cGMP standards and that all SOPs and batch records are maintained to reflect current manufacturing practices.
• Gain knowledge of and maintain status as a Qualified Trainer for synthesis or HPLC operation areas. Provide technical training to junior employees; meet and maintain training material requirements
• Be the SME for the synthesis or HPLC operation areas. This includes SOP, Unicorn methods, MBR, training material, and form ownership for the primary operation (synthesis or HPLC) and all supporting operations (buffer/column packing or solvent prep/column packing)
• Use technical writing skills to initiate and provide subject matter expertise for deviations, CAPAs and change controls as required.
• Identify and support implementation of continuous improvement projects.
• Create work orders as needed, and coordinate activities to prevent maintenance and calibration events from impacting schedule.
• Perform Batch Record, Logbook requests and review manufacturing documentation to ensure compliance.
• Propose and review documentation revisions.
• Carry out work in a safe manner, notifying management of safety issues and risks.
• Support execution of equipment qualification and review associated protocols.
• On-call support during off hours may be required.

Qualifications

• Must possess a mechanical and scientific aptitude and be able to clearly and thoroughly document all work on existing forms and records.
• Bachelors of Science (BS) degree preferred and a minimum of 4 - 6 years’ experience in a regulated GMP facility. Minimum requirements may be substituted for the equivalent combination of education and experience in the industry.
• Safety and the ability to maintain a compliant, highly effective and efficient production environment is critical.
• High level of attention to details in both operations and documentation is required.
• Familiarity with Unicorn software is a plus.

About Alnylam

Alnylam Pharmaceuticals (Nasdaq: ALNY) has led the translation of RNA interference (RNAi) into a whole new class of innovative medicines with the potential to transform the lives of people afflicted with rare and more prevalent diseases. Based on Nobel Prize-winning science, RNAi therapeutics represent a powerful, clinically validated approach to treating diseases at their genetic source by “interfering” with mRNA that cause or contribute to disease. Since our founding in 2002, Alnylam has led the RNAi Revolution and continues to turn scientific possibility into reality. 

Our people-first culture is guided by our core values: fiercely innovative, open culture, purposeful urgency, passion for excellence, and commitment to people, and these values influence how we work and the business decisions we make. Thanks to feedback from our employees over the years, we’ve been fortunate to be named a top employer around the world. Alnylam is extremely proud to have been recognized as the #1 Large Employer by Boston Globe Top Places to Work in 2022, one of Science Magazine’s Top Biopharma Employers, one of America's Most Responsible Companies for 2023 by Newsweek, a Fast Company Best Workplace for Innovators, and a Great Place to Work in Canada, France, Italy, Spain, Switzerland, and UK – among others.

At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. We are dedicated to building an environment where employees can feel that they belong, can bring their authentic selves to work, and achieve to their full potential. By empowering employees to embrace their unique differences at work, our business grows stronger with advanced and original thinking, allowing us to bring groundbreaking medicines to patients.

Qualified applicants will receive consideration for employment without regard to their race, color, religion, age, sex, sexual orientation, gender identity or expression, national origin, ethnicity, marital status, protected veteran status, disability, or any other characteristics prohibited by law. Alnylam is an E-Verify employer.

As the Head of Financial Operations reporting to the Chief Accounting Officer this role will lead the company’s buildout of key global finance processes including procure to pay and order to cash.

This role will work with stakeholders across company, including procurement, accounting / controllership, legal, compliance, commercial and supply chain to develop efficient processes to support Alnylam’s growing operational footprint. 

The ideal candidate for this role will have experience in a fast- paced high growth environment.  Excellent communication, leadership, and technical skills will be essential for this role as well as a passion to be a part of the company’s growth

Key Responsibilities

• Develop and refine global financial processes including procure to pay and order to cash to ensure these processes are efficiently designed to support the global scaling of the business.
• Review and administer the use and management of the Accounts Payable system (and any related systems interfaces) to ensure optimal workflow along the entire Procure to Pay continuum.
• Manage Supplier listing and ensure documentation and information are complete and accurate, along with ensuring timely responses to supplier and internal business partner inquiries and quickly resolving issues.
• Stay abreast of industry best practices across Procure to Pay, collaborating with supply chain, finance, business systems, and operations teams.
• Lead project activities related to accounts payable functions bringing exceptional value to the company through total cost reduction, streamlining workflow, automation etc.
• Develop and execute plans to train the organization on purchase requisition process to ensure adherence to company policies and on-time and accurate payments to vendors.
• Monitor and enhance KPI and related monitoring, reporting and analyses to drive effective process improvements to lead and maintain compliance in all Accounts Payable related activities.
• Work with Supply Chain, Commercial and Finance to develop & implement in-house OTC capabilities.
• Oversee the company’s T&E policy and related processes and systems
• Deliver on long term vision for global finance shared services strategy to support long term growth of the business.
• Collaborate with finance and business functions to lead and coordinate key initiatives to enhance the company’s financial systems
• Partner with other finance functions to lead key process improvements
• Drive the overall sustainment and prioritization process for financial systems
• Oversee master data requirements and strategy
• Understanding of the Company’s internal controls compliance, working to strengthen internal controls and ensure the control environment is operating effectively in a dynamic and scaling setting
• Mentor and develop existing finance operations staff in order to achieve department and company goals.
• Manage team resourcing, performance levels, & development plan for business continuity.

Qualifications

• Must have 12+ years experience in managing accounts payable and order to cash functions with previous track record of managing teams across multiple geographies
• Bachelor’s Degree in Finance / Accounting required, MBA preferred
• CPA certification preferred
• Global commercial biotech experience preferred
• Advanced ERP systems (SAP strongly preferred), Excel and PowerPoint skills
• Hands on experience with SOX processes and procedures

About Alnylam

Alnylam Pharmaceuticals (Nasdaq: ALNY) has led the translation of RNA interference (RNAi) into a whole new class of innovative medicines with the potential to transform the lives of people afflicted with rare and more prevalent diseases. Based on Nobel Prize-winning science, RNAi therapeutics represent a powerful, clinically validated approach to treating diseases at their genetic source by “interfering” with mRNA that cause or contribute to disease. Since our founding in 2002, Alnylam has led the RNAi Revolution and continues to turn scientific possibility into reality. 

Our people-first culture is guided by our core values: fiercely innovative, open culture, purposeful urgency, passion for excellence, and commitment to people, and these values influence how we work and the business decisions we make. Thanks to feedback from our employees over the years, we’ve been fortunate to be named a top employer around the world. Alnylam is extremely proud to have been recognized as the #1 Large Employer by Boston Globe Top Places to Work in 2022, one of Science Magazine’s Top Biopharma Employers, one of America's Most Responsible Companies for 2023 by Newsweek, a Fast Company Best Workplace for Innovators, and a Great Place to Work in Canada, France, Italy, Spain, Switzerland, and UK – among others.

At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. We are dedicated to building an environment where employees can feel that they belong, can bring their authentic selves to work, and achieve to their full potential. By empowering employees to embrace their unique differences at work, our business grows stronger with advanced and original thinking, allowing us to bring groundbreaking medicines to patients.

Qualified applicants will receive consideration for employment without regard to their race, color, religion, age, sex, sexual orientation, gender identity or expression, national origin, ethnicity, marital status, protected veteran status, disability, or any other characteristics prohibited by law. Alnylam is an E-Verify employer.