Public Company

Fulcrum Therapeutics

Modulating gene expression to treat the root cause of genetically defined diseases


We launched Fulcrum Therapeutics with a bold vision: To change the course of genetically defined diseases by treating them at their root cause. Our approach to drug discovery generates significant insights into disease biology and allows us to think creatively about the best way to modulate and balance gene expression. The result: FulcrumSeek, a patient-focused product engine designed to systematically identify high-value, de-risked targets at speed and scale for rare genetic diseases. We take great pride in being purposeful patient partners who do this work, not just for patients, but with patients. We have a culture of trust and transparency which enables our employees to focus on our mission and the science behind it. In addition, we are invested in our people and want to ensure they have the tools and training they need to succeed. This allows our playful spirit to come alive, making work more enjoyable for our entire Fulcrew.


Founded 2016
Type Public
Longevity related Yes
Location Cambridge, Massachusetts, USA

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